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X-ray phase contrast imaging holds great promise for improving the visibility of light-element materials such as soft tissues and tumors. Single-mask differential phase contrastnimaging method stands out as a simple and effective approach…

图像与视频处理 · 电气工程与系统科学 2024-02-02 Jingcheng Yuan , Mini Das

Phase-contrast imaging is an emerging technology that may increase the signal-difference-to-noise ratio in medical imaging. One of the most promising phase-contrast techniques is Talbot interferometry, which, combined with energy-sensitive…

The ability to gain insights into the 3D properties of artificial or biological systems is often critical. However, 3D structures are difficult to retrieve at low dose and with extremely fast processing, as most techniques are based on…

图像与视频处理 · 电气工程与系统科学 2019-09-11 J. Duarte , R. Cassin , J. Huijts , M. Kholodtsova , B. Iwan , M. Kovacev , M. Fajardo , F. Fortuna , L. Delbecq , W. Boutu , H. Merdji

Medical differential phase contrast x-ray imaging (DPCI) promises improved soft-tissue contrast at lower x-ray dose. The dose strongly depends on both the angular sensitivity and on the visibility of a grating-based Talbot-Lau…

医学物理 · 物理学 2016-03-23 Oliver Preusche

Optical fiber technologies enable high-speed communication, medical imaging, and advanced sensing. Among the techniques for the characterization of optical fibers, Xray computed tomography has recently emerged as a versatile non-destructive…

In this work, a general theoretical framework is presented to explain the formation of the phase signal in an X-ray microscope integrated with a grating interferometer, which simultaneously enables the high spatial resolution imaging and…

光学 · 物理学 2022-09-28 Jiecheng Yang , Yongshuai Ge , Dong Liang , Hairong Zheng

Low dose, high contrast x-ray imaging is of general interest in medical diagnostic applications. X-ray Mach-Zehnder interferometers using collimated synchrotron beams demonstrate the highest levels of phase contrast under a given exposure…

Electron tomography is a technique used in both materials science and structural biology to image features well below optical resolution limit. In this work, we present a new algorithm for reconstructing the three-dimensional(3D)…

信号处理 · 电气工程与系统科学 2018-07-12 David Ren , Michael Chen , Laura Waller , Colin Ophus

Existing methods in nanoscale connectomics are at present too slow to map entire mammalian brains. As an emerging approach, expansion microscopy (ExM) has enormous promise, yet it still suffers from throughput limitations. Mapping the human…

定量方法 · 定量生物学 2026-01-21 Logan Thrasher Collins

How to evaluate and compare image quality from different sub-micrometer (sub$\mu$) CT scans? A simple test phantom made of polymer microbeads is used for recording projection images as well as 13 CT scans in a number of commercial and…

Multi-energy CT has long demonstrated its ability to enhance image quality with material decomposition. Yet, it has largely been limited to applications that already have high contrast. More recently, x-ray phase-contrast (XPC) imaging has…

医学物理 · 物理学 2025-08-19 Giavanna Jadick , Patrick La Rivière

These tutorials introduce some basics of imaging with coherent X-rays, focusing on phase contrast. We consider the transport-of-intensity equation, as one particular method for X-ray phase contrast imaging among many, before passing on to…

图像与视频处理 · 电气工程与系统科学 2019-02-28 David M. Paganin , Daniele Pelliccia

Scanning transmission electron microscopy (STEM) has been extensively used for imaging complex materials down to atomic resolution. The most commonly employed STEM modality, annular dark-field imaging, produces easily-interpretable…

Following the recent developement of Fourier ptychographic microscopy (FPM) in the visible range by Zheng et al. (2013), we propose an adaptation for hard x-rays. FPM employs ptychographic reconstruction to merge a series of low-resolution,…

仪器与探测器 · 物理学 2016-09-27 H. Simons , H. F. Poulsen , J. P. Guigay , C. Detlefs

X-ray imaging allows for a non-invasive image of the internal structure of an object. The most common form of X-ray imaging, projectional radiography, is simply a projection or "shadow" of the object rather than a point-to-point image…

光学 · 物理学 2020-10-15 Thomas A. Smith , Zhehui Wang , Yanhua Shih

Accurate characterization of the inner surface of X-ray monocapillary optics (XMCO) is of great significance in X-ray optics research. Compared with other characterization methods, the micro computed tomography (micro-CT) method has its…

仪器与探测器 · 物理学 2021-10-27 Zhao Wang , Kai Pan , Shuang Zhang , Zhuxuan Duo , Zhiguo Liu , Tianxi Sun

Quantum imaging employs the nonclassical correlation of photons to break through the noise limitation of classical imaging, realizing high sensitivity, high SNR imaging and multifunctional image processing. To enhance the flexibility and…

This study describes a new approach for material decomposition in x-ray imaging, utilising phase contrast to both increase sensitivity to weakly-attenuating samples and to act as a complementary measurement to attenuation, therefore…

In X-ray imaging, photons are transmitted through and absorbed by the subject, but are also scattered in significant quantities. Previous attempts to use scattered photons for biological imaging used pencil or fan beam illumination. Here we…

Coherent X-ray diffraction microscopy is a method of imaging non-periodic isolated objects at resolutions only limited, in principle, by the largest scattering angles recorded. We demonstrate X-ray diffraction imaging with high resolution…