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Dynamic models are widely used to mathematically describe biological phenomena that evolve over time. One important area of application is leukaemia research, where leukaemia cells are genetically modified in preclinical studies to explore…

统计方法学 · 统计学 2026-02-02 Julian Wäsche , Romina Ludwig , Irmela Jeremias , Christiane Fuchs

Deep generative models produce data according to a learned representation, e.g. diffusion models, through a process of approximation computing possible samples. Approximation can be understood as reconstruction and the large datasets used…

人机交互 · 计算机科学 2023-09-25 Luís Arandas , Mick Grierson , Miguel Carvalhais

Epigenetic Tracking is a mathematical model of biological cells, originally conceived to study embryonic development. Computer simulations proved the capacity of the model to generate complex 3-dimensional cellular structures, and the…

细胞行为 · 定量生物学 2015-07-07 Alessandro Fontana

We introduce a broad class of spatial models to describe how spatially heterogeneous populations live, die, and reproduce. Individuals are represented by points of a point measure, whose birth and death rates can depend both on spatial…

Predictive modeling of the evolutionary dynamics of cancer is a challenge issue in computational cancer biology. In this paper, we propose a general mathematical model framework for the evolutionary dynamics of cancer with plasticity and…

细胞行为 · 定量生物学 2020-01-10 Jinzhi Lei

In this work we review some recent development in the mathematical modelling of quantitative sociology by means of statistical mechanics. After a short pedagogical introduction to static and dynamic properties of many body systems, we…

物理与社会 · 物理学 2009-10-15 Elena Agliari , Adriano Barra , Raffaella Burioni , Pierluigi Contucci

Some populations, such as red blood cells (RBCs), exhibit a pattern of population decline that is closer to linear rather than exponential, which has proven to be unexpectedly challenging to describe with a single simple mathematical model.…

种群与进化 · 定量生物学 2020-04-14 Irina Kareva , Georgy Karev

Stochastic dynamics govern many important processes in cellular biology, and an underlying theoretical approach describing these dynamics is desirable to address a wealth of questions in biology and medicine. Mathematical tools exist for…

定量方法 · 定量生物学 2016-02-17 Iain G. Johnston , Nick S. Jones

In this study, based on our previous study, we examined the mathematical properties, especially the stability of the equilibrium for our proposed mathematical model. By means of the results of the stability in this study, we also used…

计算机与社会 · 计算机科学 2019-09-04 Yasushi Ota , Naoki Mizutani

In many indigenous societies, people are categorised into several cultural groups, or clans, within which they believe to share ancestors. Clan attributions provide certain rules for marriage and descent. Such rules between clans constitute…

物理与社会 · 物理学 2021-12-07 Kenji Itao , Kunihiko kaneko

In this article, we consider time-changed models of population evolution $\mathcal{X}^f(t)=\mathcal{X}(H^f(t))$, where $\mathcal{X}$ is a counting process and $H^f$ is a subordinator with Laplace exponent $f$. In the case $\mathcal{X}$ is a…

概率论 · 数学 2015-04-02 Enzo Orsingher , Costantino Ricciuti , Bruno Toaldo

We present numerical results based on a simplified ecological system in evolution, showing features of extinction similar to that claimed for the biosystem on Earth. In the model each species consists of a population in interaction with the…

adap-org · 物理学 2009-10-28 Guillermo Abramson

We consider populations structured by a phenotypic trait and a space variable, in a non-homogeneous environment. In the case of sex- ual populations, we are able to derive models close to existing mod- els in theoretical biology, from a…

偏微分方程分析 · 数学 2011-05-11 Sepideh Mirrahimi , Gael Raoul

The idea is advanced that strong perturbations of an initially equilibrium Bose-condensed gas lead to the sequence of nonequilibrium states whose order is inverse to the sequence of states arising in the process of the Bose-gas relaxation…

量子气体 · 物理学 2015-02-24 V. I. Yukalov , E. P. Yukalova

Why are human societies unstable? Theories based on the observation of recurring patterns in historical data indicate that economic inequality, as well as social factors are key drivers. So far, models of this phenomenon are more…

物理与社会 · 物理学 2025-06-24 Alexander Jochim , Stefan Bornholdt

We analyze a mathematical model to understand the dynamics of bullying in schools. The model considers a population divided into four groups: susceptible individuals, bullies, individuals exposed to bullying, and violent individuals.…

物理与社会 · 物理学 2025-01-10 Nuno Crokidakis

Augmenting classical epidemiological models with information from the social sciences helps unveil the interplay between contagion dynamics and social responses. However, multidisciplinary integration of social analysis and epidemiological…

物理与社会 · 物理学 2025-07-29 Daniele Proverbio , Riccardo Tessarin , Giulia Giordano

The connection between contradictory public opinions, heterogeneous believes and the emergence of democratic or dictatorial extremism is studied extending our former two state dynamic opinion model. Agents are attached to a social-cultural…

其他凝聚态物理 · 物理学 2009-11-10 Serge Galam

We study a stochastic model of urban growth generating spatial distributions of population densities at an intermediate mesoscopic scale. The model is based on the antagonist interplay between the two opposite abstract processes of…

物理与社会 · 物理学 2018-11-21 Juste Raimbault

This essay provides a critical overview of the mathematical kinetic theory of active particles, which is used to model and study collective systems consisting of interacting living entities, such as those involved in behavior and evolution.…

物理与社会 · 物理学 2025-10-17 Marina Dolfin , Leone Leonida