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Variable selection for Gaussian process models is often done using automatic relevance determination, which uses the inverse length-scale parameter of each input variable as a proxy for variable relevance. This implicitly determined…

统计方法学 · 统计学 2019-04-24 Topi Paananen , Juho Piironen , Michael Riis Andersen , Aki Vehtari

In high-dimensional survival analysis, effective variable selection is crucial for both model interpretation and predictive performance. This paper investigates Cox regression with lasso and adaptive lasso penalties in genomic datasets…

统计方法学 · 统计学 2025-07-02 Pilar González-Barquero , Rosa E. Lillo , Álvaro Méndez-Civieta

Several gene-based association tests for time-to-event traits have been proposed recently, to detect whether a gene region (containing multiple variants), as a set, is associated with the survival outcome. However, for bivariate survival…

应用统计 · 统计学 2019-04-03 Yue Wei , Yi Liu , Wei Chen , Ying Ding

This paper considers the problem of robust adaptive efficient estimating of a periodic function in a continuous time regression model with the dependent noises given by a general square integrable semimartingale with a conditionally…

统计理论 · 数学 2019-09-24 Evgeny Pchelintsev , Serguei Pergamenshchikov

Joint models are well suited to modelling linked data from laboratories and health registers. However, there are few examples of joint models that allow for (a) multiple markers, (b) multiple survival outcomes (including terminal events,…

We consider parameter estimation, hypothesis testing and variable selection for partially time-varying coefficient models. Our asymptotic theory has the useful feature that it can allow dependent, nonstationary error and covariate…

统计理论 · 数学 2012-08-20 Ting Zhang , Wei Biao Wu

Distributional regression is extended to Gaussian response vectors of dimension greater than two by parameterizing the covariance matrix $\Sigma$ of the response distribution using the entries of its Cholesky decomposition. The more common…

统计方法学 · 统计学 2025-10-07 Thomas Muschinski , Georg J. Mayr , Thorsten Simon , Nikolaus Umlauf , Achim Zeileis

Latent variable models are popularly used to measure latent factors (e.g., abilities and personalities) from large-scale assessment data. Beyond understanding these latent factors, the covariate effect on responses controlling for latent…

统计方法学 · 统计学 2026-01-12 Jing Ouyang , Chengyu Cui , Kean Ming Tan , Gongjun Xu

Sparse regression is frequently employed in diverse scientific settings as a feature selection method. A pervasive aspect of scientific data that hampers both feature selection and estimation is the presence of strong correlations between…

统计方法学 · 统计学 2021-03-25 Ankit Kumar , Sharmodeep Bhattacharyya , Kristofer Bouchard

Objective: In randomized clinical trials, prediction models can be used to explore the relationships between patients' variables (e.g., clinical, pathological, or lifestyle variables, and also biomarker or genomic data) and treatment effect…

定量方法 · 定量生物学 2026-02-03 Elvire Roblin , Paul-Henry Cournède , Stefan Michiels

Background: The hazard ratio of the Cox proportional hazards model is widely used in randomized controlled trials to assess treatment effects. However, two properties of the hazard ratio including the non-collapsibility and built-in…

统计方法学 · 统计学 2024-01-17 Helen Bian , Menglan Pang , Guanbo Wang , Zihang Lu

Regression analyses based on transformations of cumulative incidence functions are often adopted when modeling and testing for treatment effects in clinical trial settings involving competing and semi-competing risks. Common frameworks…

统计方法学 · 统计学 2024-01-11 Alexandra Bühler , Richard J Cook , Jerald F Lawless

In this paper, we expand the methodology presented in Mertens et. al (2020, Biometrical Journal) to the study of life-time (survival) outcome which is subject to censoring and when imputation is used to account for missing values. We…

统计方法学 · 统计学 2021-05-06 Bart J. A. Mertens

Complex-valued signals are used in the modeling of many systems in engineering and science, hence being of fundamental interest. Often, random complex-valued signals are considered to be proper. A proper complex random variable or process…

Assuming some regression model, it is common to study the conditional distribution of survival given covariates. Here, we consider the impact of further conditioning, specifically conditioning on a marginal survival function, known or…

应用统计 · 统计学 2016-10-11 Roxane Duroux , Cécile Chauvel , John O'Quigley

Motivated by multi-center biomedical studies that cannot share individual data due to privacy and ownership concerns, we develop communication-efficient iterative distributed algorithms for estimation and inference in the high-dimensional…

统计方法学 · 统计学 2024-06-25 Pierre Bayle , Jianqing Fan , Zhipeng Lou

Bayesian nonparametric regression under a rescaled Gaussian process prior offers smoothness-adaptive function estimation with near minimax-optimal error rates. Hierarchical extensions of this approach, equipped with stochastic variable…

统计理论 · 数学 2020-12-15 Sheng Jiang , Surya T. Tokdar

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

统计方法学 · 统计学 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

Cox's proportional hazards model is one of the most popular statistical models to evaluate associations of exposure with a censored failure time outcome. When confounding factors are not fully observed, the exposure hazard ratio estimated…

统计方法学 · 统计学 2022-01-04 Linbo Wang , Eric Tchetgen Tchetgen , Torben Martinussen , Stijn Vansteelandt

In this paper, we make an experimental comparison of semi-parametric (Cox proportional hazards model, Aalen's additive regression model), parametric (Weibull AFT model), and machine learning models (Random Survival Forest, Gradient Boosting…

机器学习 · 计算机科学 2020-03-20 Camila Fernandez , Chung Shue Chen , Pierre Gaillard , Alonso Silva