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相关论文: Artificial Intelligence for In Silico Clinical Tri…

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Hardly any other area of research has recently attracted as much attention as machine learning (ML) through the rapid advances in artificial intelligence (AI). This publication provides a short introduction to practical concepts and methods…

综合经济学 · 经济学 2020-12-17 Ali R. Baghirzade

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

Artificial Intelligence (AI) is making a significant impact in multiple areas like medical, military, industrial, domestic, law, arts as AI is capable to perform several roles such as managing smart factories, driving autonomous vehicles,…

软件工程 · 计算机科学 2022-01-17 Zubair Khaliq , Sheikh Umar Farooq , Dawood Ashraf Khan

In the emerging era of big data, larger available clinical datasets and computational advances have sparked a massive interest in machine learning-based approaches. The number of manuscripts related to machine learning or artificial…

机器学习 · 统计学 2020-06-29 Julius M. Kernbach , Victor E. Staartjes

Clinical trials constitute a critical yet exceptionally challenging and costly stage of drug development (\$2.6B per drug), where protocols are encoded as complex natural language documents, motivating the use of AI systems beyond manual…

人工智能 · 计算机科学 2026-04-06 Sixue Xing , Kerui Wu , Xuanye Xia , Meng Jiang , Jintai Chen , Tianfan Fu

Purpose of review: Artificial intelligence (AI) has become popular in medical applications, specifically as a clinical support tool for computer-aided diagnosis. These tools are typically employed on medical data (i.e., image, molecular…

机器学习 · 计算机科学 2022-06-08 Ahmad Chaddad , Yousef Katib , Lama Hassan

Artificial intelligence (AI) has been transforming the practice of drug discovery in the past decade. Various AI techniques have been used in a wide range of applications, such as virtual screening and drug design. In this survey, we first…

机器学习 · 计算机科学 2021-11-03 Jianyuan Deng , Zhibo Yang , Iwao Ojima , Dimitris Samaras , Fusheng Wang

Drug discovery is adapting to novel technologies such as data science, informatics, and artificial intelligence (AI) to accelerate effective treatment development while reducing costs and animal experiments. AI is transforming drug…

人工智能 · 计算机科学 2023-07-14 Catrin Hasselgren , Tudor I. Oprea

Causal machine learning (ML) offers flexible, data-driven methods for predicting treatment outcomes including efficacy and toxicity, thereby supporting the assessment and safety of drugs. A key benefit of causal ML is that it allows for…

The introduction of computational models in cardiovascular sciences has been progressively bringing new and unique tools for the investigation of the physiopathology. Together with the dramatic improvement of imaging and measuring devices…

FDA has been promoting enrollment practices that could enhance the diversity of clinical trial populations, through broadening eligibility criteria. However, how to broaden eligibility remains a significant challenge. We propose an AI…

计算与语言 · 计算机科学 2021-09-08 Xiong Liu , Cheng Shi , Uday Deore , Yingbo Wang , Myah Tran , Iya Khalil , Murthy Devarakonda

Clinical trials are crucial for assessing new treatments; however, recruitment challenges - such as limited awareness, complex eligibility criteria, and referral barriers - hinder their success. With the growth of online platforms, patients…

信息检索 · 计算机科学 2025-04-30 Joey Chan , Qiao Jin , Nicholas Wan , Charalampos S. Floudas , Elisabetta Xue , Zhiyong Lu

Significant advancements have been made in recent years to optimize patient recruitment for clinical trials, however, improved methods for patient recruitment prediction are needed to support trial site selection and to estimate appropriate…

机器学习 · 计算机科学 2021-11-16 Jingshu Liu , Patricia J Allen , Luke Benz , Daniel Blickstein , Evon Okidi , Xiao Shi

A key challenge for the development and deployment of artificial intelligence (AI) solutions in radiology is solving the associated data limitations. Obtaining sufficient and representative patient datasets with appropriate annotations may…

图像与视频处理 · 电气工程与系统科学 2024-07-03 Elena Sizikova , Andreu Badal , Jana G. Delfino , Miguel Lago , Brandon Nelson , Niloufar Saharkhiz , Berkman Sahiner , Ghada Zamzmi , Aldo Badano

Artificial intelligence (AI) has sparked immense interest in drug discovery, but most current approaches only digitize existing high-throughput experiments. They remain constrained by conventional pipelines. As a result, they do not address…

计算机与社会 · 计算机科学 2025-07-29 You Wu , Philip E. Bourne , Lei Xie

Since real-world legal experiments are often costly or infeasible, simulating legal societies with Artificial Intelligence (AI) systems provides an effective alternative for verifying and developing legal theory, as well as supporting legal…

人工智能 · 计算机科学 2025-10-29 Yiding Wang , Yuxuan Chen , Fanxu Meng , Xifan Chen , Xiaolei Yang , Muhan Zhang

Artificial intelligence (AI) raises expectations of substantial increases in rates of technological and scientific progress, but such anticipations are often not connected to detailed ground-level studies of AI use in innovation processes.…

计算机与社会 · 计算机科学 2025-11-21 John P. Nelson , Olajide Olugbade , Philip Shapira , Justin B. Biddle

Traditional drug discovery is a long, expensive, and complex process. Advances in Artificial Intelligence (AI) and Machine Learning (ML) are beginning to change this narrative. Here, we provide a comprehensive overview of different AI and…

As ultracold atom experiments become highly controlled and scalable quantum simulators, they require sophisticated control over high-dimensional parameter spaces and generate increasingly complex measurement data that need to be analyzed…

量子气体 · 物理学 2025-09-11 Henning Schlömer , Annabelle Bohrdt

Artificial intelligence (AI) algorithms using deep learning have advanced the classification of skin disease images; however these algorithms have been mostly applied "in silico" and not validated clinically. Most dermatology AI algorithms…

计算机视觉与模式识别 · 计算机科学 2021-05-24 Roxana Daneshjou , Carrie Kovarik , Justin M Ko