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Recent advances in molecular and genetic research have identified a diverse range of brain tumor sub-types, shedding light on differences in their molecular mechanisms, heterogeneity, and origins. The present study performs whole-brain…

神经元与认知 · 定量生物学 2024-07-26 Debanjali Bhattacharya , Ninad Aithal , Manish Jayswal , Neelam Sinha

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

统计方法学 · 统计学 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

神经元与认知 · 定量生物学 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Structure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics…

神经元与认知 · 定量生物学 2008-08-27 Marcus Kaiser , Robert Martin , Peter Andras , Malcolm P. Young

Today the human brain can be modeled as a graph where nodes represent different regions and links stand for statistical interactions between their activities as recorded by different neuroimaging techniques. Empirical studies have lead to…

神经元与认知 · 定量生物学 2017-11-01 J. H. Martínez , J. M. Buldú , D. Papo , F. De Vico Fallani , M. Chavez

Functional connectivity of cognitive tasks allows researchers to analyse the interaction mapping occurring between different regions of the brain using electroencephalography (EEG) signals. Standard practice in functional connectivity…

人机交互 · 计算机科学 2019-07-23 Saugat Bhattacharyya , Mitsuhiro Hayashibe

High-throughput methods for yielding the set of connections in a neural system, the connectome, are now being developed. This tutorial describes ways to analyze the topological and spatial organization of the connectome at the macroscopic…

神经元与认知 · 定量生物学 2011-12-23 Marcus Kaiser

Functional magnetic resonance imaging (fMRI) functional connectivity between brain regions is often computed using parcellations defined by functional or structural atlases. Typically, some kind of voxel averaging is performed to obtain a…

Data-driven brain parcellations aim to provide a more accurate representation of an individual's functional connectivity, since they are able to capture individual variability that arises due to development or disease. This renders…

神经元与认知 · 定量生物学 2017-03-30 Sofia Ira Ktena , Salim Arslan , Sarah Parisot , Daniel Rueckert

The behavior of many complex systems is determined by a core of densely interconnected units. While many methods are available to identify the core of a network when connections between nodes are all of the same type, a principled approach…

神经元与认知 · 定量生物学 2018-09-14 Federico Battiston , Jeremy Guillon , Mario Chavez , Vito Latora , Fabrizio De Vico Fallani

Connectomics is a field of neuroscience that analyzes neuronal connections. A connectome is a complete map of a neuronal system, comprising all neuronal connections between its structures. The term "connectome" is close to the word "genome"…

Mammalian whole-brain connectomes are a foundational ingredient for holistic understanding of brains. Indeed, imaging connectomes at sufficient resolution to densely reconstruct cellular morphology and synapses represents a longstanding…

神经元与认知 · 定量生物学 2025-02-03 Logan Thrasher Collins , Todd Huffman , Randal Koene

Objective: The coupling between neuronal populations and its magnitude have been shown to be informative for various clinical applications. One method to estimate brain connectivity is with electroencephalography (EEG) from which the…

计算工程、金融与科学 · 计算机科学 2017-05-08 Loukianos Spyrou , Mario Parra , Javier Escudero

In cognitive network neuroscience, the connectivity and community structure of the brain network is related to cognition. Much of this research has focused on two measures of connectivity - modularity and flexibility - which frequently have…

神经元与认知 · 定量生物学 2017-11-28 Aurora I. Ramos-Nuñez , Simon Fischer-Baum , Randi Martin , Qiuhai Yue , Fengdan Ye , Michael W. Deem

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

The human brain is a complex network comprised of functionally and anatomically interconnected brain regions. A growing number of studies have suggested that empirical estimates of brain networks may be useful for discovery of biomarkers of…

神经元与认知 · 定量生物学 2022-11-15 Andrew Hannum , Mario A. Lopez , Saúl A. Blanco , Richard F. Betzel

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

应用统计 · 统计学 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

As the field of connectomics has matured, it has expanded from mapping the existence of connections between brain components to measuring the strength of connections. This information is increasingly accessible via methodologies such as…

神经元与认知 · 定量生物学 2021-03-30 Daniel Graham

Complex functional brain network analyses have exploded over the last eight years, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has…

统计方法学 · 统计学 2013-10-28 Sean L. Simpson , F. DuBois Bowman , Paul J. Laurienti

Structural and functional neuroimaging modalities provide complementary windows into brain organization: structural imaging characterizes neural tissue anatomy and microstructure, while functional imaging captures dynamic patterns of neural…

统计方法学 · 统计学 2026-03-24 Sakul Mahat , Sharmistha Guha , Jessica Bernard