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The brain's structural connectome supports signal propagation between neuronal elements, shaping diverse coactivation patterns that can be captured as functional connectivity. While the link between structure and function remains an ongoing…

神经元与认知 · 定量生物学 2022-07-11 Yaqian Yang , Zhiming Zheng , Longzhao Liu , Hongwei Zheng , Yi Zhen , Yi Zheng , Xin Wang , Shaoting Tang

Most generally, dynamic functional connectivity (FC) refers to the non-instantaneous couplings across timeseries from a set of brain areas, here as measured by fMRI. This is in contrast to static FC, which is defined as purely instantaneous…

神经元与认知 · 定量生物学 2023-01-10 Christine Ahrends , Diego Vidaurre

In mapping the human structural connectome, we are in a very fortunate situation: one can compute and compare graphs, describing the cerebral connections between the very same, anatomically identified small regions of the gray matter among…

神经元与认知 · 定量生物学 2017-12-01 Mate Fellner , Balint Varga , Vince Grolmusz

In recent years, graph neural networks (GNNs) have been widely applied in the analysis of brain fMRI, yet defining the connectivity between ROIs remains a challenge in noisy fMRI data. Among all approaches, Functional Connectome (FC) is the…

机器学习 · 计算机科学 2025-04-09 Jiyao Wang , Nicha C. Dvornek , Peiyu Duan , Lawrence H. Staib , Pamela Ventola , James S. Duncan

The evaluation of the individual 'fingerprint' of a human functional connectome (FC) is becoming a promising avenue for neuroscientific research, due to its enormous potential inherent to drawing single subject inferences from functional…

神经元与认知 · 定量生物学 2018-04-13 Enrico Amico , Joaquín Goñi

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

医学物理 · 物理学 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

神经元与认知 · 定量生物学 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

Benchmarking the hundreds of functional connectivity (FC) modeling methods on large-scale fMRI datasets is critical for reproducible neuroscience. However, the combinatorial explosion of model-data pairings makes exhaustive evaluation…

机器学习 · 计算机科学 2026-02-06 Ling Zhan , Zhen Li , Junjie Huang , Tao Jia

Functional connectome extends the anatomical connectome by capturing the relations between neurons according to their activity and interactions. When these relations are causal, the functional connectome maps how neural activity flows…

神经元与认知 · 定量生物学 2020-11-10 Rahul Biswas , Eli Shlizerman

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Understanding how distributed brain regions coordinate to produce behavior requires models that are both predictive and interpretable. We introduce Behavior-Adaptive Connectivity Estimation (BACE), an end-to-end framework that learns…

神经元与认知 · 定量生物学 2025-10-27 Mehrnaz Asadi , Sina Javadzadeh , Rahil Soroushmojdehi , S. Alireza Seyyed Mousavi , Terence D. Sanger

The white-matter (micro-)structural architecture of the brain promotes synchrony among neuronal populations, giving rise to richly patterned functional connections. A fundamental problem for systems neuroscience is determining the best way…

神经元与认知 · 定量生物学 2022-11-15 Yueting Li , Qingyue Wei , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao

In order to understand the complex cognitive functions of the human brain, it is essential to study the structural connectome, i.e., the wiring of different brain regions to each other through axonal pathways. However, the high degree of…

神经元与认知 · 定量生物学 2021-01-25 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

Advances in data analysis and machine learning have revolutionized the study of brain signatures using fMRI, enabling non-invasive exploration of cognition and behavior through individual neural patterns. Functional connectivity (FC), which…

图像与视频处理 · 电气工程与系统科学 2025-10-31 Yashaswini , Sanjay Ghosh

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

Integrating structural and functional connectomes remains challenging because their relationship is non-linear and organized over nested modular hierarchies. We propose a hierarchical multiscale structure-function coupling framework for…

Predicting behavioral variables from neuroimaging modalities such as magnetic resonance imaging (MRI) has the potential to allow the development of neuroimaging biomarkers of mental and neurological disorders. A crucial processing step to…

神经元与认知 · 定量生物学 2025-07-29 Mikkel Schöttner Sieler , Thomas A. W. Bolton , Jagruti Patel , Patric Hagmann

Functional magnetic resonance imaging (fMRI) data is characterized by its complexity and high--dimensionality, encompassing signals from various regions of interests (ROIs) that exhibit intricate correlations. Analyzing fMRI data directly…

应用统计 · 统计学 2024-01-18 Yeseul Jeon , Jeong-Jae Kim , SuMin Yu , Junggu Choi , Sanghoon Han

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

机器学习 · 统计学 2015-03-02 Shaurabh Nandy , Richard M. Golden

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

机器学习 · 计算机科学 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé