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A prompt public health response to a new epidemic relies on the ability to monitor and predict its evolution in real time as data accumulate. The 2009 A/H1N1 outbreak in the UK revealed pandemic data as noisy, contaminated, potentially…

The complex interplay between population movements in space and non-homogeneous mixing patterns have so far hindered the fundamental understanding of the conditions for spatial invasion through a general theoretical framework. To address…

物理与社会 · 物理学 2014-01-21 Andrea Apolloni , Chiara Poletto , Jose' J. Ramasco , Pablo Jensen , Vittoria Colizza

Predicting popularity, or the total volume of information outbreaks, is an important subproblem for understanding collective behavior in networks. Each of the two main types of recent approaches to the problem, feature-driven and generative…

社会与信息网络 · 计算机科学 2016-08-31 Swapnil Mishra , Marian-Andrei Rizoiu , Lexing Xie

The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…

应用统计 · 统计学 2026-03-10 Anastasios Apsemidis , Nikolaos Demiris

The purpose of this study is to leverage modern technology (such as mobile or web apps in Beckman et al. (2014)) to enrich epidemiology data and infer the transmission of disease. Homogeneity related research on population level has been…

应用统计 · 统计学 2015-09-02 Kai Fan , Allison E. Aiello , Katherine A. Heller

In this manuscript we consider an age structured epidemic system modelling the dynamics of transmission of immunizing disease like Hepatitis B virus. Our model takes into account age as well as two classes of infected individuals (chronic…

偏微分方程分析 · 数学 2016-05-17 Yannick Tchaptchie Kouakep

Understanding how age-specific social contact patterns and susceptibility influence infectious disease transmission is crucial for accurate epidemic modeling. This study presents an eigenvector-based sensitivity analysis framework to…

种群与进化 · 定量生物学 2025-11-21 Evans Kiptoo Korir , Zsolt Vizi

Marked Temporal Point Processes (MTPPs) arise naturally in medical, social, commercial, and financial domains. However, existing Transformer-based methods mostly inject temporal information only via positional encodings, relying on shared…

机器学习 · 计算机科学 2026-03-25 Xinzi Tan , Kejian Zhang , Junhan Yu , Doudou Zhou

Parameter inference and state estimation in stochastic and partially observed biological systems remain major problems in mathematical biology. In this work, we introduce a two-dimensional lattice graph model for the spread of infectious…

定量方法 · 定量生物学 2026-05-29 Ihtisham Ul Haq , Serge Richard

Early outbreak data analysis is critical for informing about their potential impact and interventions. However, data obtained early in outbreaks are often sensitive and subject to strict privacy restrictions. Thus, federated analysis, which…

应用统计 · 统计学 2026-01-27 Simon Busch-Moreno , Moritz U. G. Kraemer

We develop theoretical equivalences between stochastic and deterministic models for populations of individual cells stratified by age. Specifically, we develop a hierarchical system of equations describing the full dynamics of an…

种群与进化 · 定量生物学 2022-06-29 Joshua C. Kynaston , Chris Guiver , Christian A. Yates

Working in the multi-type Galton-Watson branching-process framework we analyse the spread of a pandemic via a general multi-type random contact graph. Our model consists of several communities, and takes, as input, parameters that outline…

统计力学 · 物理学 2023-06-14 Dor Minzer , Yaron Oz , Muli Safra , Lior Wainstain

The Hawkes process (HP) has been widely applied to modeling self-exciting events including neuron spikes, earthquakes and tweets. To avoid designing parametric triggering kernel and to be able to quantify the prediction confidence, the…

机器学习 · 计算机科学 2021-02-05 Rui Zhang , Christian Walder , Marian-Andrei Rizoiu

We numerically address the stability analysis of linear age-structured population models with nonlocal diffusion, which arise naturally in describing dynamics of infectious diseases. Compared to Laplace diffusion, models with nonlocal…

数值分析 · 数学 2024-03-13 Dimitri Breda , Simone De Reggi , Rossana Vermiglio

We propose a deterministic compartmental model of infectious disease which considers the test-kits as an important ingredient for the suppression and mitigation of epidemics. A rigorous simulation (with analytical argument) is provided to…

物理与社会 · 物理学 2021-07-28 Subrata Ghosh , Abhishek Senapati , Joydev Chattopadhyay , Chittaranjan Hens , Dibakar Ghosh

Foundational marked temporal point process (MTPP) models, such as the Hawkes process, often use inexpressive model families in order to offer interpretable parameterizations of event data. On the other hand, neural MTPPs models forego this…

机器学习 · 统计学 2025-11-04 Alex Boyd , Andrew Warrington , Taha Kass-Hout , Parminder Bhatia , Danica Xiao

In this paper, we consider a discrete-time stochastic SIR model, where the transmission rate and the true number of infectious individuals are random and unobservable. An advantage of this model is that it permits us to account for random…

物理与社会 · 物理学 2024-01-30 Katia Colaneri , Camilla Damian , Rüdiger Frey

We are interested in estimating the effect of a treatment applied to individuals at multiple sites, where data is stored locally for each site. Due to privacy constraints, individual-level data cannot be shared across sites; the sites may…

机器学习 · 计算机科学 2023-04-04 Ruoxuan Xiong , Allison Koenecke , Michael Powell , Zhu Shen , Joshua T. Vogelstein , Susan Athey

A number of models in mathematical epidemiology have been developed to account for control measures such as vaccination or quarantine. However, COVID-19 has brought unprecedented social distancing measures, with a challenge on how to…

种群与进化 · 定量生物学 2021-09-07 Magdalena Djordjevic , Andjela Rodic , Igor Salom , Dusan Zigic , Ognjen Milicevic , Bojana Ilic , Marko Djordjevic

Infectious diseases are a threat for human health with tremendous impact on our society at large. The recent COVID-19 pandemic, caused by the SARS-CoV-2, is the latest example of a highly infectious disease ravaging the world, since late…

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