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The coronavirus disease (COVID-19) pandemic has changed our lives and still poses a challenge to science. Numerous studies have contributed to a better understanding of the pandemic. In particular, inhalation of aerosolised pathogens has…

种群与进化 · 定量生物学 2022-09-02 Simon Rahn , Marion Gödel , Gerta Köster , Gesine Hofinger

In this paper, we develop a method to estimate the infection-rate of a disease, over a region, as a field that varies in space and time. To do so, we use time-series of case-counts of symptomatic patients as observed in the areal units that…

应用统计 · 统计学 2024-06-19 Cosmin Safta , Wyatt Bridgman , Jaideep Ray

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

统计方法学 · 统计学 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu

This paper studies an epidemic model with nonlocal dispersals. We focus on the influences of initial data and nonlocal dispersals on its spatial propagation. Here the initial data stand for the spatial concentrations of infectious agent and…

偏微分方程分析 · 数学 2020-07-31 Wen-Bing Xu , Wan-Tong Li , Shigui Ruan

As an emergent infectious disease outbreak unfolds, public health response is reliant on information on key epidemiological quantities, such as transmission potential and serial interval. Increasingly, transmission models fit to incidence…

种群与进化 · 定量生物学 2015-06-29 Aaron A. King , Matthieu Domenech de Cellès , Felicia M. G. Magpantay , Pejman Rohani

During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19,…

Background: Recently developed techniques to study the spread of infectious diseases through networks make assumptions that the initial proportion infected is infinitesimal and the population behavior is static throughout the epidemic. The…

种群与进化 · 定量生物学 2012-08-17 Joel C. Miller

When analysing new emerging infectious disease outbreaks one typically has observational data over a limited period of time and several parameters to estimate, such as growth rate, R0, serial or generation interval distribution, latent and…

应用统计 · 统计学 2018-03-06 Tom Britton , Gianpaolo Scalia Tomba

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

定量方法 · 定量生物学 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

Mathematical models of SARS-CoV-2 spread are used for guiding the design of mitigation steps aimed at containing and decelerating the contagion, and at identifying impending breaches of health care system surge capacity. The challenges of…

种群与进化 · 定量生物学 2020-06-17 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

Mathematical models in epidemiology are an indispensable tool to determine the dynamics and important characteristics of infectious diseases. Apart from their scientific merit, these models are often used to inform political decisions and…

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

统计方法学 · 统计学 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian

The surprisingly mercurial Covid-19 pandemic has highlighted the need to not only accelerate research on infectious disease, but to also study them using novel techniques and perspectives. A major contributor to the difficulty of containing…

种群与进化 · 定量生物学 2022-07-21 Aminur Rahman , Angela Peace , Ramesh Kesawan , Souparno Ghosh

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

应用统计 · 统计学 2018-01-30 Tom Britton

Early outbreak detection is a key aspect in the containment of infectious diseases, as it enables the identification and isolation of infected individuals before the disease can spread to a larger population. Instead of detecting unexpected…

机器学习 · 计算机科学 2021-10-19 Michael Rapp , Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

The ability to directly record human face-to-face interactions increasingly enables the development of detailed data-driven models for the spread of directly transmitted infectious diseases at the scale of individuals. Complete coverage of…

We propose an extension of the classical susceptible infectious recovered (SIR) model that incorporates the effects of spatial propagation of an epidemic through a small number of additional compartments. The model is designed to capture…

数值分析 · 数学 2026-03-02 M. Soledad Aronna , Mariana Bergonzi , Ernesto Kofman

Infectious diseases usually originate from a specific location within a city. Due to the heterogenous distribution of population and public facilities, and the structural heterogeneity of human mobility network embedded in space, infectious…

物理与社会 · 物理学 2022-04-25 Kang Liu , Ling Yin , Jianzhang Xue

The integration of empirical data in computational frameworks to model the spread of infectious diseases poses challenges that are becoming pressing with the increasing availability of high-resolution information on human mobility and…

种群与进化 · 定量生物学 2013-04-24 Anna Machens , Francesco Gesualdo , Caterina Rizzo , Alberto E Tozzi , Alain Barrat , Ciro Cattuto

Background: The global spread of the severe acute respiratory syndrome (SARS) epidemic has clearly shown the importance of considering the long-range transportation networks in the understanding of emerging diseases outbreaks. The…

其他定量生物学 · 定量生物学 2008-01-16 Vittoria Colizza , Alain Barrat , Marc Barthelemy , Alessandro Vespignani
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