相关论文: Operating Principles of Peristaltic Pumping throug…
Low Reynolds number flow near a poroelastic interface can be found across scales in biological and engineered systems. We develop a 2D model of peristaltic flow confined under a poroelastic solid. In this geometry, the lower boundary is an…
Directional fluid flow in perivascular spaces surrounding cerebral arteries is hypothesized to play a key role in brain solute transport and clearance. While various drivers for pulsatile flow, such as cardiac or respiratory pulsations, are…
Peristalsis is the driving mechanism behind a broad array of biological and engineered flows. In peristaltic pumping, a wave-like contraction of the tube wall produces local changes in volume which induce flow. Net flow arises due to…
Two-dimensional laminar flow of a viscous fluid induced by peristalsis due to a moving wall wave has been studied previously for a rectangular channel, a circular tube, and a concentric circular annulus. Here we study peristaltic flow in a…
The flow of cerebrospinal fluid through the perivascular spaces of the brain is believed to play a crucial role in eliminating toxic waste proteins. While the driving forces of this flow have been enigmatic, experiments have shown that…
Peristaltic pumping is hypothesized to drive fluid transport in several physiological systems, including cerebrospinal fluid flow through cerebral perivascular spaces (PVSs). Cerebral PVSs are unique in the context of peristaltic pumping…
The asymptotic derivation of a new family of one-dimensional, weakly nonlinear and weakly dispersive equations that model the flow of an ideal fluid in an elastic vessel is presented. Dissipative effects due to the viscous nature of the…
The paper presents a new type of weakly nonlinear two-scale model of controllable periodic porous piezoelectric structures saturated by Newtonian fluids. The flow is propelled by peristaltic deformation of microchannels which is induced due…
Pumping at low Reynolds number is a ubiquitously encountered feature, both in biological organisms and engineered devices. Generating net flow requires the presence of an asymmetry in the system, which traditionally comes from geometric…
We apply the lubrication approximation to solve for the flow generated by a peristaltic traveling wave in a finite, planar channel, and examine the effect of channel length. Cerebrospinal fluid (CSF) is hypothesized to be peristaltically…
A nonlinear model relating the imposed motion of a circular cylinder, submerged in a fluid flow, to the transverse force coefficient is presented. The nonlinear fluid system, featuring vortex shedding patterns, limit cycle oscillations and…
Valveless pumping assists in fluid transport in various organisms and engineering systems. In a previous work, to study the actuator impact effects on valveless pumping, we constructed a piecewise-linear lumped-parameter model for a…
Balloon dilation catheters are often used to quantify the physiological state of peristaltic activity in tubular organs and comment on their ability to propel fluid which is important for healthy human function. To fully understand this…
There is an emerging class of microfluidic bioreactors which possess long-term, closed circuit perfusion under sterile conditions with in vivo-like flow parameters. Integrated into microfluidics, peristaltic-like pneumatically actuated…
This study presents a first-principles model to predict the two-phase pressure drop in gas-liquid intermittent flow through round capillaries, which serve as the simplest analogous of a porous medium. Building upon the classical capillary…
The slow viscous flow through a doubly-periodic array of cylinders does not have an analytical solution. However, as a reduced model for the flow within fibrous porous media, this solution is important for many real-world systems. We…
Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…
Devising optimal interventions for constraining stochastic systems is a challenging endeavour that has to confront the interplay between randomness and nonlinearity. Existing methods for identifying the necessary dynamical adjustments…
We study the buckling of a clamped beam immersed in a creeping flow within a rectangular channel. Via a combination of precision experiments, simulations, and theoretical modeling, we show how the instability depends on a pressure feedback…
We investigate both experimentally and theoretically the traffic of particles flowing in microfluidic obstacle networks. We show that the traffic dynamics is a non-linear process: the particle current does not scale with the particle…