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We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

神经元与认知 · 定量生物学 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

Although modern imaging technologies allow us to study connectivity between two distinct brain regions in-vivo, an in-depth understanding of how anatomical structure supports brain function and how spontaneous functional fluctuations emerge…

神经元与认知 · 定量生物学 2024-10-29 Ziquan Wei , Tingting Dan , Jiaqi Ding , Guorong Wu

Unraveling how macroscopic cognitive phenotypes emerge from microscopic neuronal connectivity remains one of the core pursuits of neuroscience. To this end, researchers typically leverage multi-modal information from structural connectivity…

人工智能 · 计算机科学 2026-02-03 Tianhao Huang , Guanghui Min , Zhenyu Lei , Aiying Zhang , Chen Chen

Finding the common structural brain connectivity network for a given population is an open problem, crucial for current neuro-science. Recent evidence suggests there's a tightly connected network shared between humans. Obtaining this…

神经元与认知 · 定量生物学 2017-01-10 Nahuel Lascano , Guillermo Gallardo , Rachid Deriche , Dorian Mazauric , Demian Wassermann

This paper studies change-points in human brain functional connectivity (FC) and seeks patterns that are common across multiple subjects under identical external stimulus. FC relates to the similarity of fMRI responses across different…

神经元与认知 · 定量生物学 2020-03-05 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Functional connectivity (FC) as derived from fMRI has emerged as a pivotal tool in elucidating the intricacies of various psychiatric disorders and delineating the neural pathways that underpin cognitive and behavioral dynamics inherent to…

神经元与认知 · 定量生物学 2024-01-22 Gang Qu , Anton Orlichenko , Junqi Wang , Gemeng Zhang , Li Xiao , Aiying Zhang , Zhengming Ding , Yu-Ping Wang

In recent years, there has been strong interest in neuroscience studies to investigate brain organization through networks of brain regions that demonstrate strong functional connectivity (FC). These networks are extracted from observed…

应用统计 · 统计学 2017-03-14 Phebe Brenne Kemmer , F. DuBois Bowman , Helen Mayberg , Ying Guo

One of the crucial questions in neuroscience is how a rich functional repertoire of brain states relates to its underlying structural organization. How to study the associations between these structural and functional layers is an open…

神经元与认知 · 定量生物学 2018-02-22 Enrico Amico , Joaquín Goñi

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

统计方法学 · 统计学 2022-12-06 Arkaprava Roy

A key question in modern neuroscience is how cognitive changes in a human brain can be quantified and captured by functional connectomes (FC) . A systematic approach to measure pairwise functional distance at different brain states is…

神经元与认知 · 定量生物学 2018-09-26 Enrico Amico , Alex Arenas , Joaquin Goni

The relationship of network structure and dynamics is one of most extensively investigated problems in the theory of complex systems of the last years. Understanding this relationship is of relevance to a range of disciplines -- from…

Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

神经元与认知 · 定量生物学 2013-04-16 Gaël Varoquaux , R. C. Craddock

Examining task-free functional connectivity (FC) in the human brain offers insights on how spontaneous integration and segregation of information relate to human cognition, and how this organization may be altered in different conditions,…

The human connectome has been widely studied over the past decade. A principal finding is that it can be decomposed into communities of densely interconnected brain regions. This result, however, may be limited methodologically. Past…

Mapping from functional connectivity (FC) to structural connectivity (SC) can facilitate multimodal brain network fusion and discover potential biomarkers for clinical implications. However, it is challenging to directly bridge the reliable…

计算机视觉与模式识别 · 计算机科学 2026-04-01 Qiankun Zuo , Bangjun Lei , Wanyu Qiu , Changhong Jing , Jin Hong , Shuqiang Wang

Elucidating the intricate relationship between brain structure and function, both in healthy and pathological conditions, is a key challenge for modern neuroscience. Recent technical and methodological progress in neuroimaging has helped…

The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…

统计方法学 · 统计学 2022-11-03 Didong Li , Phuc Nguyen , Zhengwu Zhang , David B Dunson

The characterisation of the brain as a "connectome", in which the connections are represented by correlational values across timeseries and as summary measures derived from graph theory analyses, has been very popular in the last years.…

机器学习 · 计算机科学 2020-03-13 Tiago Azevedo , Luca Passamonti , Pietro Liò , Nicola Toschi

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…

统计计算 · 统计学 2023-08-11 William Consagra , Martin Cole , Xing Qiu , Zhengwu Zhang

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

神经元与认知 · 定量生物学 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang