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Understanding complex biological macromolecules, especially proteins, is vital for grasping their diverse chemical functions with direct impact in biology and pharmacology. While techniques like X-ray crystallography and cryo-electron…

生物大分子 · 定量生物学 2024-04-12 S. H. Mejias , A. L. Cortajarena , R. Mincigrucci , C. Svetina , C. Masciovecchio

X-ray free-electron lasers (XFELs) have been widely used for applications such as X-ray crystallography and magnetic spin probes because of their unprecedented performance. Recently, time-resolved X-ray magnetic circular dichroism (XMCD)…

仪器与探测器 · 物理学 2018-07-04 Bangjie Deng , Jiawei Yan , Qingmin Zhang , Yaodong Sang , Haixiao Deng

Serial femtosecond X-ray crystallography (SFX) captures the structure and dynamics of biological macromolecules at high spatial and temporal resolutions. The ultrashort pulse produced by an X-ray free electron laser (XFEL) 'outruns' much of…

等离子体物理 · 物理学 2025-06-03 Spencer K. Passmore , Alaric L. Sanders , Andrew V. Martin , Harry M. Quiney

A deep understanding of molecular photo-transformations is challenging because of the complex interaction between the configurations of electrons and nuclei. An initial optical excitation dissipates energy into electronic and structural…

The advent of X-ray free-electron lasers (XFELs) has revolutionized fundamental science, from atomic to condensed matter physics, from chemistry to biology, giving researchers access to X-rays with unprecedented brightness, coherence, and…

介观与纳米尺度物理 · 物理学 2022-10-27 Nanna Zhou Hagström , Michael Schneider , Nico Kerber , Alexander Yaroslavtsev , Erick Burgos Parra , Marijan Beg , Martin Lang , Christian M. Günther , Boris Seng , Fabian Kammerbauer , Horia Popescu , Matteo Pancaldi , Kumar Neeraj , Debanjan Polley , Rahul Jangid , Stjepan B. Hrkac , Sheena K. K. Patel , Sergei Ovcharenko , Diego Turenne , Dmitriy Ksenzov , Christine Boeglin , Igor Pronin , Marina Baidakova , Clemens von Korff Schmising , Martin Borchert , Boris Vodungbo , Kai Chen , Chen Luo , Florin Radu , Leonard Müller , Miriam Martínez Flórez , André Philippi-Kobs , Matthias Riepp , Wojciech Roseker , Gerhard Grübel , Robert Carley , Justine Schlappa , Benjamin Van Kuiken , Rafael Gort , Laurent Mercadier , Naman Agarwal , Loïc Le Guyader , Giuseppe Mercurio , Martin Teichmann , Jan Torben Delitz , Alexander Reich , Carsten Broers , David Hickin , Carsten Deiter , James Moore , Dimitrios Rompotis , Jinxiong Wang , Daniel Kane , Sandhya Venkatesan , Joachim Meier , Florent Pallas , Tomasz Jezynski , Maximilian Lederer , Djelloul Boukhelef , Janusz Szuba , Krzysztof Wrona , Steffen Hauf , Jun Zhu , Martin Bergemann , Ebad Kamil , Thomas Kluyver , Robert Rosca , Michał Spirzewski , Markus Kuster , Monica Turcato , David Lomidze , Andrey Samartsev , Jan Engelke , Matteo Porro , Stefano Maffessanti , Karsten Hansen , Florian Erdinger , Peter Fischer , Carlo Fiorini , Andrea Castoldi , Massimo Manghisoni , Cornelia Beatrix Wunderer , Eric E. Fullerton , Oleg G. Shpyrko , Christian Gutt , Cecilia Sanchez-Hanke , Hermann A. Dürr , Ezio Iacocca , Hans T. Nembach , Mark W. Keller , Justin M. Shaw , Thomas J. Silva , Roopali Kukreja , Hans Fangohr , Stefan Eisebitt , Mathias Kläui , Nicolas Jaouen , Andreas Scherz , Stefano Bonetti , Emmanuelle Jal

We demonstrate the potential of X-ray free-electron lasers (XFEL) to advancethe understanding of complex plasma dynamics by allowing for the first time nanometer and femtosecond resolution at the same time in plasma diagnostics. Plasma…

X-ray Free Electron Lasers (XFEL) are revolutionary photons sources, whose ultrashort, brilliant pulses are expected to allow single molecule diffraction experiments providing structural information on the atomic length scale. This ultimate…

光学 · 物理学 2015-05-20 Andrea Fratalocchi , Giancarlo Ruocco

X-ray free electron laser (XFEL) experiments have brought unique capabilities and opened new directions in research, such as creating new states of matter or directly measuring atomic motion. One such area is the ability to use finely…

High-brightness femtosecond-to-attosecond pulses are indispensable for probing electron dynamics on their fundamental temporal scales. X-ray free-electron lasers (XFELs) at high repetition rates will facilitate high-statistics measurements…

加速器物理 · 物理学 2026-05-01 Junhao Liu , Zhen Wang , Lanpeng Ni , Yujie Lu , Chao Feng , Zhentang Zhao

The routine atomic-resolution structure determination of single particles is expected to have profound implications for probing the structure-function relationship in systems ranging from energy materials to biological molecules.…

Single biomolecular imaging using XFEL radiation is an emerging method for protein structure determination using the "diffraction before destruction" method at near atomic resolution. Crucial parameters for such bio-imaging experiments are…

We demonstrate X-ray phase contrast microscopy performed at the European X-ray Free-Electron Laser sampled at 1.128 MHz rate. We have applied this method to image stochastic processes induced by an optical laser incident on water-filled…

X-ray free electron lasers (XFEL) create femtosecond X-ray pulses with high brightness and high longitudinal coherence allowing to extend X-ray spectroscopy and scattering techniques into the ultrafast time-domain. These X-rays are a…

The European X-ray Free Electron Laser (XFEL) will deliver 27000 fully coherent, high brilliance X-ray pulses per second each with a duration below 100 fs. This will allow the recording of diffraction patterns of single molecules and the…

仪器与探测器 · 物理学 2015-06-03 J. Schwandt , E. Fretwurst , R. Klanner , I. Pintilie , J. Zhang

X-ray free electron laser (XFEL) can provide X-ray light with about four order of magnitude higher flux than synchrotron radiation. Pulse light from XFEL interacts with the target and the resulting photons are collected by detectors. The…

仪器与探测器 · 物理学 2021-10-13 Shuo Zhang , Jing-Kai Xia , Xu-Dong Ju

The advent of isolated and intense sub-femtosecond X-ray pulses enables tracking of quantummechanical motion of electrons in molecules and solids. The combination of X-ray spectroscopy and diffraction imaging is a powerful approach to…

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