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We introduce a new rotationally invariant viewing angle classification method for identifying, among a large number of Cryo-EM projection images, similar views without prior knowledge of the molecule. Our rotationally invariant features are…

生物大分子 · 定量生物学 2014-03-19 Zhizhen Zhao , Amit Singer

Tomography is an imaging technique that works by reconstructing a scene from acquired data in the form of line integrals of the imaging domain. A fundamental underlying assumption in the reconstruction procedure is the precise alignment of…

数值分析 · 数学 2018-07-13 Toby Sanders

Current 6D object pose estimation methods usually require a 3D model for each object. These methods also require additional training in order to incorporate new objects. As a result, they are difficult to scale to a large number of objects…

计算机视觉与模式识别 · 计算机科学 2020-06-15 Keunhong Park , Arsalan Mousavian , Yu Xiang , Dieter Fox

A common task in single particle electron cryomicroscopy (cryo-EM) is the rigid alignment of images and/or volumes. In the context of images, a rigid alignment involves estimating the inner-product between one image of $N\times N$ pixels…

数值分析 · 数学 2022-12-07 Aaditya V. Rangan

Motivation: Cellular Electron CryoTomography (CECT) is an emerging 3D imaging technique that visualizes subcellular organization of single cells at submolecular resolution and in near-native state. CECT captures large numbers of…

定量方法 · 定量生物学 2018-05-16 Yixiu Zhao , Xiangrui Zeng , Qiang Guo , Min Xu

We presented a new 3D refinement method for Cryo-EM single particle analysis which can improve the resolution of final electron density map in this paper. We proposed to enforce both sparsity and smoothness to improve the regularity of…

图像与视频处理 · 电气工程与系统科学 2020-03-12 Zhenwei Luo

Accurate prediction of model rocket flight performance requires estimating aerodynamic parameters that are difficult to measure directly. Traditional approaches rely on computational fluid dynamics or empirical correlations, while…

机器学习 · 计算机科学 2025-12-30 Rohit Pandey , Rohan Pandey

Heterogeneous Face Recognition (HFR) addresses the challenge of matching face images across different sensing modalities, such as thermal to visible or near-infrared to visible, expanding the applicability of face recognition systems in…

计算机视觉与模式识别 · 计算机科学 2025-04-29 Anjith George , Sebastien Marcel

The sparse interferometric coverage of the Event Horizon Telescope (EHT) poses a significant challenge for both reconstruction and model fitting of black-hole images. PRIMO is a new principal components analysis-based algorithm for image…

高能天体物理现象 · 物理学 2023-02-15 Lia Medeiros , Dimitrios Psaltis , Tod R. Lauer , Feryal Ozel

Noninvasive reconstruction of cardiac electrical activity from surface electrocardiograms (ECG) involves solving an ill-posed inverse problem. Cardiac electrophysiological (EP) models have been used as important a priori knowledge to…

图像与视频处理 · 电气工程与系统科学 2019-05-14 Sandesh Ghimire , John L Sapp , Milan Horacek , Linwei Wang

Motivated by the problem of determining the atomic structure of macromolecules using single-particle cryo-electron microscopy (cryo-EM), we study the sample and computational complexities of the sparse multi-reference alignment (MRA) model:…

信息论 · 计算机科学 2021-09-27 Tamir Bendory , Oscar Mickelin , Amit Singer

Cryo-electron microscopy can now routinely deliver atomic resolution structures for a variety of biological systems. The relevance and value of these structures is directly related to their ability to help rationalize experimental…

In this paper we study the formal algebraic structure underlying the intrinsic classification algorithm, recently introduced by Hadani, Shkolnisky, Singer and Zhao, for classifying noisy projection images of similar viewing directions in…

表示论 · 数学 2011-04-07 Ronny Hadani , Amit Singer

Recovering camera poses from a set of images is a foundational task in 3D computer vision, which powers key applications such as 3D scene/object reconstructions. Classic methods often depend on feature correspondence, such as keypoints,…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Hao Tang , Weiyao Wang , Pierre Gleize , Matt Feiszli

There is a clear need for developments in characterisation techniques that provide detailed information about structure-function relationships in biology. Using electron microscopy to achieve high resolution while maintaining a broad field…

定量方法 · 定量生物学 2023-09-12 Chen Huang , Judy S. Kim , Angus I. Kirkland

Cryo-Electron Microscopy (cryo-EM) has become an extremely powerful method for resolving structural details of large biomolecular complexes. However, challenging problems in single-particle methods remain open because of (1) the low…

We propose an adaptive learning procedure to learn patch-based image priors for image denoising. The new algorithm, called the Expectation-Maximization (EM) adaptation, takes a generic prior learned from a generic external database and…

计算机视觉与模式识别 · 计算机科学 2016-08-24 Enming Luo , Stanley H. Chan , Truong Q. Nguyen

Traditional sampling schemes often assume that the sampling locations are known. Motivated by the recent bioimaging technique known as cryogenic electron microscopy (cryoEM), we consider the problem of reconstructing an unknown 3D structure…

信号处理 · 电气工程与系统科学 2024-04-16 Renke Wang , Francien G. Bossema , Thierry Blu , Pier Luigi Dragotti

We propose embodied scene-aware human pose estimation where we estimate 3D poses based on a simulated agent's proprioception and scene awareness, along with external third-person observations. Unlike prior methods that often resort to…

计算机视觉与模式识别 · 计算机科学 2022-10-17 Zhengyi Luo , Shun Iwase , Ye Yuan , Kris Kitani

The problem of image restoration in cryo-EM entails correcting for the effects of the Contrast Transfer Function (CTF) and noise. Popular methods for image restoration include `phase flipping', which corrects only for the Fourier phases but…

计算机视觉与模式识别 · 计算机科学 2016-04-29 Tejal Bhamre , Teng Zhang , Amit Singer