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Owing to the advantages of increased accuracy and the potential to detect unseen patterns, provided by data mining techniques they have been widely incorporated for standard classification problems. They have often been used for high…

机器学习 · 计算机科学 2022-10-05 Anirudha Rayasam , Nagamma Patil

Deep learning models have demonstrated superior performance in several application problems, such as image classification and speech processing. However, creating a deep learning model using health record data requires addressing certain…

机器学习 · 计算机科学 2021-12-14 Amirsina Torfi , Edward A. Fox , Chandan K. Reddy

Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able…

机器学习 · 计算机科学 2022-05-02 Wouter A. C. van Amsterdam , Marinus J. C. Eijkemans

Despite considerable progress in developing artificial intelligence (AI) algorithms for prostate cancer detection from whole slide images, the clinical applicability of these models remains limited due to variability in pathological…

组织与器官 · 定量生物学 2024-06-12 T. J. Hart , Chloe Engler Hart , Spencer Hopson , Paul M. Urie , Dennis Della Corte

The performance of supervised deep learning algorithms depends significantly on the scale, quality and diversity of the data used for their training. Collecting and manually annotating large amount of data can be both time-consuming and…

计算机视觉与模式识别 · 计算机科学 2021-07-02 C. Symeonidis , P. Nousi , P. Tosidis , K. Tsampazis , N. Passalis , A. Tefas , N. Nikolaidis

A broad spectrum of data from different modalities are generated in the healthcare domain every day, including scalar data (e.g., clinical measures collected at hospitals), tensor data (e.g., neuroimages analyzed by research institutes),…

机器学习 · 计算机科学 2018-03-28 Bokai Cao

In the context of personalized medicine, text mining methods pose an interesting option for identifying disease-gene associations, as they can be used to generate novel links between diseases and genes which may complement knowledge from…

计算与语言 · 计算机科学 2017-09-28 Hendrik ter Horst , Matthias Hartung , Roman Klinger , Matthias Zwick , Philipp Cimiano

Accurate prediction of recurrence in clear cell renal cell carcinoma (ccRCC) remains a major clinical challenge due to the disease complex molecular, pathological, and clinical heterogeneity. Traditional prognostic models, which rely on…

图像与视频处理 · 电气工程与系统科学 2025-07-11 Hasaan Maqsood , Saif Ur Rehman Khan

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

Deep Research agents driven by LLMs have automated the scholarly discovery pipeline, from planning and query formulation to iterative web exploration. Yet they remain constrained by a static, ``one-size-fits-all'' retrieval paradigm.…

信息检索 · 计算机科学 2026-05-12 Xiaopeng Li , Wenlin Zhang , Yingyi Zhang , Pengyue Jia , Yejing Wang , Yichao Wang , Yong Liu , Huifeng Guo , Xiangyu Zhao

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

计算机视觉与模式识别 · 计算机科学 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

In many applications, data can be heterogeneous in the sense of spanning latent groups with different underlying distributions. When predictive models are applied to such data the heterogeneity can affect both predictive performance and…

机器学习 · 统计学 2022-05-04 Thomas Lartigue , Sach Mukherjee

Understanding the factors that trigger or prevent undesirable health outcomes across patient subpopulations is essential for designing targeted interventions. While randomized controlled trials and expert-led patient interviews are standard…

人工智能 · 计算机科学 2026-05-28 Shishir Adhikari , Guido Muscioni , Mark Shapiro , Plamen Petrov , Elena Zheleva

Radiogenomics is an emerging field in cancer research that combines medical imaging data with genomic data to predict patients clinical outcomes. In this paper, we propose a multivariate sparse group lasso joint model to integrate imaging…

统计方法学 · 统计学 2022-06-06 Tiantian Zeng , Md Selim , Jie Zhang , Arnold Stromberg , Jin Chen , Chi Wang

Though deep learning has shown successful performance in classifying the label and severity stage of certain disease, most of them give few evidence on how to make prediction. Here, we propose to exploit the interpretability of deep…

计算机视觉与模式识别 · 计算机科学 2020-03-16 Yuhao Niu , Lin Gu , Feng Lu , Feifan Lv , Zongji Wang , Imari Sato , Zijian Zhang , Yangyan Xiao , Xunzhang Dai , Tingting Cheng

Important objectives in cancer research are the prediction of a patient's risk based on molecular measurements such as gene expression data and the identification of new prognostic biomarkers (e.g. genes). In clinical practice, this is…

应用统计 · 统计学 2020-04-17 Katrin Madjar , Manuela Zucknick , Katja Ickstadt , Jörg Rahnenführer

Multi-source spatial point data prediction is crucial in fields like environmental monitoring and natural resource management, where integrating data from various sensors is the key to achieving a holistic environmental understanding.…

机器学习 · 计算机科学 2024-07-02 Dazhou Yu , Xiaoyun Gong , Yun Li , Meikang Qiu , Liang Zhao

Rapid technological advances have allowed for molecular profiling across multiple omics domains from a single sample for clinical decision making in many diseases, especially cancer. As tumor development and progression are dynamic…

统计方法学 · 统计学 2022-02-11 Dongyan Yan , Subharup Guha

Metastasis is the leading cause of cancer-related mortality, yet most predictive models rely on shallow architectures and neglect patient-specific regulatory mechanisms. Here, we integrate classical machine learning and deep learning to…

其他定量生物学 · 定量生物学 2025-12-29 Jiwei Fu , Chunyu Yang

The complexity and variability inherent in high-resolution pathological images present significant challenges in computational pathology. While pathology foundation models leveraging AI have catalyzed transformative advancements, their…

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