中文
相关论文

相关论文: MLT-LE: predicting drug-target binding affinity wi…

200 篇论文

The problem of learning simultaneously several related tasks has received considerable attention in several domains, especially in machine learning with the so-called multitask learning problem or learning to learn problem [1], [2].…

信号处理 · 电气工程与系统科学 2021-09-29 Roula Nassif , Stefan Vlaski , Cedric Richard , Jie Chen , Ali H. Sayed

Multi-task learning (MTL) has received considerable attention, and numerous deep learning applications benefit from MTL with multiple objectives. However, constructing multiple related tasks is difficult, and sometimes only a single task is…

计算机视觉与模式识别 · 计算机科学 2019-11-25 Tao Gui , Lizhi Qing , Qi Zhang , Jiacheng Ye , Hang Yan , Zichu Fei , Xuanjing Huang

Accurate prediction of the binding affinity between drugs and target proteins is a core task in computer-aided drug design. Existing deep learning methods tend to ignore the information of internal sub-structural features of drug molecules…

生物大分子 · 定量生物学 2025-04-04 Jiannuo Li , Lan Yao

Explainable ML for molecular toxicity prediction is a promising approach for efficient drug development and chemical safety. A predictive ML model of toxicity can reduce experimental cost and time while mitigating ethical concerns by…

We study and quantify the generalization patterns of multitask learning (MTL) models for sequence labeling tasks. MTL models are trained to optimize a set of related tasks jointly. Although multitask learning has achieved improved…

机器学习 · 计算机科学 2020-09-29 Gabriele Bettgenhäuser , Michael A. Hedderich , Dietrich Klakow

We investigate whether and where multi-task learning (MTL) can improve performance on NLP problems related to argumentation mining (AM), in particular argument component identification. Our results show that MTL performs particularly well…

计算与语言 · 计算机科学 2018-05-07 Claudia Schulz , Steffen Eger , Johannes Daxenberger , Tobias Kahse , Iryna Gurevych

Multi-task learning (MTL) aims at improving the generalization performance of several related tasks by leveraging useful information contained in them. However, in industrial scenarios, interpretability is always demanded, and the data of…

机器学习 · 计算机科学 2020-03-17 Ya-Lin Zhang , Longfei Li

This paper presents a novel method that allows a machine learning algorithm following the transformation-based learning paradigm \cite{brill95:tagging} to be applied to multiple classification tasks by training jointly and simultaneously on…

计算与语言 · 计算机科学 2007-05-23 Radu Florian , Grace Ngai

We propose a unified framework for adaptive routing in multitask, multimodal prediction settings where data heterogeneity and task interactions vary across samples. Motivated by applications in psychotherapy where structured assessments and…

Structure based ligand discovery is one of the most successful approaches for augmenting the drug discovery process. Currently, there is a notable shift towards machine learning (ML) methodologies to aid such procedures. Deep learning has…

机器学习 · 统计学 2018-06-12 Marta M. Stepniewska-Dziubinska , Piotr Zielenkiewicz , Pawel Siedlecki

Deep learning based models are used regularly in every applications nowadays. Generally we train a single model on a single task. However, we can train multiple tasks on a single model under multi-task learning settings. This provides us…

机器学习 · 计算机科学 2023-03-14 Aminul Huq , Mst Tasnim Pervin

Multi-task learning (MTL) aims to improve the performance of multiple related prediction tasks by leveraging useful information from them. Due to their flexibility and ability to reduce unknown coefficients substantially, the…

机器学习 · 计算机科学 2022-12-01 Yuzhao Zhang , Yifan Sun

Recently, a number of drug-therapy, disease, drug, and drug-target networks have been introduced. Here we suggest novel methods for network-based prediction of novel drug targets and for improvement of drug efficiency by analysing the…

分子网络 · 定量生物学 2008-07-31 Zoltan Spiro , Istvan A. Kovacs , Peter Csermely

Multi-task learning aims to learn multiple tasks jointly by exploiting their relatedness to improve the generalization performance for each task. Traditionally, to perform multi-task learning, one needs to centralize data from all the tasks…

机器学习 · 计算机科学 2017-06-21 Sulin Liu , Sinno Jialin Pan , Qirong Ho

Multi-task learning (MTL) is an efficient solution to solve multiple tasks simultaneously in order to get better speed and performance than handling each single-task in turn. The most current methods can be categorized as either: (i) hard…

计算机视觉与模式识别 · 计算机科学 2019-12-02 Yifan Liu , Bohan Zhuang , Chunhua Shen , Hao Chen , Wei Yin

Multi-Task Learning (MTL) plays a crucial role in real-world advertising applications such as recommender systems, aiming to achieve robust representations while minimizing resource consumption. MTL endeavors to simultaneously optimize…

信息检索 · 计算机科学 2024-06-06 Furkan Durmus , Hasan Saribas , Said Aldemir , Junyan Yang , Hakan Cevikalp

Multi-task learning (MTL) is a learning paradigm that enables the simultaneous training of multiple communicating algorithms. Although MTL has been successfully applied to ether regression or classification tasks alone, incorporating mixed…

Online learning with streaming data in a distributed and collaborative manner can be useful in a wide range of applications. This topic has been receiving considerable attention in recent years with emphasis on both single-task and…

多智能体系统 · 计算机科学 2017-04-26 Jie Chen , Cédric Richard , Ali H. Sayed

Multi-task learning (MTL) optimizes several learning tasks simultaneously and leverages their shared information to improve generalization and the prediction of the model for each task. Auxiliary tasks can be added to the main task to…

机器学习 · 计算机科学 2020-07-03 Partoo Vafaeikia , Khashayar Namdar , Farzad Khalvati

Typical multi-task learning (MTL) methods rely on architectural adjustments and a large trainable parameter set to jointly optimize over several tasks. However, when the number of tasks increases so do the complexity of the architectural…

计算机视觉与模式识别 · 计算机科学 2019-03-29 Gjorgji Strezoski , Nanne van Noord , Marcel Worring