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Accurate prediction of protein-ligand binding affinities is crucial for drug development. Recent advances in machine learning show promising results on this task. However, these methods typically rely heavily on labeled data, which can be…

机器学习 · 计算机科学 2024-06-13 Meng Liu , Saee Gopal Paliwal

The goal of multi-task learning is to learn diverse tasks within a single unified network. As each task has its own unique objective function, conflicts emerge during training, resulting in negative transfer among them. Earlier research…

机器学习 · 计算机科学 2024-06-06 Wooseong Jeong , Kuk-Jin Yoon

Multi-task learning (MTL) is an effective method for learning related tasks, but designing MTL models necessitates deciding which and how many parameters should be task-specific, as opposed to shared between tasks. We investigate this issue…

计算与语言 · 计算机科学 2020-02-18 Phil Crone

Multi-task learning (MTL) is a supervised learning paradigm in which the prediction models for several related tasks are learned jointly to achieve better generalization performance. When there are only a few training examples per task, MTL…

机器学习 · 计算机科学 2017-06-07 Azad Naik , Anveshi Charuvaka , Huzefa Rangwala

Meta-learning has been proposed as a framework to address the challenging few-shot learning setting. The key idea is to leverage a large number of similar few-shot tasks in order to learn how to adapt a base-learner to a new task for which…

计算机视觉与模式识别 · 计算机科学 2019-04-10 Qianru Sun , Yaoyao Liu , Tat-Seng Chua , Bernt Schiele

Multi-task neural networks learn tasks simultaneously to improve individual task performance. There are three mechanisms of multi-task learning (MTL) which are explored here for the context of structural health monitoring (SHM): (i) the…

机器学习 · 计算机科学 2023-05-17 Sarah Bee , Lawrence Bull , Nikolas Dervilis , Keith Worden

Multi-Task Learning (MTL) aims to enhance the model generalization by sharing representations between related tasks for better performance. Typical MTL methods are jointly trained with the complete multitude of ground-truths for all tasks…

计算机视觉与模式识别 · 计算机科学 2021-10-15 Yufeng Wang , Yi-Hsuan Tsai , Wei-Chih Hung , Wenrui Ding , Shuo Liu , Ming-Hsuan Yang

Accurate house prediction is of great significance to various real estate stakeholders such as house owners, buyers, investors, and agents. We propose a location-centered prediction framework that differs from existing work in terms of data…

机器学习 · 计算机科学 2023-04-06 Guangliang Gao , Zhifeng Bao , Jie Cao , A. K. Qin , Timos Sellis , Zhiang Wu

Multi-task learning (MTL) is to learn one single model that performs multiple tasks for achieving good performance on all tasks and lower cost on computation. Learning such a model requires to jointly optimize losses of a set of tasks with…

计算机视觉与模式识别 · 计算机科学 2020-09-25 Wei-Hong Li , Hakan Bilen

Multi-task-learning(MTL) is a multi-target optimization task. Neural networks try to realize each target using a shared interpretative space within MTL. However, as the scale of datasets expands and the complexity of tasks increases,…

计算机视觉与模式识别 · 计算机科学 2024-10-08 Ruiyuan Zhang , Yuyao Chen , Yuchi Huo , Jiaxiang Liu , Dianbing Xi , Jie Liu , Chao Wu

Multitask learning (MTL) has become prominent for its ability to predict multiple tasks jointly, achieving better per-task performance with fewer parameters than single-task learning. Recently, decoder-focused architectures have…

计算机视觉与模式识别 · 计算机科学 2024-11-07 Dimitrios Sinodinos , Narges Armanfard

Recently, deep neural network (DNN)-based drug-target interaction (DTI) models were highlighted for their high accuracy with affordable computational costs. Yet, the models' insufficient generalization remains a challenging problem in the…

生物大分子 · 定量生物学 2021-12-14 Seokhyun Moon , Wonho Zhung , Soojung Yang , Jaechang Lim , Woo Youn Kim

Multi-task learning (MTL) has achieved remarkable success in natural language processing applications. In this work, we study a multi-task learning model with multiple decoders on varieties of biomedical and clinical natural language…

计算与语言 · 计算机科学 2020-05-07 Yifan Peng , Qingyu Chen , Zhiyong Lu

Simultaneous load forecasting across multiple entities (e.g., regions, buildings) is crucial for the efficient, reliable, and cost-effective operation of power systems. Accurate load forecasting is a challenging problem due to the inherent…

机器学习 · 计算机科学 2026-01-21 Onintze Zaballa , Verónica Álvarez , Santiago Mazuelas

Drug resistance is a major threat to the global health and a significant concern throughout the clinical treatment of diseases and drug development. The mutation in proteins that is related to drug binding is a common cause for adaptive…

定量方法 · 定量生物学 2022-05-18 Ziyi Yang , Zhaofeng Ye , Yijia Xiao , Changyu Hsieh , Shengyu Zhang

Multi-task learning (MTL) has become an essential machine learning tool for addressing multiple learning tasks simultaneously and has been effectively applied across fields such as healthcare, marketing, and biomedical research. However, to…

机器学习 · 统计学 2025-06-02 Yang Sui , Qi Xu , Yang Bai , Annie Qu

Multi-task learning (MTL) in materials science relies on the assumption that physically related properties share learnable representations. We challenge this assumption using a 54,028-sample metal alloy dataset exhibiting extreme task-level…

机器学习 · 计算机科学 2026-02-03 Sungwoo Kang

Accurate prediction of Drug-Target Affinity (DTA) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based deep learning methods avoid reliance on costly 3D…

机器学习 · 计算机科学 2025-11-03 Minghui Li , Yuanhang Wang , Peijin Guo , Wei Wan , Shengshan Hu , Shengqing Hu

Multitask learning (MTL) has recently gained a lot of popularity as a learning paradigm that can lead to improved per-task performance while also using fewer per-task model parameters compared to single task learning. One of the biggest…

计算机视觉与模式识别 · 计算机科学 2022-01-27 Dimitrios Sinodinos , Narges Armanfard

Meta-learning has emerged as an effective methodology to model several real-world tasks and problems due to its extraordinary effectiveness in the low-data regime. There are many scenarios ranging from the classification of rare diseases to…

机器学习 · 计算机科学 2023-12-29 Prabhat Agarwal , Shreya Singh