相关论文: Compressive Instabilities Enable Cell-Induced Extr…
Parametric instabilities are a known feature of periodically driven dynamic systems; at particular frequencies and amplitudes of the driving modulation, the system's quasi-periodic response undergoes a frequency lock-in, leading to a…
Counter-streaming systems are a canonical model for beam-plasma instabilities, such as the filamentation instability, which is critical in high energy density physics. However, scenarios involving intersecting fast electron beams break the…
Recent experiments have exploited elastic instabilities in membranes to create complex patterns. However, the rational design of such structures poses many challenges, as they are products of nonlinear elastic behavior. We pose a simple…
If carbon fibre layers are prevented from slipping over one another as they consolidate onto a non-trivial geometry, they can be particularly susceptible to wrinkling/buckling instabilities. A one dimensional model for wrinkling during…
We apply a recently developed model of cytoskeletal force generation to study a cell intrinsic contractility, as well as its response to external loading. The model is based on a non-equilibrium thermodynamic treatment of the…
Compliant environments can mediate interactions between mechanically active cells like fibroblasts. Starting with a phenomenological model for the behaviour of single cells, we use extensive Monte Carlo simulations to predict non-trivial…
The equilibrium behavior of a system of elastic layers under tension in the presence of correlated disorder is studied using functional renormalization group techniques. The model exhibits many of the features of the Bose glass phase of…
Interfaces between stratified epithelia and their supporting stromas commonly exhibit irregular shapes. Undulations are particularly pronounced in dysplastic tissues and typically evolve into long, finger-like protrusions in carcinomas. In…
Disordered filamentous networks with compliant crosslinks exhibit a low linear elastic shear modulus at small strains, but stiffen dramatically at high strains. Experiments have shown that the elastic modulus can increase by up to three…
Disordered soft materials, such as fibrous networks in biological contexts exhibit a nonlinear elastic response. We study such nonlinear behavior with a minimal model for networks on lattice geometries with simple Hookian elements with…
In equilibrium, the physical properties of matter are set by the interactions between the constituents. In contrast, the energy input of the individual components controls the behavior of synthetic or living active matter. Great progress…
We study the elasticity of random stiff fiber networks. The elastic response of the fibers is characterized by a central force stretching stiffness as well as a bending stiffness that acts transverse to the fiber contour. Previous studies…
Movement of cell clusters along extracellular matrices (ECM) during tissue development, wound healing, and early stage of cancer invasion involve various inter-connected migration modes such as: (1) cell movement within clusters, (2)…
We report detailed theoretical investigations of the micro-mechanics and bulk elastic properties of composites consisting of randomly distributed stiff fibers embedded in an elastic matrix in two and three dimensions. Recent experiments…
Spatially confined rigid membranes reorganize their morphology in response to the imposed constraints. A crumpled elastic sheet presents a complex pattern of random folds focusing the deformation energy while compressing a membrane resting…
We discuss the plastic behavior of an amorphous matrix reinforced by hard particles. A mesoscopic depinning-like model accounting for Eshelby elastic interactions is implemented. Only the effect of a plastic disorder is considered.…
Biological soft tissues exhibit elastic properties which can be dramatically different from rubber-type materials (elastomers). To gain a better understanding of the role of constitutive relationships in determining material responses under…
We have studied experimentally and theoretically the response of randomly folded hyperelastic and elastoplastic sheets on the uniaxial compression loading and the statistical properties of crumpling networks. The results of these studies…
Two-dimensional shape-morphing networks are common in biological systems and have garnered attention due to their nontrivial physical properties that emanate from their cellular nature. Here, we present the fabrication and characterization…
In layered materials, a common mode of deformation involves buckling of the layers under tensile deformation in the direction perpendicular to the layers. The instability mechanism, which operates in elastic materials from geological to…