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Speckle noise and retinal shadows within OCT B-scans occlude important edges, fine textures and deep tissues, preventing accurate and robust diagnosis by algorithms and clinicians. We developed a single process that successfully removed…

Purpose: Recently the authors presented a technique that allows corneal thickness measurements along any meridian from optical sections obtained using a rotary scanning system. This paper presents 3-D mapping of the corneal thickness and…

综合物理 · 物理学 2007-05-23 S. Franco , J. B. Almeida , M. Parafita

Dispersion is a common phenomenon in optics due to the frequency dependence of the refractive index in polychromatic light. This issue, if left untreated in optical coherence tomography (OCT) imaging, leads to signal broadening of the…

图像与视频处理 · 电气工程与系统科学 2022-01-03 Shangbang Luo , Guy Holland , Eric Mikula , Samantha Bradford , Reza Khazaeinezhad , James V Jester , Tibor Juhasz

Optical coherence tomography (OCT) is a non-invasive imaging technique with extensive clinical applications in ophthalmology. OCT enables the visualization of the retinal layers, playing a vital role in the early detection and monitoring of…

Background: Changes in choroidal thickness are associated with various ocular diseases and the choroid can be imaged using spectral-domain optical coherence tomography (SDOCT) and enhanced depth imaging OCT (EDIOCT). New Method: Eighty…

This paper presents a novel automated system that segments six sub-retinal layers from optical coherence tomography (OCT) image stacks of healthy patients and patients with diabetic macular edema (DME). First, each image in the OCT stack is…

计算机视觉与模式识别 · 计算机科学 2016-10-25 Sohini Roychowdhury , Dara D. Koozekanani , Michael Reinsbach , Keshab K. Parhi

Purpose. This study was conducted to determine the thickness map of eleven retinal layers in normal subjects by spectral domain optical coherence tomography (SD-OCT) and evaluate their association with sex and age. Methods. Mean regional…

计算机视觉与模式识别 · 计算机科学 2013-12-12 Raheleh Kafieh , Hossein Rabbani , Fedra Hajizadeh , Michael D. Abramoff , Milan Sonka

Corneal evaluation in ophthalmology necessitates cellular-resolution and fast imaging techniques allowing accurate diagnoses. Currently, the fastest volumetric imaging technique is Fourier-domain full-field optical coherence tomography…

Corneal collagen crosslinking (CXL) is commonly used to prevent or treat keratoconus. Although changes in corneal stiffness induced by CXL surgery can be monitored with non-contact dynamic optical coherence elastography (OCE) by tracking…

Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…

图像与视频处理 · 电气工程与系统科学 2022-10-26 Botond Fazekas , Guilherme Aresta , Dmitrii Lachinov , Sophie Riedl , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

PURPOSE: Establishing and obtaining consistent quantitative indices of retinal thickness from a variety of clinically used Spectral-Domain Optical Coherence Tomography scanners. DESIGN: Retinal images from five Spectral-Domain Optical…

Optical sections of the cornea are obtained by illumination with a collimated beam expanded in a fan shape by a small rotary cylindrical lens. The light diffused from the cornea is observed by two cameras and processed in order to yield the…

医学物理 · 物理学 2007-05-23 Jose B. Almeida , Sandra Franco

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

图像与视频处理 · 电气工程与系统科学 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

Optical coherence tomography (OCT) is a prevalent imaging technique for retina. However, it is affected by multiplicative speckle noise that can degrade the visibility of essential anatomical structures, including blood vessels and tissue…

图像与视频处理 · 电气工程与系统科学 2021-07-12 Dewei Hu , Joseph D. Malone , Yigit Atay , Yuankai K. Tao , Ipek Oguz

Background: Human skin texture has yet to be quantified for diagnostic purposes. Here, the surface metrology of seborrheic keratoses is investigated with an optical profiler. Materials and Methods: Dermatologic specimens of 7 cadavers were…

组织与器官 · 定量生物学 2024-09-24 Nicole Werpachowski , Juliette Nutovits , Therese Limbana , John Goncalves , Alina Bridges , Brian Lee Beatty

Purpose: This study is to test the feasibility of optical coherence tomography (OCT) detection of photoreceptor abnormality and to verify the photoreceptor abnormality is rod predominated in early DR . Methods: OCT images were acquired from…

定量方法 · 定量生物学 2021-12-16 David Le , Taeyoon Son , Jennifer I. Lim , Xincheng Yao

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Corneal thickness (pachymetry) maps can be used to monitor restoration of corneal endothelial function, for example after Descemet's membrane endothelial keratoplasty (DMEK). Automated delineation of the corneal interfaces in anterior…

Objective: The mechanical properties of corneal tissues play a crucial role in determining corneal shape and have significant implications in vision care. This study aimed to address the challenge of obtaining accurate in vivo data for the…

医学物理 · 物理学 2023-07-11 Guo-Yang Li , Xu Feng , Seok-Hyun Yun

High-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers…

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