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Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric…

机器学习 · 计算机科学 2024-02-28 Giovanna Maria Dimitri , Simeon Spasov , Andrea Duggento , Luca Passamonti , Pietro Li`o , Nicola Toschi

Generative models capable of capturing nuanced clinical features in medical images hold great promise for facilitating clinical data sharing, enhancing rare disease datasets, and efficiently synthesizing annotated medical images at scale.…

图像与视频处理 · 电气工程与系统科学 2023-06-23 Shenghuan Sun , Gregory M. Goldgof , Atul Butte , Ahmed M. Alaa

We develop a general framework unifying several gradient-based stochastic optimization methods for empirical risk minimization problems both in centralized and distributed scenarios. The framework hinges on the introduction of an augmented…

最优化与控制 · 数学 2022-07-11 Yan Huang , Ying Sun , Zehan Zhu , Changzhi Yan , Jinming Xu

The improved diagnostic accuracy of ultrasound breast examinations remains an important goal. In this study, we propose a biophysical feature based machine learning method for breast cancer detection to improve the performance beyond a…

图像与视频处理 · 电气工程与系统科学 2022-07-15 Jihye Baek , Avice M. O'Connell , Kevin J. Parker

In this work, we study the problem pertaining to personalized classification of subclinical atherosclerosis by developing a hierarchical graph neural network framework to leverage two characteristic modalities of a patient: clinical…

机器学习 · 计算机科学 2025-09-15 Irsyad Adam , Steven Swee , Erika Yilin , Ethan Ji , William Speier , Dean Wang , Alex Bui , Wei Wang , Karol Watson , Peipei Ping

The medical research facilitates to acquire a diverse type of data from the same individual for particular cancer. Recent studies show that utilizing such diverse data results in more accurate predictions. The major challenge faced is how…

基因组学 · 定量生物学 2017-10-11 Jaya Thomas , Lee Sael

Automatic report generation has arisen as a significant research area in computer-aided diagnosis, aiming to alleviate the burden on clinicians by generating reports automatically based on medical images. In this work, we propose a novel…

计算机视觉与模式识别 · 计算机科学 2024-06-04 Jun Li , Tongkun Su , Baoliang Zhao , Faqin Lv , Qiong Wang , Nassir Navab , Ying Hu , Zhongliang Jiang

The assessment of imaging biomarkers is critical for advancing precision medicine and improving disease characterization. Despite the availability of methods to derive disease heterogeneity metrics in imaging studies, a robust framework for…

Novel multimodal imaging methods are capable of generating extensive, super high resolution datasets for preclinical research. Yet, a massive lack of annotations prevents the broad use of deep learning to analyze such data. So far, existing…

图像与视频处理 · 电气工程与系统科学 2021-04-26 Izabela Horvath , Johannes C. Paetzold , Oliver Schoppe , Rami Al-Maskari , Ivan Ezhov , Suprosanna Shit , Hongwei Li , Ali Ertuerk , Bjoern H. Menze

The integration of multi-modal data, such as pathological images and genomic data, is essential for understanding cancer heterogeneity and complexity for personalized treatments, as well as for enhancing survival predictions. Despite the…

定量方法 · 定量生物学 2023-01-09 Lin Qiu , Aminollah Khormali , Kai Liu

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

图像与视频处理 · 电气工程与系统科学 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray…

人工智能 · 计算机科学 2016-12-14 Rajendra Rana Bhat , Vivek Viswanath , Xiaolin Li

Wearable sensor data offer opportunities for personalized health monitoring, yet deriving actionable insights from their complex, longitudinal data streams is challenging. This paper introduces a framework to learn personalized…

机器学习 · 计算机科学 2025-08-21 Ajan Subramanian , Amir M. Rahmani

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

计算与语言 · 计算机科学 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki

Due to the complexity of the human body, most diseases present a high inter-personal variability in the way they manifest, i.e. in their phenotype, which has important clinical repercussions - as for instance the difficulty in defining…

物理与社会 · 物理学 2018-06-06 Massimiliano Zanin , Juan Manuel Tuñas , Ernestina Menasalvas

In anti-cancer drug development, a major scientific challenge is disentangling the complex relationships between high-dimensional genomics data from patient tumor samples, the corresponding tumor's organ of origin, the drug targets…

机器学习 · 计算机科学 2024-03-29 Omid Bazgir , Zichen Wang , Ji Won Park , Marc Hafner , James Lu

Medical imaging plays a pivotal role in diagnosis and treatment in clinical practice. Inspired by the significant progress in automatic image captioning, various deep learning (DL)-based methods have been proposed to generate radiology…

计算机视觉与模式识别 · 计算机科学 2022-02-04 Yixin Wang , Zihao Lin , Zhe Xu , Haoyu Dong , Jiang Tian , Jie Luo , Zhongchao Shi , Yang Zhang , Jianping Fan , Zhiqiang He

The increase in high-dimensional multiomics data demands advanced integration models to capture the complexity of human diseases. Graph-based deep learning integration models, despite their promise, struggle with small patient cohorts and…

机器学习 · 计算机科学 2024-08-07 Sina Tabakhi , Charlotte Vandermeulen , Ian Sudbery , Haiping Lu

Radiology report generation (RRG) aims to automatically produce diagnostic reports from medical images, with the potential to enhance clinical workflows and reduce radiologists' workload. While recent approaches leveraging multimodal large…

人工智能 · 计算机科学 2025-05-16 Ziruo Yi , Ting Xiao , Mark V. Albert

Machine learning (ML) is increasingly being used in image retrieval systems for medical decision making. One application of ML is to retrieve visually similar medical images from past patients (e.g. tissue from biopsies) to reference when…