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Finite Element Modeling (FEM) has been widely used to model the electric field distribution, to study the interaction between stimulation electrodes and neural tissue. However, due to the insufficient computational capability to represent…

神经元与认知 · 定量生物学 2019-08-22 Jiahui Wang , Hao Wanga , Xin Yuan Thow , Nitish V. Thakor

Objective: Closed-loop deep brain stimulation (DBS) may improve current clinical DBS treatment for neurological movement disorders, but control algorithms may perform differently across patients. New metrics are needed for comparing and…

神经元与认知 · 定量生物学 2016-05-31 Jeffrey Herron , Anca Velisar , Mahsa Malekmohammadi , Helen Bronte-Stewart , Howard Jay Chizeck

The human neuromuscular system consisting of skeletal muscles and neural circuits is a complex system that is not yet fully understood. Surface electromyography (EMG) can be used to study muscle behavior from the outside. Computer…

分布式、并行与集群计算 · 计算机科学 2021-07-16 Benjamin Maier

Neurotechnologies are transforming how we measure, interpret, and modulate brain-body interactions, integrating real-time sensing, computation, and stimulation to enable precise physiological control. They hold transformative potential…

Mental disorders (MD) are among the top most demanding challenges in world-wide health. According to the World Health Organization, the burden of MDs continues to grow with significant impact on health and major social and human rights. A…

神经元与认知 · 定量生物学 2023-03-21 Thomas Wahl , Joséphine Riedinger , Michel Duprez , Axel Hutt

At-home rehabilitation for post-stroke patients presents significant challenges, as continuous, personalized care is often limited outside clinical settings. Moreover, the lack of integrated solutions capable of simultaneously monitoring…

Neuromodulation techniques have emerged as promising approaches for treating a wide range of neurological disorders, precisely delivering electrical stimulation to modulate abnormal neuronal activity. While leveraging the unique…

Background. Bimanual psychomotor proficiency is fundamental to neurosurgical procedures, yet it remains difficult for trainees to acquire and for educators to objectively evaluate performance. In this study, we investigate the feasibility…

A new hybrid tracking controller for neuromuscular electrical stimulation is proposed. The control scheme uses sampled measurements and is designed by utilizing a numerical prediction of the state variables. The tracking error of the…

最优化与控制 · 数学 2013-10-08 Iasson Karafyllis , Michael Malisoff , Marcio de Queiroz , Miroslav Krstic

Adaptive deep brain stimulation (aDBS) has emerged as a promising treatment for Parkinson disease (PD). In aDBS, a surgically placed electrode sends dynamically altered stimuli to the brain based on neurophysiological feedback: an invasive…

神经元与认知 · 定量生物学 2025-05-16 Ekaterina Kuzmina , Dmitrii Kriukov , Mikhail Lebedev , Dmitry V. Dylov

In this paper we present an efficient model of the neuronal potentials recorded by a deep brain stimulation microelectrode (DBS MER) in the subthalamic nucleus. It is shown that a computationally efficient filtered point process consisting…

神经元与认知 · 定量生物学 2016-07-05 Kristian J. Weegink , Paul A. Bellette , John J. Varghese , Peter A. Silburn , Paul A. Meehan , Andrew P. Bradley

Energy efficiency and low latency are crucial requirements for designing wearable AI-empowered human activity recognition systems, due to the hard constraints of battery operations and closed-loop feedback. While neural network models have…

神经与进化计算 · 计算机科学 2023-08-03 Sizhen Bian , Michele Magno

Transcranial ultrasonic stimulation (TUS) is rapidly gaining traction for non-invasive human neuromodulation, with a pressing need to establish protocols that maximise neuromodulatory efficacy. In this review, we aggregate and examine…

生物物理 · 物理学 2024-07-04 Tulika Nandi , Benjamin R. Kop , Kim Butts Pauly , Charlotte J. Stagg , Lennart Verhagen

Neuropathies are gaining higher relevance in clinical settings, as they risk permanently jeopardizing a person's life. To support the recovery of patients, the use of fully implanted devices is emerging as one of the most promising…

人工智能 · 计算机科学 2024-04-03 Antonio Coviello , Francesco Linsalata , Umberto Spagnolini , Maurizio Magarini

Deep brain stimulation (DBS) has the potential to improve the quality of life of people with a variety of neurological diseases. A key challenge in DBS is in the placement of a stimulation electrode in the anatomical location that maximizes…

This paper presents a multi-stage experimental framework that integrates immersive Virtual Reality (VR) simulations, wearable sensors, and advanced signal processing to investigate construction workers neuro-physiological stress responses…

人机交互 · 计算机科学 2025-10-07 Fatemeh Banani Ardecani , Omidreza Shoghli

Mental disorders may exhibit pathological brain rhythms and neurostimulation promises to alleviate of patients' symptoms by modifying these rhythms. Today, most neurostimulation schemes are open-loop, i.e. administer experimental…

神经元与认知 · 定量生物学 2023-03-21 Thomas Wahl , Michel Duprez , Axel Hutt

Neuromorphic computing systems are embracing memristors to implement high density and low power synaptic storage as crossbar arrays in hardware. These systems are energy efficient in executing Spiking Neural Networks (SNNs). We observe that…

神经与进化计算 · 计算机科学 2021-03-11 Twisha Titirsha , Shihao Song , Anup Das , Jeffrey Krichmar , Nikil Dutt , Nagarajan Kandasamy , Francky Catthoor

A deep neural network (DNN) that can reliably model muscle responses from corresponding brain stimulation has the potential to increase knowledge of coordinated motor control for numerous basic science and applied use cases. Such cases…

The modeling and simulation of coupled neuromusculoskeletal-exoskeletal systems play a crucial role in human biomechanical analysis, as well as in the design and control of exoskeletons. However, conventional dynamic simulation frameworks…

机器人学 · 计算机科学 2023-11-07 Wei Jin , Jiaqi Liu , Qiwei Zhang , Xiaoxu Zhang , Qining Wang , Hongbin Fang , Jian Xu
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