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A comprehensive three-dimensional (3D) map of tissue architecture and gene expression is crucial for illuminating the complexity and heterogeneity of tissues across diverse biomedical applications. However, most spatial transcriptomics (ST)…

Volume electron microscopy (vEM) enables nanoscale 3D imaging of biological structures but remains constrained by acquisition trade-offs, leading to anisotropic volumes with limited axial resolution. Existing deep learning methods seek to…

计算机视觉与模式识别 · 计算机科学 2026-03-16 Yumeng He , Zanwei Zhou , Yekun Zheng , Chen Liang , Yunbo Wang , Xiaokang Yang

As Micro-CT technology continues to refine its characterization of material microstructures, industrial CT ultra-precision inspection is generating increasingly large datasets, necessitating solutions to the trade-off between accuracy and…

计算机视觉与模式识别 · 计算机科学 2026-01-22 Yipeng Yin , Rao Yao , Qingying Li , Dazhong Wang , Hong Zhou , Zhijun Fang , Jianing Chen , Longjie Qian , Mingyue Wu

Fast image reconstruction techniques are becoming important with the increasing number of scientific cases in high resolution micro and nano tomography. The processing of the large scale three-dimensional data demands new mathematical tools…

数值分析 · 数学 2016-08-15 Nikolay Koshev , Elias S. Helou , Eduardo X. Miqueles

3D reconstruction is a challenging current topic in medical research. We perform 3D reconstructions from serial sections stained by immunohistological methods. This paper presents an immersive visualisation solution to quality control (QC),…

图形学 · 计算机科学 2021-03-23 Oleg Lobachev , Moritz Berthold , Henriette Pfeffer , Michael Guthe , Birte S. Steiniger

At X-ray beamlines of synchrotron light sources, the achievable time-resolution for 3D tomographic imaging of the interior of an object has been reduced to a fraction of a second, enabling rapidly changing structures to be examined. The…

图像与视频处理 · 电气工程与系统科学 2020-07-06 Marinus J. Lagerwerf , Allard A. Hendriksen , Jan-Willem Buurlage , K. Joost Batenburg

Computed tomography (CT) provides high spatial resolution visualization of 3D structures for scientific and clinical applications. Traditional analytical/iterative CT reconstruction algorithms require hundreds of angular data samplings, a…

图像与视频处理 · 电气工程与系统科学 2024-11-14 Di Xu , Yang Yang , Hengjie Liu , Qihui Lyu , Martina Descovich , Dan Ruan , Ke Sheng

Traffic microsimulation software such as SUMO generate rich spatio-temporal data describing individual vehicle movements, interactions, and support the development of control strategies. While numerical outputs and 2D visualisations are…

图形学 · 计算机科学 2026-04-22 Kevin Riehl , Julius Schlapbach , Anastasios Kouvelas , Michail A. Makridis

Rigorous computer simulations of propagating electromagnetic fields have become an important tool for optical metrology and optics design of nanostructured components. As has been shown in previous benchmarks some of the presently used…

光学 · 物理学 2007-09-25 S. Burger , L. Zschiedrich , F. Schmidt , R. Köhle , T. Henkel , B. Küchler , C. Nölscher

Solar tomography has progressed rapidly in recent years thanks to the development of robust algorithms and the availability of more powerful computers. It can today provide crucial insights in solving issues related to the line-of-sight…

太阳与恒星天体物理 · 物理学 2015-05-27 Nicolas Barbey , Chloé Guennou , Frédéric Auchère

Atomic-resolution imaging with scanning transmission electron microscopy is a powerful tool for characterizing the nanoscale structure of materials, in particular features such as defects, local strains, and symmetry-breaking distortions.…

Segmentation is often an essential intermediate step in image analysis. A volume segmentation characterizes the underlying volume image in terms of geometric information--segments, faces between segments, curves in which several faces…

计算几何 · 计算机科学 2010-10-01 Bjoern Andres , Ullrich Koethe , Thorben Kroeger , Fred A. Hamprecht

Volumetric medical imaging technologies produce detailed 3D representations of anatomical structures. However, effective medical data visualization and exploration pose significant challenges, especially for individuals with limited medical…

人机交互 · 计算机科学 2025-07-01 Qixuan Liu , Shi Qiu , Yinqiao Wang , Xiwen Wu , Kenneth Siu Ho Chok , Chi-Wing Fu , Pheng-Ann Heng

In recent years, machine learning (ML) has gained significant popularity in the field of chemical informatics and electronic structure theory. These techniques often require researchers to engineer abstract "features" that encode chemical…

人机交互 · 计算机科学 2022-07-11 Xiangyun Lei , Fred Hohman , Duen Horng Chau , Andrew J. Medford

Biologists are leading current research on genome characterization (sequencing, alignment, transcription), providing a huge quantity of raw data about many genome organisms. Extracting knowledge from this raw data is an important process…

定量方法 · 定量生物学 2007-05-23 Nicolas Férey , Pierre-Emmanuel Gros , Joan Hérisson , Rachid Gherbi

Particle tracking velocimetry in 3D is becoming an increasingly important imaging tool in the study of fluid dynamics, combustion as well as plasmas. We introduce a dynamic discrete tomography algorithm for reconstructing particle…

流体动力学 · 物理学 2015-01-23 Andreas Alpers , Peter Gritzmann , Dmitry Moseev , Mirko Salewski

Removing noise in computer tomography (CT) data for real-time 3D visualization is vital to improving the quality of the final display. However, the CT noise cannot be removed by straight averaging because the noise has a broadband spatial…

计算机视觉与模式识别 · 计算机科学 2019-09-04 N. Tan Jerome , Z. Ateyev , S. Schmelzle , S. Chilingaryan , A. Kopmann

Realistic microscale domains are an essential step towards making modern multiscale simulations more applicable to computational materials engineering. For this purpose, 3D computed tomography scans can be very expensive or technically…

Electrical impedance tomography is an imaging modality for extracting information on the conductivity distribution inside a physical body from boundary measurements of current and voltage. In many practical applications, it is a priori…

数值分析 · 数学 2014-06-06 Lauri Harhanen , Nuutti Hyvönen , Helle Majander , Stratos Staboulis

An algorithm to efficiently compute the moments of volumetric images is disclosed. The approach demonstrates a reduction in processing time by reducing the computational complexity significantly. Specifically, the algorithm reduces…

计算机视觉与模式识别 · 计算机科学 2020-12-16 William Diggin , Michael Diggin