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In this paper we explore avenues for improving the reliability of dimensionality reduction methods such as Non-Negative Matrix Factorization (NMF) as interpretive exploratory data analysis tools. We first explore the difficulties of the…

人工智能 · 计算机科学 2009-04-22 Nikolaos Vasiloglou , Alexander G. Gray , David V. Anderson

Neuro-encoded expression programming(NEEP) that aims to offer a novel continuous representation of combinatorial encoding for genetic programming methods is proposed in this paper. Genetic programming with linear representation uses…

神经与进化计算 · 计算机科学 2021-04-12 Aftab Anjum , Fengyang Sun , Lin Wang , Jeff Orchard

Emerging integrative analysis of genomic and anatomical imaging data which has not been well developed, provides invaluable information for the holistic discovery of the genomic structure of disease and has the potential to open a new…

基因组学 · 定量生物学 2014-09-16 Junhai Jiang , Nan Lin , Shicheng Guo , Jinyun Chen , Momiao Xiong

Motivation: Modelling methods that find structure in data are necessary with the current large volumes of genomic data, and there have been various efforts to find subsets of genes exhibiting consistent patterns over subsets of treatments.…

机器学习 · 计算机科学 2016-09-15 Kerstin Bunte , Eemeli Leppäaho , Inka Saarinen , Samuel Kaski

Mesh-based simulations play a key role when modeling complex physical systems that, in many disciplines across science and engineering, require the solution of parametrized time-dependent nonlinear partial differential equations (PDEs). In…

数值分析 · 数学 2023-08-04 Nicola Rares Franco , Stefania Fresca , Filippo Tombari , Andrea Manzoni

Nuclear Magnetic Resonance (NMR) spectra are widely used in metabolomics to obtain profiles of metabolites dissolved in biofluids such as cell supernatants. Methods for estimating metabolite concentrations from these spectra are presently…

统计方法学 · 统计学 2012-05-16 William Astle , Maria De Iorio , Sylvia Richardson , David Stephens , Timothy Ebbels

The nonnegative matrix factorization (NMF) is widely used in signal and image processing, including bio-informatics, blind source separation and hyperspectral image analysis in remote sensing. A great challenge arises when dealing with a…

计算机视觉与模式识别 · 计算机科学 2016-03-29 Fei Zhu , Paul Honeine , Maya Kallas

Discovery of diagnostic and prognostic molecular markers is important and actively pursued the research field in cancer research. For complex diseases, this process is often performed using Machine Learning. The current study compares two…

基因组学 · 定量生物学 2020-04-30 Aneta Polewko-Klim , Witold R. Rudnicki

Imbalanced classification presents a formidable challenge in machine learning, particularly when tabular datasets are plagued by noise and overlapping class boundaries. From a geometric perspective, the core difficulty lies in the…

机器学习 · 计算机科学 2026-02-16 Xubin Wang , Qing Li , Weijia Jia

Graph Neural Networks (GNN) exhibit superior performance in graph representation learning, but their inference cost can be high, due to an aggregation operation that can require a memory fetch for a very large number of nodes. This…

机器学习 · 计算机科学 2025-03-18 Yaochen Hu , Mai Zeng , Ge Zhang , Pavel Rumiantsev , Liheng Ma , Yingxue Zhang , Mark Coates

A recent theoretical analysis shows the equivalence between non-negative matrix factorization (NMF) and spectral clustering based approach to subspace clustering. As NMF and many of its variants are essentially linear, we introduce a…

机器学习 · 统计学 2018-10-08 Dijana Tolic , Nino Antulov-Fantulin , Ivica Kopriva

We propose Geometric Neural Parametric Models (GNPM), a learned parametric model that takes into account the local structure of data to learn disentangled shape and pose latent spaces of 4D dynamics, using a geometric-aware architecture on…

计算机视觉与模式识别 · 计算机科学 2022-09-23 Mirgahney Mohamed , Lourdes Agapito

Traditional nonnegative matrix factorization (NMF) learns a new feature representation on the whole data space, which means treating all features equally. However, a subspace is often sufficient for accurate representation in practical…

计算机视觉与模式识别 · 计算机科学 2022-04-19 Junhang Li , Jiao Wei , Can Tong , Tingting Shen , Yuchen Liu , Chen Li , Shouliang Qi , Yudong Yao , Yueyang Teng

Recent advances in Spatial Transcriptomics (ST) pair histology images with spatially resolved gene expression profiles, enabling predictions of gene expression across different tissue locations based on image patches. This opens up new…

计算机视觉与模式识别 · 计算机科学 2025-03-21 Aniruddha Ganguly , Debolina Chatterjee , Wentao Huang , Jie Zhang , Alisa Yurovsky , Travis Steele Johnson , Chao Chen

With the proliferation of Graph Neural Network (GNN) methods stemming from contrastive learning, unsupervised node representation learning for graph data is rapidly gaining traction across various fields, from biology to molecular dynamics,…

机器学习 · 计算机科学 2024-08-01 Jihee You , So Won Jeong , Claire Donnat

Nonsmooth Nonnegative Matrix Factorization (nsNMF) is capable of producing more localized, less overlapped feature representations than other variants of NMF while keeping satisfactory fit to data. However, nsNMF as well as other existing…

计算机视觉与模式识别 · 计算机科学 2018-03-21 Jinshi Yu , Guoxu Zhou , Andrzej Cichocki , Shengli Xie

Mixed pixels are presented in hyperspectral images due to low spatial resolution of hyperspectral sensors. Spectral unmixing decomposes mixed pixels spectra into endmembers spectra and abundance fractions. In this paper using of robust…

计算机视觉与模式识别 · 计算机科学 2012-12-06 Roozbeh Rajabi , Hassan Ghassemian

Traditional methods for high-dimensional diffeomorphic mapping often struggle with the curse of dimensionality. We propose a mesh-free learning framework designed for $n$-dimensional mapping problems, seamlessly combining variational…

机器学习 · 计算机科学 2025-11-05 Zhiwen Li , Cheuk Hin Ho , Lok Ming Lui

Nonnegative matrix factorization (NMF) is widely used for clustering with strong interpretability. Among general NMF problems, symmetric NMF is a special one that plays an important role in graph clustering where each element measures the…

机器学习 · 计算机科学 2023-11-07 Mengyuan Zhang , Kai Liu

Accurately simulating soft tissue deformation is crucial for surgical training, pre-operative planning, and real-time haptic feedback systems. While physics-based models such as the finite element method (FEM) provide high-fidelity results,…

图像与视频处理 · 电气工程与系统科学 2025-09-23 Madina Kojanazarova , Sidaty El Hadramy , Jack Wilkie , Georg Rauter , Philippe C. Cattin