相关论文: Time-modulated excitation for enhanced single mole…
The limited bandwidth of optical wireless communication (OWC) front-end devices motivates the use of multiple-input-multiple-output (MIMO) techniques to enhance data rates. It is known that very high multiplexing gains could be achieved by…
Recently, several single-pixel imaging (SPI) schemes have emerged for imaging fast-moving objects and have shown dramatic results. However, fast image reconstruction of a moving object with high quality is still challenging for SPI, thereby…
Photoluminesce (PL) spectroscopy offers excellent methods for mapping the PL decay on the nanosecond time scale. However, capturing maps of emission dynamics on the microsecond time scale can be highly time-consuming. We present a new…
Single molecule fluorescence microscopy is a powerful technique for uncovering detailed information about biological systems, both in vitro and in vivo. In such experiments, the inherently low signal to noise ratios mean that accurate…
Structured illumination microscopy (SIM) is an important super-resolution based microscopy technique that breaks the diffraction limit and enhances optical microscopy systems. With the development of biology and medical engineering, there…
To overcome the physical barriers caused by light diffraction, super-resolution techniques are often applied in fluorescence microscopy. State-of-the-art approaches require specific and often demanding acquisition conditions to achieve…
Our work aims at using quantitative imaging tools to complement the limitation of noise encountered by high resolution fluorescence microscopy methods. Several cycles of fluorophore activation, imaging and deactivation produce a sequence of…
Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…
We present the experimental generation of tunable entanglement between distinct field modes by the delocalized addition of a single photon. We show that one can preserve a high degree of entanglement even between macroscopically populated…
We describe a fast closed-loop optimization wavefront shaping system able to focus light through dynamic scattering media. A MEMS-based spatial light modulator (SLM), a fast photodetector and FPGA electronics are combined to implement a…
Optical super-resolution microscopy is a key technology for structural biology that offers high imaging contrast and live-cell compatibility. Minimal (fluorescence) photons flux microscopy, or MINFLUX, is an emerging super-resolution…
Super-resolution microscopy has revolutionized the imaging of complex physical and biological systems by surpassing the Abbe diffraction limit. Recent advancements, particularly in single-molecule localization microscopy (SMLM), have pushed…
Super-resolution imaging based on single molecule localization allows accessing nanometric-scale information in biological samples with high precision. However, complete measurements including molecule orientation are still challenging.…
Spatial Modulation (SM) is a technique that can enhance the capacity of MIMO schemes by exploiting the index of transmit antenna to convey information bits. In this paper, we describe this technique, and present a new MIMO transmission…
Structured Illumination Microscopy (SIM) allows access to spatial information beyond the diffraction limit by folding high frequency components into the optical system's base-band. Using various algorithmic techniques, an image containing…
Spatiotemporal mode-locking (STML) has become an emerging approach to realize organized wavepackets in high-dimensional nonlinear photonic systems. Mode-locking in one dimensional systems employs a saturable absorber to resist fluctuations…
Modulation-enhanced localization microscopy (MELM) has demonstrated significant improvements in both lateral and axial localization precision compared to conventional single-molecule localization microscopy (SMLM). However, lateral…
Colocalization analysis aims to study complex spatial associations between bio-molecules via optical imaging techniques. However, existing colocalization analysis workflows only assess an average degree of colocalization within a certain…
Single molecule localization microscopy is widely used in biological research for measuring the nanostructures of samples smaller than the diffraction limit. This study uses multifocal plane microscopy and addresses the 3D single molecule…
SPAD cameras offer single photon detection sensitivity, high frame rates and zero readout noise. They are a core technology for widefield FLIM, but have further potential in ultra-fast imaging applications. However, in practice sensitivity…