相关论文: Planning interventions in a controlled pandemic: t…

In light of the continuing emergence of new SARS-CoV-2 variants and vaccines, we create a simulation framework for exploring possible infection trajectories under various scenarios. The situations of primary interest involve the interaction…

The goal of this work is to study the optimal controls for the COVID-19 epidemic in Brazil. We consider an age-structured SEIRQ model with quarantine compartment, where the controls are the quarantine entrance parameters. We then compare…

The COVID-19 pandemic has influenced virtually all aspects of our lives. Across the world, countries have applied various mitigation strategies for the epidemic, based on social, political, and technological instruments. We postulate that…

Testing is a crucial control mechanism for an epidemic outbreak because it enables the health authority to detect and isolate the infected cases, thereby limiting the disease transmission to susceptible people, when no effective treatment…

Contact tracing has been extensively studied from different perspectives in recent years. However, there is no clear indication of why this intervention has proven effective in some epidemics (SARS) and mostly ineffective in some others…

The main focus of this chapter is on public health control strategies which are currently the main way to mitigate COVID-19 pandemic. We introduce and compare compartmental models of increasing complexity for COVID-19 transmission to…

Pandemics can bring a range of devastating consequences to public health and the world economy. Identifying the most effective control strategies has been the imperative task all around the world. Various public health control strategies…

While several non-pharmacological measures have been implemented for a few months in an effort to slow the coronavirus disease (COVID-19) pandemic in the United States, the disease remains a danger in a number of counties as restrictions…

Diverse and complex intervention policies deployed over the last years have shown varied effectiveness in controlling the COVID-19 pandemic. However, a systematic analysis and modelling of the combined effects of different viral lineages…

Epidemics and pandemics have ravaged human life since time. To combat these, novel ideas have always been created and deployed by humanity, with varying degrees of success. At this very moment, the COVID-19 pandemic is the singular global…

In addition to its public health crisis, COVID-19 pandemic has led to the shutdown and closure of workplaces with an estimated total cost of more than $16 trillion. Given the long hours an average person spends in buildings and indoor…

This paper presents a study on a compartmental epidemic model for COVID-19, examining the stability of its equilibrium points upon the introduction of vaccination as a strategy to mitigate the spread of the disease. Initially, the SIQR…

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

Policy responses to COVID-19, particularly those related to non-pharmaceutical interventions, are unprecedented in scale and scope. Epidemiologists are more involved in policy decisions and evidence generation than ever before. However,…

Measures to reduce the impact of the COVID-19 pandemic require a mix of logistic, political and social capacity. Depending on the country, different approaches to increase hospitalization capacity or to properly apply lock-downs are…

The COVID-19 pandemic has resulted in more than 14.5 million infections and 6,04,917 deaths in 212 countries over the last few months. Different drug intervention acting at multiple stages of pathogenesis of COVID-19 can substantially…

In the context of the ongoing Covid-19 pandemic, several reports and studies have attempted to model and predict the spread of the disease. There is also intense debate about policies for limiting the damage, both to health and to the…

This paper studies an optimal control problem for a class of SIR epidemic models, in scenarios in which the infected population is constrained to be lower than a critical threshold imposed by the ICU (intensive care unit) capacity. The…

The COVID-19 pandemic has severely impacted health systems and economies worldwide. Significant global efforts are therefore ongoing to improve vaccine efficacies, optimize vaccine deployment, and develop new antiviral therapies to combat…

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…