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The Cancer Genome Atlas (TCGA) has enabled novel discoveries and served as a large-scale reference dataset in cancer through its harmonized genomics, clinical, and imaging data. Numerous prior studies have developed bespoke deep learning…

机器学习 · 计算机科学 2026-05-11 Steven Song , Morgan Borjigin-Wang , Irene Madejski , Robert L. Grossman

The development of robust deep learning models for breast ultrasound (BUS) image analysis is significantly constrained by the scarcity of expert-annotated data. To address this limitation, we propose a clinically controllable generative…

图像与视频处理 · 电气工程与系统科学 2025-07-11 Haoyu Pan , Hongxin Lin , Zetian Feng , Chuxuan Lin , Junyang Mo , Chu Zhang , Zijian Wu , Yi Wang , Qingqing Zheng

Diagnostic imaging has gained prominence as potential biomarkers for early detection and diagnosis in a diverse array of disorders including cancer. However, existing methods routinely face challenges arising from various factors such as…

Knowledge based dialogue systems have attracted increasing research interest in diverse applications. However, for disease diagnosis, the widely used knowledge graph is hard to represent the symptom-symptom relations and symptom-disease…

计算与语言 · 计算机科学 2020-12-29 Xinyan Zhao , Liangwei Chen , Huanhuan Chen

Personalization aims to characterize individual preferences and is widely applied across many fields. However, conventional personalized methods operate in a centralized manner, potentially exposing raw data when pooling individual…

机器学习 · 计算机科学 2025-08-06 Hao Di , Yi Yang , Haishan Ye , Xiangyu Chang

Tailoring treatment assignment to specific individuals can improve the health outcomes, but a single study may offer inadequate information for this purpose. The ability to leverage information from an auxiliary data source deemed to be…

统计方法学 · 统计学 2025-02-05 Ashwini Venkatasubramaniam , Julian Wolfson

Synthetic datasets are important for evaluating and testing machine learning models. When evaluating real-life recommender systems, high-dimensional categorical (and sparse) datasets are often considered. Unfortunately, there are not many…

信息检索 · 计算机科学 2024-12-11 Miha Malenšek , Blaž Škrlj , Blaž Mramor , Jure Demšar

Every year physicians face an increasing demand of image-based diagnosis from patients, a problem that can be addressed with recent artificial intelligence methods. In this context, we survey works in the area of automatic report generation…

计算机视觉与模式识别 · 计算机科学 2022-01-11 Pablo Messina , Pablo Pino , Denis Parra , Alvaro Soto , Cecilia Besa , Sergio Uribe , Marcelo andía , Cristian Tejos , Claudia Prieto , Daniel Capurro

There is a growing need for flexible general frameworks that integrate individual-level data with external summary information for improved statistical inference. External information relevant for a risk prediction model may come in…

统计方法学 · 统计学 2023-04-11 Tian Gu , Jeremy M. G. Taylor , Bhramar Mukherjee

Automatic radiology report generation can alleviate the workload for physicians and minimize regional disparities in medical resources, therefore becoming an important topic in the medical image analysis field. It is a challenging task, as…

计算机视觉与模式识别 · 计算机科学 2025-03-07 Xinyi Wang , Grazziela Figueredo , Ruizhe Li , Wei Emma Zhang , Weitong Chen , Xin Chen

Routine clinical visits of a patient produce not only image data, but also non-image data containing clinical information regarding the patient, i.e., medical data is multi-modal in nature. Such heterogeneous modalities offer different and…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Sein Kim , Namkyeong Lee , Junseok Lee , Dongmin Hyun , Chanyoung Park

In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is a heterogeneous disease. Examining similarity and difference in the genetic basis of multiple subtypes of…

统计方法学 · 统计学 2013-04-18 Jin Liu , Jian Huang , Yawei Zhang , Qing Lan , Nathaniel Rothman , Tongzhang Zheng , Shuangge Ma

Assessing the quality of cancer care administered by US health providers poses numerous challenges due to meaningful heterogeneity in patient populations. Patients undergoing oncology treatment exhibit substantial variation in disease…

应用统计 · 统计学 2025-02-17 Yige Li , Nancy L. Keating , Mary Beth Landrum , Jose R. Zubizarreta

Prognostic task is of great importance as it closely related to the survival analysis of patients, the optimization of treatment plans and the allocation of resources. The existing prognostic models have shown promising results on specific…

图像与视频处理 · 电气工程与系统科学 2025-01-14 Binyu Zhang , Shichao Li , Junpeng Jian , Zhu Meng , Limei Guo , Zhicheng Zhao

Recent advancements in generative models have significantly facilitated the development of personalized content creation. Given a small set of images with user-specific concept, personalized image generation allows to create images that…

计算机视觉与模式识别 · 计算机科学 2025-02-19 Yuxiang Wei , Yiheng Zheng , Yabo Zhang , Ming Liu , Zhilong Ji , Lei Zhang , Wangmeng Zuo

Recent technological advancements have enabled detailed investigation of associations between the molecular architecture and tumor heterogeneity, through multi-source integration of radiological imaging and genomic (radiogenomic) data. In…

Heterogeneity is a fundamental characteristic of cancer. To accommodate heterogeneity, subgroup identification has been extensively studied and broadly categorized into unsupervised and supervised analysis. Compared to unsupervised…

统计方法学 · 统计学 2026-02-25 Xing Qin , Xu Liu , Shuangge Ma , Mengyun Wu

Mining Electronic Health Records (EHRs) becomes a promising topic because of the rich information they contain. By learning from EHRs, machine learning models can be built to help human experts to make medical decisions and thus improve…

机器学习 · 计算机科学 2021-01-19 Zheng Liu , Xiaohan Li , Hao Peng , Lifang He , Philip S. Yu

Revealing relationships between genes and disease phenotypes is a critical problem in biomedical studies. This problem has been challenged by the heterogeneity of diseases. Patients of a perceived same disease may form multiple subgroups,…

统计方法学 · 统计学 2022-11-30 Yifan Sun , Ziye Luo , Xinyan Fan

Multimodal pathology-genomic analysis has become increasingly prominent in cancer survival prediction. However, existing studies mainly utilize multi-instance learning to aggregate patch-level features, neglecting the information loss of…

计算机视觉与模式识别 · 计算机科学 2025-05-21 Mingcheng Qu , Guang Yang , Donglin Di , Tonghua Su , Yue Gao , Yang Song , Lei Fan