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A transversal study of the pitch variability of parkinsonian voices in read speech is presented. 30 patients suffering from Parkinson's disease (PD) and 32 healthy speakers were recorded while reading a text without voiceless phonemes. The…

音频与语音处理 · 电气工程与系统科学 2024-02-12 Pablo Rodriguez-Perez , Ruben Fraile , Miguel Garcia-Escrig , Nicolas Saenz-Lechon , Juana M. Gutierrez-Arriola , Victor Osma-Ruiz

In this paper, we study a novel problem: "automatic prescription recommendation for PD patients." To realize this goal, we first build a dataset by collecting 1) symptoms of PD patients, and 2) their prescription drug provided by…

机器学习 · 计算机科学 2020-08-03 Yinghuan Shi , Wanqi Yang , Kim-Han Thung , Hao Wang , Yang Gao , Yang Pan , Li Zhang , Dinggang Shen

Speech enhancement techniques based on deep learning have brought significant improvement on speech quality and intelligibility. Nevertheless, a large gain in speech quality measured by objective metrics, such as perceptual evaluation of…

音频与语音处理 · 电气工程与系统科学 2020-07-06 Bo Wu , Meng Yu , Lianwu Chen , Yong Xu , Chao Weng , Dan Su , Dong Yu

Dysarthric speech reconstruction is challenging due to its pathological sound patterns. Preserving speaker identity, especially without access to normal speech, is a key challenge. Our proposed approach uses contrastive learning to extract…

音频与语音处理 · 电气工程与系统科学 2024-10-08 Keshvari Fatemeh , Mahdian Toroghi Rahil , Zareian Hassan

Hypernasality is a common characteristic symptom across many motor-speech disorders. For voiced sounds, hypernasality introduces an additional resonance in the lower frequencies and, for unvoiced sounds, there is reduced articulatory…

音频与语音处理 · 电气工程与系统科学 2020-09-14 Michael Saxon , Ayush Tripathi , Yishan Jiao , Julie Liss , Visar Berisha

Speech disorders often occur at the early stage of Parkinson's disease (PD). The speech impairments could be indicators of the disorder for early diagnosis, while motor symptoms are not obvious. In this study, we constructed a new speech…

音频与语音处理 · 电气工程与系统科学 2021-06-01 Hao Fang , Chen Gong , Chen Zhang , Yanan Sui , Luming Li

We propose a representation learning framework for medical diagnosis domain. It is based on heterogeneous network-based model of diagnostic data as well as modified metapath2vec algorithm for learning latent node representation. We compare…

机器学习 · 计算机科学 2020-01-24 Karol Antczak

Diffusion models have shown a great ability at bridging the performance gap between predictive and generative approaches for speech enhancement. We have shown that they may even outperform their predictive counterparts for non-additive…

音频与语音处理 · 电气工程与系统科学 2024-03-13 Jean-Marie Lemercier , Julius Richter , Simon Welker , Timo Gerkmann

Paralinguistic properties of speech are essential in analyzing and choosing optimal treatment options for patients with speech disorders. However, automatic modeling of these characteristics is difficult due to the lack of labeled speech…

音频与语音处理 · 电气工程与系统科学 2025-09-25 Jenthe Thienpondt , Geoffroy Vanderreydt , Abdessalem Hammami , Kris Demuynck

We present a probabilistic programmed deep kernel learning approach to personalized, predictive modeling of neurodegenerative diseases. Our analysis considers a spectrum of neural and symbolic machine learning approaches, which we assess…

机器学习 · 计算机科学 2021-01-13 Alexander Lavin

Acoustic models using probabilistic linear discriminant analysis (PLDA) capture the correlations within feature vectors using subspaces which do not vastly expand the model. This allows high dimensional and correlated feature spaces to be…

计算与语言 · 计算机科学 2015-06-23 Liang Lu , Steve Renals

Dysarthria is a speech disorder that hinders communication due to difficulties in articulating words. Detection of dysarthria is important for several reasons as it can be used to develop a treatment plan and help improve a person's quality…

Deep learning has been widely applied in neuroimaging, including predicting brain-phenotype relationships from magnetic resonance imaging (MRI) volumes. MRI data usually requires extensive preprocessing prior to modeling, but variation…

机器学习 · 计算机科学 2023-10-17 Xinhui Li , Alex Fedorov , Mrinal Mathur , Anees Abrol , Gregory Kiar , Sergey Plis , Vince Calhoun

Diagnosing autism spectrum disorder (ASD) by identifying abnormal speech patterns from examiner-patient dialogues presents significant challenges due to the subtle and diverse manifestations of speech-related symptoms in affected…

声音 · 计算机科学 2024-05-09 Chuanbo Hu , Jacob Thrasher , Wenqi Li , Mindi Ruan , Xiangxu Yu , Lynn K Paul , Shuo Wang , Xin Li

Large-scale end-to-end models such as Whisper have shown strong performance on diverse speech tasks, but their internal behavior on pathological speech remains poorly understood. Understanding how dysarthric speech is represented across…

音频与语音处理 · 电气工程与系统科学 2025-10-07 Zhengjun Yue , Devendra Kayande , Zoran Cvetkovic , Erfan Loweimi

Recently, hybrid systems of clustering and neural diarization models have been successfully applied in multi-party meeting analysis. However, current models always treat overlapped speaker diarization as a multi-label classification…

声音 · 计算机科学 2022-11-21 Zhihao Du , Shiliang Zhang , Siqi Zheng , Zhijie Yan

In the past few years, there are several researches on Parkinson's disease (PD) recognition using single-photon emission computed tomography (SPECT) images with deep learning (DL) approach. However, the DL model's complexity usually results…

图像与视频处理 · 电气工程与系统科学 2021-05-05 Theerasarn Pianpanit , Sermkiat Lolak , Phattarapong Sawangjai , Thapanun Sudhawiyangkul , Theerawit Wilaiprasitporn

Patient-reported outcomes (PROs) directly collected from cancer patients being treated with radiation therapy play a vital role in assisting clinicians in counseling patients regarding likely toxicities. Precise prediction and evaluation of…

机器学习 · 计算机科学 2024-11-19 Yang Yan , Zhong Chen , Cai Xu , Xinglei Shen , Jay Shiao , John Einck , Ronald C Chen , Hao Gao

Large audio and language models have recently demonstrated zero-shot reasoning capabilities across various domains. However, it remains unclear how the form of audio input, whether handcrafted acoustic features extracted from speech or the…

声音 · 计算机科学 2026-05-26 Muhammad Ashad Kabir , Sirajam Munira

Speech enhancement in hearing aids remains a difficult task in nonstationary acoustic environments, mainly because current signal processing algorithms rely on fixed, manually tuned parameters that cannot adapt in situ to different users or…