相关论文: Chromatic Confocal Tomography
A promising way to measure the distribution of matter on small scales (k ~ 10 hMpc^-1) is to use gravitational lensing of the Cosmic Microwave Background (CMB). CMB-HD, a proposed high-resolution, low-noise millimeter survey over half the…
We experimentally demonstrate an all-fiber spectrometer consisting of a photonic bandgap fiber bundle and a black and white CCD camera. Photonic crystal fibers used in this work are the large solid core all-plastic Bragg fibers designed for…
Scanning fluorescence correlation spectroscopy (SFCS) with a scan path perpendicular to the membrane plane was introduced to measure diffusion and interactions of fluorescent components in free standing biomembranes. Using a confocal laser…
We have designed, fabricated and tested a lens with chromatic aberration coefficient (Cc) of 1.0 mm, a 4.0 mm pole-gap and 2.0 mm bore that is wide enough to accommodate an anti-contamination system and an objective aperture. This lens…
Multispectral imaging plays an important role in many applications from astronomical imaging, earth observation to biomedical imaging. However, the current technologies are complex with multiple alignment-sensitive components, predetermined…
Contrastive learning (CL) has become a powerful approach for learning representations from unlabeled images. However, existing CL methods focus predominantly on visual appearance features while neglecting topological characteristics (e.g.,…
We demonstrate an electro-optic wide-field method to enable fluorescence lifetime microscopy (FLIM) with high throughput and single-molecule sensitivity. Resonantly driven Pockels cells are used to efficiently gate images at 39 MHz,…
The outbreak of COVID-19 exposed the inadequacy of our technical tools for home health surveillance, and recent studies have shown the potential of smartphones as a universal optical microscopic imaging platform for such applications.…
A fluorescence correlation spectroscopy (FCS) system based on two independent measurement volumes is presented. The optical setup and data acquisition hardware are detailed, as well as a complete protocol to control the location, size and…
The Fresnel Interferometric Imager is a space-based astronomical telescope project yielding milli-arc second angular resolution and high contrast images with loose manufacturing constraints. This optical concept involves diffractive…
Using photonic devices, we developed a new approach to traditional spectroscopy where the spectral cross-correlation with a template spectrum can be done entirely on-device. By creating photonic devices with a carefully designed, modulated…
We fabricate two kinds of 100% fill factor compound eye structures using direct laser writing, including conventional compound eyes (CVCEs) with the same focal length of each microlens unit, and specially designed confocal compound eyes…
Defocused speckle photography has long been used to measure rotations of rough surfaces. This paper explains how, by adding a suitably perforated mask, some measurement properties, such as range or lateral resolution, may be changed at…
The significant optical and size benefits of using a curved focal surface for imaging systems have been well studied yet never brought to market for lack of a high-quality, mass-producible, curved image sensor. In this work we demonstrate…
High-contrast imaging provided by a coronagraph is critical for the direction imaging of the Earth-like planet orbiting its bright parent star. A major limitation for such direct imaging is the speckle noise that is induced from the…
An ongoing limitation of terahertz spectroscopy is that the technique is generally limited to the study of relatively large samples of order 4 mm across due to the generally large size of the focal beam spot. We present a nested concentric…
The main advantage of two-photon fluorescence confocal microscopy is the low absorption obtained with live tissues at the wavelengths of operation. However, the resolution of two-photon fluorescence confocal microscopes is lower than in the…
Reflectance confocal microscopy (RCM) is an effective, non-invasive pre-screening tool for skin cancer diagnosis, but it requires extensive training and experience to assess accurately. There are few quantitative tools available to…
Biophotonics is an active research area in molecular imaging, genetic diagnosis and prognosis, with direct applicability in precision medicine. However, long-standing challenges of biophotonics are well known due to low signal-to-noise…
This article experimentally examines different configurations of a novel multi-camera array microscope (MCAM) imaging technology. The MCAM is based upon a densely packed array of "micro-cameras" to jointly image across a large field-of-view…