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Generating positron emission tomography (PET) images from computed tomography (CT) scans via deep learning offers a promising pathway to reduce radiation exposure and costs associated with PET imaging, improving patient care and…

图像与视频处理 · 电气工程与系统科学 2026-02-16 Valerio Guarrasi , Francesco Di Feola , Rebecca Restivo , Lorenzo Tronchin , Paolo Soda

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…

计算机视觉与模式识别 · 计算机科学 2025-11-27 Xin Honga , Jie Lin , Minghui Wang

Digital twins, as precise digital representations of physical systems, have evolved from passive simulation tools into intelligent and autonomous entities through the integration of artificial intelligence technologies. This paper presents…

Magnetic resonance imaging of whole fetal body and placenta is limited by different sources of motion affecting the womb. Usual scanning techniques employ single-shot multi-slice sequences where anatomical information in different slices…

A cardiac digital twin is a virtual replica of a patient's heart for screening, diagnosis, prognosis, risk assessment, and treatment planning of cardiovascular diseases. This requires an anatomically accurate patient-specific 3D structural…

Cardiovascular disease, the leading cause of death globally, is an age-related disease. Understanding the morphological and functional changes of the heart during ageing is a key scientific question, the answer to which will help us define…

图像与视频处理 · 电气工程与系统科学 2022-10-11 Mengyun Qiao , Berke Doga Basaran , Huaqi Qiu , Shuo Wang , Yi Guo , Yuanyuan Wang , Paul M. Matthews , Daniel Rueckert , Wenjia Bai

Background: While deep learning technology, which has the capability of obtaining latent representations based on large-scale data, can be a potential solution for the discovery of a novel aging biomarker, existing deep learning methods for…

机器学习 · 计算机科学 2023-02-02 Seong-Eun Moon , Ji Won Yoon , Shinyoung Joo , Yoohyung Kim , Jae Hyun Bae , Seokho Yoon , Haanju Yoo , Young Min Cho

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

计算机视觉与模式识别 · 计算机科学 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

Synthetic longitudinal brain MRI simulates brain aging and would enable more efficient research on neurodevelopmental and neurodegenerative conditions. Synthetically generated, age-adjusted brain images could serve as valuable alternatives…

信号处理 · 电气工程与系统科学 2024-05-03 Anna Zapaishchykova , Benjamin H. Kann , Divyanshu Tak , Zezhong Ye , Daphne A. Haas-Kogan , Hugo J. W. L. Aerts

Heart diseases rank among the leading causes of global mortality, demonstrating a crucial need for early diagnosis and intervention. Most traditional electrocardiogram (ECG) based automated diagnosis methods are trained at population level,…

机器学习 · 计算机科学 2024-05-14 Yaojun Hu , Jintai Chen , Lianting Hu , Dantong Li , Jiahuan Yan , Haochao Ying , Huiying Liang , Jian Wu

We propose a digital twin approach to improve healthcare decision support systems with a combination of domain knowledge and data. Domain knowledge helps build decision thresholds that doctors can use to determine a risk or recommend a…

人工智能 · 计算机科学 2019-10-31 Dattaraj Jagdish Rao , Shraddha Mane

Using 3D CNNs on high resolution medical volumes is very computationally demanding, especially for large datasets like the UK Biobank which aims to scan 100,000 subjects. Here we demonstrate that using 2D CNNs on a few 2D projections…

图像与视频处理 · 电气工程与系统科学 2023-03-14 Johan Jönemo , Muhammad Usman Akbar , Robin Kämpe , J Paul Hamilton , Anders Eklund

Deep learning algorithms for predicting neuroimaging data have shown considerable promise in various applications. Prior work has demonstrated that deep learning models that take advantage of the data's 3D structure can outperform standard…

图像与视频处理 · 电气工程与系统科学 2023-03-07 Yuda Bi , Anees Abrol , Zening Fu , Jiayu Chen , Jingyu Liu , Vince Calhoun

Digital Twins technology is revolutionizing decision-making in scientific research by integrating models and simulations with real-time data. Unlike traditional Structural Health Monitoring methods, which rely on computationally intensive…

计算机视觉与模式识别 · 计算机科学 2024-10-10 Mehrdad Shafiei Dizaji

With the continuous advancement of technology, artificial intelligence has significantly impacted various fields, particularly healthcare. Generative models, a key AI technology, have revolutionized medical image generation, data analysis,…

机器学习 · 计算机科学 2024-10-10 Yuan Sun , Jorge Ortiz

This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

机器学习 · 计算机科学 2026-05-13 Zarrin Monirzadeh

Predicting individual cognitive decline in Alzheimer's disease (AD) is difficult due to the heterogeneity of disease progression. Reliable clinical tools require not only high accuracy but also fairness across demographics and robustness to…

人工智能 · 计算机科学 2026-04-27 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

In recent years, advances in neuroscience and artificial intelligence have paved the way for unprecedented opportunities for understanding the complexity of the brain and its emulation by computational systems. Cutting-edge advancements in…

神经元与认知 · 定量生物学 2024-04-19 Hui Xiong , Congying Chu , Lingzhong Fan , Ming Song , Jiaqi Zhang , Yawei Ma , Ruonan Zheng , Junyang Zhang , Zhengyi Yang , Tianzi Jiang

Normative aging trends of the brain can serve as an important reference in the assessment of neurological structural disorders. Such models are typically developed from longitudinal brain image data -- follow-up data of the same subject…

计算机视觉与模式识别 · 计算机科学 2021-06-29 Alphin J Thottupattu , Jayanthi Sivaswamy , Venkateswaran P. Krishnan

The generation of 3D models from real-world objects has often been accomplished through photogrammetry, i.e., by taking 2D photos from a variety of perspectives and then triangulating matched point-based features to create a textured mesh.…

计算机视觉与模式识别 · 计算机科学 2026-02-13 Jacob Rubinstein , Avi Donaty , Don Engel