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Causal discovery, the learning of causality in a data mining scenario, has been of strong scientific and theoretical interest as a starting point to identify "what causes what?" Contingent on assumptions and a proper learning algorithm, it…

统计方法学 · 统计学 2022-05-23 Gabriel Ruiz , Oscar Hernan Madrid Padilla , Qing Zhou

Graph topology inference of network processes with co-evolving and interacting time-series is crucial for network studies. Vector autoregressive models (VAR) are popular approaches for topology inference of directed graphs; however, in…

机器学习 · 计算机科学 2020-11-18 M. Ali Vosoughi , Axel Wismuller

Introduced more than a half century ago, Granger causality has become a popular tool for analyzing time series data in many application domains, from economics and finance to genomics and neuroscience. Despite this popularity, the validity…

统计方法学 · 统计学 2021-05-10 Ali Shojaie , Emily B. Fox

Latent confounding has been a long-standing obstacle for causal reasoning from observational data. One popular approach is to model the data using acyclic directed mixed graphs (ADMGs), which describe ancestral relations between variables…

机器学习 · 计算机科学 2023-03-23 Matthew Ashman , Chao Ma , Agrin Hilmkil , Joel Jennings , Cheng Zhang

We consider the problem of learning a set of direct causes of a target variable from an observational joint distribution. Learning directed acyclic graphs (DAGs) that represent the causal structure is a fundamental problem in science.…

统计方法学 · 统计学 2025-06-24 Juraj Bodik , Valérie Chavez-Demoulin

Bayesian causal discovery offers the power to quantify epistemic uncertainties among a broad range of structurally diverse causal theories potentially explaining the data, represented in forms of directed acyclic graphs (DAGs). However,…

机器学习 · 计算机科学 2024-08-30 Nu Hoang , Bao Duong , Thin Nguyen

Identifying directed interactions between species from time series of their population densities has many uses in ecology. This key statistical task is equivalent to causal time series inference, which connects to the Granger causality (GC)…

种群与进化 · 定量生物学 2020-11-10 Frederic Barraquand , Coralie Picoche , Matteo Detto , Florian Hartig

The increasing availability of interventional data offers new opportunities for causal discovery, with gene perturbation studies providing a prominent example. Such data are typically count-valued and subject to substantial measurement…

统计方法学 · 统计学 2026-03-30 Yijiao Zhang , Hongzhe Li

Biological foundation models have shown strong performance in single-cell representation learning by applying transformer architectures directly to gene-expression matrices. However, these approaches predominantly operate in static settings…

机器学习 · 计算机科学 2026-05-28 Manuel Dileo , Andrea Sottoriva

We consider the problem of estimating the differences between two causal directed acyclic graph (DAG) models with a shared topological order given i.i.d. samples from each model. This is of interest for example in genomics, where changes in…

统计方法学 · 统计学 2018-11-08 Yuhao Wang , Chandler Squires , Anastasiya Belyaeva , Caroline Uhler

Causal models seek to unravel the cause-effect relationships among variables from observed data, as opposed to mere mappings among them, as traditional regression models do. This paper introduces a novel causal discovery algorithm designed…

机器学习 · 计算机科学 2024-10-03 Saeed Mohseni-Sehdeh , Walid Saad

Causal graphs, such as directed acyclic graphs (DAGs) and partial ancestral graphs (PAGs), represent causal relationships among variables in a model. Methods exist for learning DAGs and PAGs from data and for converting DAGs to PAGs.…

机器学习 · 统计学 2018-01-19 Nishant Subramani

The feed-forward relationship naturally observed in time-dependent processes and in a diverse number of real systems -such as some food-webs and electronic and neural wiring- can be described in terms of so-called directed acyclic graphs…

物理与社会 · 物理学 2015-05-19 Joaquín Goñi , Bernat Corominas-Murtra , Ricard V. Solé , Carlos Rodríguez-Caso

Directed acyclic graphs (DAGs) are frequently used in epidemiology as a method to encode causal inference assumptions. We propose the DAGWOOD framework to bring many of those encoded assumptions to the forefront. DAGWOOD combines a root DAG…

统计方法学 · 统计学 2021-11-25 Noah A Haber , Mollie E Wood , Sarah Wieten , Alexander Breskin

Dynamic gene-regulatory networks are complex since the number of potential components involved in the system is very large. Estimating dynamic networks is an important task because they compromise valuable information about interactions…

统计方法学 · 统计学 2012-05-15 Antonino Abbruzzo , Ernst Wit

In this article, we propose a new hypothesis testing method for directed acyclic graph (DAG). While there is a rich class of DAG estimation methods, there is a relative paucity of DAG inference solutions. Moreover, the existing methods…

机器学习 · 统计学 2023-05-25 Chengchun Shi , Yunzhe Zhou , Lexin Li

An acyclic causal structure can be described with directed acyclic graph (DAG), where arrows indicate the possibility of direct causation. The task of learning this structure from data is known as "causal discovery." Diverse populations or…

机器学习 · 计算机科学 2024-10-17 Bijan Mazaheri , Spencer Gordon , Yuval Rabani , Leonard Schulman

This paper explores the potential of the transformer models for learning Granger causality in networks with complex nonlinear dynamics at every node, as in neurobiological and biophysical networks. Our study primarily focuses on a…

机器学习 · 计算机科学 2025-10-21 Ziyu Lu , Anika Tabassum , Shruti Kulkarni , Lu Mi , J. Nathan Kutz , Eric Shea-Brown , Seung-Hwan Lim

Gene regulatory network inference (GRNI) aims to discover how genes causally regulate each other from gene expression data. It is well-known that statistical dependencies in observed data do not necessarily imply causation, as spurious…

机器学习 · 计算机科学 2025-11-05 Gongxu Luo , Haoyue Dai , Loka Li , Chengqian Gao , Boyang Sun , Kun Zhang

We focus on the extension of bivariate causal learning methods into multivariate problem settings in a systematic manner via a novel framework. It is purposive to augment the scale to which bivariate causal discovery approaches can be…

统计方法学 · 统计学 2023-05-29 Hongyi Chen , Maurits Kaptein