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Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics…

统计力学 · 物理学 2023-07-21 Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

The neocortex, a complex system driving multi-region interactions, remains a core puzzle in neuroscience. Despite quantitative insights across brain scales, understanding the mechanisms underlying neural activities is challenging. Advances…

神经元与认知 · 定量生物学 2024-11-27 Xiaochen Wang , Yuxuan Wu , Feng Zhang , Jin Wang

In a first step towards the comprehension of neural activity, one should focus on the stability of the various dynamical states. Even the characterization of idealized regimes, such as a perfectly periodic spiking activity, reveals…

无序系统与神经网络 · 物理学 2014-09-08 Simona Olmi , Antonio Politi , Alessandro Torcini

Models of coupled oscillators are used to describe a wide variety of phenomena in neuroimaging. These models typically rest on the premise that oscillator dynamics do not evolve beyond their respective limit cycles, and hence that…

定量方法 · 定量生物学 2019-09-19 Erik D. Fagerholm , Rosalyn J. Moran , Ines R. Violante , Robert Leech , Karl J. Friston

The models in statistical physics such as an Ising model offer a convenient way to characterize stationary activity of neural populations. Such stationary activity of neurons may be expected for recordings from in vitro slices or…

神经元与认知 · 定量生物学 2017-05-05 Christian Donner , Klaus Obermayer , Hideaki Shimazaki

Phase oscillators are a common starting point for the reduced description of many single neuron models that exhibit a strongly attracting limit cycle. The framework for analysing such models in response to weak perturbations is now…

神经元与认知 · 定量生物学 2013-02-05 Kyle C A Wedgwood , Kevin K Lin , Rüdiger Thul , Stephen Coombes

In this chapter, we utilize dynamical systems to analyze several aspects of machine learning algorithms. As an expository contribution we demonstrate how to re-formulate a wide variety of challenges from deep neural networks, (stochastic)…

动力系统 · 数学 2025-07-08 Dennis Chemnitz , Maximilian Engel , Christian Kuehn , Sara-Viola Kuntz

Whether, when, and how causal interactions between neurons can be meaningfully studied from observations of neural activity alone are vital questions in neural data analysis. Here we aim to better outline the concept of functional…

神经元与认知 · 定量生物学 2023-12-05 Ian H. Stevenson

This paper proposes a class of neural ordinary differential equations parametrized by provably input-to-state stable continuous-time recurrent neural networks. The model dynamics are defined by construction to be input-to-state stable (ISS)…

机器学习 · 计算机科学 2022-02-15 Alan Yang , Jie Xiong , Maxim Raginsky , Elyse Rosenbaum

Demystifying effective connectivity among neuronal populations has become the trend to understand the brain mechanisms of Parkinson's disease, schizophrenia, mild traumatic brain injury, and many other unlisted neurological diseases.…

定量方法 · 定量生物学 2019-09-27 Po-Ya Hsu

We investigate the instabilities and bifurcations of traveling pulses in a model excitable medium; in particular we discuss three different scenarios for the loss of stability resp. the disappearance of stable pulses. In numerical…

斑图形成与孤子 · 物理学 2009-11-07 M. Or-Guil , J. Krishnan , I. G. Kevrekidis , M. Bar

Metastability, characterized by a variability of regimes in time, is a ubiquitous type of neural dynamics. It has been formulated in many different ways in the neuroscience literature, however, which may cause some confusion. In this…

神经元与认知 · 定量生物学 2024-05-24 Kalel L. Rossi , Roberto C. Budzinski , Everton S. Medeiros , Bruno R. R. Boaretto , Lyle Muller , Ulrike Feudel

In exploring the simulation of human rhythmic perception and synchronization capabilities, this study introduces a computational model inspired by the physical and biological processes underlying rhythm processing. Utilizing a reservoir…

神经元与认知 · 定量生物学 2025-03-28 Zhongju Yuan , Wannes Van Ransbeeck , Geraint Wiggins , Dick Botteldooren

Neurodegenerative diseases are characterized by the accumulation of misfolded proteins and widespread disruptions in brain function. Computational modeling has advanced our understanding of these processes, but efforts have traditionally…

We provide a numerical study of the macroscopic model of [3] derived from an agent-based model for a system of particles interacting through a dynamical network of links. Assuming that the network remodelling process is very fast, the…

Empirical estimates of the dimensionality of neural population activity are often much lower than the population size. Similar phenomena are also observed in trained and designed neural network models. These experimental and computational…

神经元与认知 · 定量生物学 2020-02-11 Omri Barak , Sandro Romani

Here we numerically study a model of excitable media, namely, a network with occasionally quiet nodes and connection weights that vary with activity on a short-time scale. Even in the absence of stimuli, this exhibits unstable dynamics,…

无序系统与神经网络 · 物理学 2015-05-19 S. de Franciscis , J. J. Torres , J. Marro

Modeling and parameter estimation for neuronal dynamics are often challenging because many parameters can range over orders of magnitude and are difficult to measure experimentally. Moreover, selecting a suitable model complexity requires a…

动力系统 · 数学 2018-01-31 J. E. Rubin , B. Krauskopf , H. M. Osinga

Traveling waves of neural activity emerge in cortical networks both spontaneously and in response to stimuli. The spatiotemporal structure of waves can indicate the information they encode and the physiological processes that sustain them.…

神经元与认知 · 定量生物学 2023-12-12 Sage Shaw , Zachary P Kilpatrick

The traditional view of neural computation in the cerebral cortex holds that sensory neurons are specialized, i.e., selective for certain dimensions of sensory stimuli. This view was challenged by evidence of contextual interactions between…

神经元与认知 · 定量生物学 2022-04-26 Sergei Gepshtein , Ambarish Pawar , Sunwoo Kwon , Sergey Savel'ev , Thomas D. Albright