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We propose a dynamic allocation procedure that increases power and efficiency when measuring an average treatment effect in sequential randomized trials. Subjects arrive iteratively and are either randomized or paired via a matching…

统计方法学 · 统计学 2013-05-23 Adam Kapelner , Abba Krieger

The contextual bandit framework is widely used to solve sequential optimization problems where the reward of each decision depends on auxiliary context variables. In settings such as medicine, business, and engineering, the decision maker…

机器学习 · 统计学 2025-03-17 Kevin Li , Eric Laber

In clinical practice and biomedical research, measurements are often collected sparsely and irregularly in time while the data acquisition is expensive and inconvenient. Examples include measurements of spine bone mineral density, cancer…

机器学习 · 统计学 2021-08-05 Łukasz Kidziński , Trevor Hastie

There is increasing interest in allocating treatments based on observed individual characteristics: examples include targeted marketing, individualized credit offers, and heterogeneous pricing. Treatment personalization introduces…

计量经济学 · 经济学 2023-04-06 Evan Munro

Unsupervised domain adaptation is useful in medical image segmentation. Particularly, when ground truths of the target images are not available, domain adaptation can train a target-specific model by utilizing the existing labeled images…

图像与视频处理 · 电气工程与系统科学 2021-06-17 Fuping Wu , Xiahai Zhuang

We consider the problem of estimating a dose-response curve. Continuous treatments arise often in practice, e.g. in the form of time spent on an operation, distance traveled to a location or dosage of a drug. Letting $A$ denote a continuous…

统计方法学 · 统计学 2026-04-14 Matteo Bonvini , Edward H. Kennedy

This paper studies a dynamic real-time optimization in the context of model-based time-optimal operation of batch processes under parametric model mismatch. In order to tackle the model-mismatch issue, a receding-horizon policy is usually…

系统与控制 · 电气工程与系统科学 2019-07-10 Radoslav Paulen , Miroslav Fikar

We consider data-driven reachability analysis of discrete-time stochastic dynamical systems using conformal inference. We assume that we are not provided with a symbolic representation of the stochastic system, but instead have access to a…

系统与控制 · 电气工程与系统科学 2023-09-19 Navid Hashemi , Xin Qin , Lars Lindemann , Jyotirmoy V. Deshmukh

We study the selection of covariate adjustment sets for estimating the value of point exposure dynamic policies, also known as dynamic treatment regimes, assuming a non-parametric causal graphical model with hidden variables, in which at…

统计理论 · 数学 2020-05-27 Ezequiel Smucler , Facundo Sapienza , Andrea Rotnitzky

Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…

机器学习 · 计算机科学 2021-05-18 Chang Lu , Chandan K. Reddy , Prithwish Chakraborty , Samantha Kleinberg , Yue Ning

The Dynamical Gaussian Process Latent Variable Models provide an elegant non-parametric framework for learning the low dimensional representations of the high-dimensional time-series. Real world observational studies, however, are often…

机器学习 · 计算机科学 2019-09-26 Thanh Le , Vasant Honavar

Predicated on the increasing abundance of electronic health records, we investi- gate the problem of inferring individualized treatment effects using observational data. Stemming from the potential outcomes model, we propose a novel multi-…

机器学习 · 计算机科学 2017-05-30 Ahmed M. Alaa , Mihaela van der Schaar

Many applied decision-making problems have a dynamic component: The policymaker needs not only to choose whom to treat, but also when to start which treatment. For example, a medical doctor may choose between postponing treatment (watchful…

统计方法学 · 统计学 2020-05-01 Xinkun Nie , Emma Brunskill , Stefan Wager

We consider a network of autonomous agents whose outputs are actions in a game with coupled constraints. In such network scenarios, agents seeking to minimize coupled cost functions using distributed information while satisfying the coupled…

系统与控制 · 电气工程与系统科学 2021-04-26 Andrew R. Romano , Lacra Pavel

Mechatronic systems have increasingly high performance requirements for motion control. The low-frequency contribution of the flexible dynamics, i.e. the compliance, should be compensated for by means of snap feedforward to achieve high…

系统与控制 · 电气工程与系统科学 2023-01-16 Max van Haren , Maurice Poot , Jim Portegies , Tom Oomen

Shortcomings of randomized clinical trials are pronounced in urgent health crises, when rapid identification of effective treatments is critical. Leveraging short-term surrogates in real-world data (RWD) can guide policymakers evaluating…

统计方法学 · 统计学 2021-04-13 Larry Han , Xuan Wang , Tianxi Cai

Longitudinal data are often plagued with sparsity of time points where measurements are available. The functional data analysis perspective has been shown to provide an effective and flexible approach to address this problem for the case…

统计方法学 · 统计学 2017-02-13 Matthew Dawson , Hans-Georg Müller

I develop a continuous functional framework for spatial treatment effects grounded in Navier-Stokes partial differential equations. Rather than discrete treatment parameters, the framework characterizes treatment intensity as continuous…

计量经济学 · 经济学 2025-10-28 Tatsuru Kikuchi

Modern medical research demands specialized causal inference methods evaluating complex continuous-time dynamic treatment regimens using observational data. For instance, obtaining the causal effects of intravenous administration, a…

统计方法学 · 统计学 2026-04-02 Haiyan Zhu , Yingchun Zhou

A fairly reliable trend in deep reinforcement learning is that the performance scales with the number of parameters, provided a complimentary scaling in amount of training data. As the appetite for large models increases, it is imperative…

机器学习 · 计算机科学 2023-06-14 Bogdan Mazoure , Walter Talbott , Miguel Angel Bautista , Devon Hjelm , Alexander Toshev , Josh Susskind