相关论文: A Model-Based Architecture for Automatic Anesthesi…
Intensive care unit (ICU) patients exhibit erratic blood glucose (BG) fluctuations, including hypoglycemic and hyperglycemic episodes, and require exogenous insulin delivery to keep their BG in healthy ranges. Glycemic control via glycemic…
In-bed human mesh recovery can be crucial and enabling for several healthcare applications, including sleep pattern monitoring, rehabilitation support, and pressure ulcer prevention. However, it is difficult to collect large real-world…
In drug-resistant epilepsy, presurgical evaluation of epilepsy can be considered. Magnetoencephalography (MEG) has been shown to be an effective exam to inform the localization of the epileptogenic zone through the localization of…
Smart Infusion Pumps are vital tools for use in administering a broad range of parenteral/intravenous medications. Safe and effective use of smart infusion pumps depends upon their integration with Pump Servers, Computerized Physician Order…
Model predictive control (MPC) has proven useful in enabling safe and optimal motion planning for autonomous vehicles. In this paper, we investigate how to achieve MPC-based motion planning when a neural state-space model represents the…
Purpose: Pencil beam scanning proton therapy is sensitive to respiratory motion, leading to potential dose inhomogeneities due to interplay effects. We developed and validated a predictive framework to assess interplay and motion robustness…
A new agent architecture called Limited Instruction Set Agent (LISA) is introduced for autonomous control. The new architecture is based on previous implementations of AgentSpeak and it is structurally simpler than its predecessors with the…
Sepsis is a leading cause of mortality in intensive care units (ICUs) and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and…
Inspire therapy is an FDA-approved internal neurostimulation treatment for obstructive sleep apnea. However, not all patients respond to this therapy, posing a challenge even for experienced otolaryngologists to determine candidacy. This…
As an effective method to deliver external materials into biological cells, microinjection has been widely applied in the biomedical field. However, the cognition of cell mechanical property is still inadequate, which greatly limits the…
Control of an inflammatory immune response is still an ongoing research. Here, a strategy consisting of manipulating a pro and anti-inflammatory mediator is considered. Already existing and promising model-based techniques suffer…
Actuating the acoustic resonance modes of a microfluidic device containing suspended particles (e.g., cells) allows for the manipulation of their individual positions. In this work, we investigate how the number of resonance modes $M$…
We present a problem-suited numerical method for a particularly challenging cancer invasion model. This model is a multiscale haptotaxis advection-reaction-diffusion system that describes the macroscopic dynamics of two types of cancer…
Model predictive control (MPC) is an optimal control strategy where control input calculation is based on minimizing the predicted tracking error over a finite horizon that moves with time. This strategy has an advantage over conventional…
Model predictive control (MPC) is a de facto standard control algorithm across the process industries. There remain, however, applications where MPC is impractical because an optimization problem is solved at each time step. We present a…
This paper presents a novel mechatronic setup intended for providing respiratory support to patients suffering from pulmonary failure. The setup relies upon the circulation of an oxygenated perfluorocarbon (PFC) through the abdominal…
Cyber-physical systems (CPSs) are now widely deployed in many industrial domains, e.g., manufacturing systems and autonomous vehicles. To further enhance the capability and applicability of CPSs, there comes a recent trend from both…
The process of programmed cell death, namely apoptosis, is a natural mechanism that regulates healthy tissue, multicellular structures, and homeostasis. An improved understanding of apoptosis can significantly enhance our knowledge of…
The Auto-ICell system, a novel, and cost-effective integrated droplet microfluidic system, is introduced for real-time analysis of single-cell morphology and apoptosis. This system integrates a 3D-printed microfluidic chip with image…
Epilepsy can be treated with medication, however, $30\%$ of epileptic patients are still drug resistive. Devices like responsive neurostimluation systems are implanted in select patients who may not be amenable to surgical resection.…