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Accurate prediction of cardiovascular disease (CVD) risk is crucial for healthcare institutions. This study addresses the growing prevalence of diabetes and its strong link to heart disease by proposing an efficient CVD risk prediction…

机器学习 · 计算机科学 2025-11-10 Esha Chowdhury

A high-risk pregnancy is a pregnancy complicated by factors that can adversely affect the outcomes of the mother or the infant. Health insurers use algorithms to identify members who would benefit from additional clinical support. This work…

Viewing the trajectory of a patient as a dynamical system, a recurrent neural network was developed to learn the course of patient encounters in the Pediatric Intensive Care Unit (PICU) of a major tertiary care center. Data extracted from…

机器学习 · 统计学 2017-01-25 M Aczon , D Ledbetter , L Ho , A Gunny , A Flynn , J Williams , R Wetzel

Risk scores are widely used for clinical decision making and commonly generated from logistic regression models. Machine-learning-based methods may work well for identifying important predictors, but such 'black box' variable selection…

机器学习 · 计算机科学 2024-12-31 Yilin Ning , Siqi Li , Marcus Eng Hock Ong , Feng Xie , Bibhas Chakraborty , Daniel Shu Wei Ting , Nan Liu

Stroke affected millions annually, yet poor symptom recognition often delayed care-seeking. To address risk recognition gap, we developed a passive surveillance system for early stroke risk detection using patient-reported symptoms among…

Decision-making related to health is complex. Machine learning (ML) and patient generated data can identify patterns and insights at the individual level, where human cognition falls short, but not all ML-generated information is of equal…

应用统计 · 统计学 2021-01-15 Elliot G Mitchell , Esteban G Tabak , Matthew E Levine , Lena Mamykina , David J Albers

Over the last century, risk scores have been the most popular form of predictive model used in healthcare and criminal justice. Risk scores are sparse linear models with integer coefficients; often these models can be memorized or placed on…

机器学习 · 计算机科学 2022-10-13 Jiachang Liu , Chudi Zhong , Boxuan Li , Margo Seltzer , Cynthia Rudin

Intensive Care Unit (ICU) mortality prediction, which estimates a patient's mortality status at discharge using EHRs collected early in an ICU admission, is vital in critical care. For this task, predictive accuracy alone is insufficient;…

机器学习 · 计算机科学 2025-10-15 Qingwen Li , Xiaohang Zhao , Xiao Han , Hailiang Huang , Lanjuan Liu

Uncertainty quantification of causal effects is crucial for safety-critical applications such as personalized medicine. A powerful approach for this is conformal prediction, which has several practical benefits due to model-agnostic…

We investigate a long-debated question, which is how to create predictive models of recidivism that are sufficiently accurate, transparent, and interpretable to use for decision-making. This question is complicated as these models are used…

机器学习 · 统计学 2020-10-20 Jiaming Zeng , Berk Ustun , Cynthia Rudin

Existing prognostic tools mainly focus on predicting the risk of mortality among patients with coronavirus disease 2019. However, clinical evidence suggests that COVID-19 can result in non-mortal complications that affect patient prognosis.…

Machine Learning (ML) models are often complex and difficult to interpret due to their 'black-box' characteristics. Interpretability of a ML model is usually defined as the degree to which a human can understand the cause of decisions…

统计方法学 · 统计学 2020-06-25 Simon Kocbek , Primoz Kocbek , Leona Cilar , Gregor Stiglic

Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

机器学习 · 计算机科学 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

Patients resuscitated from cardiac arrest (CA) face a high risk of neurological disability and death, however pragmatic methods are lacking for accurate and reliable prognostication. The aim of this study was to build computational models…

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

人工智能 · 计算机科学 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee

Adversarial examples pose a security threat to many critical systems built on neural networks (such as face recognition systems, and self-driving cars). While many methods have been proposed to build robust models, how to build certifiably…

机器学习 · 计算机科学 2023-09-06 Ruihan Zhang , Peixin Zhang , Jun Sun

Introduction: An approach to building a hybrid simulation of patient flow is introduced with a combination of data-driven methods for automation of model identification. The approach is described with a conceptual framework and basic…

计算机与社会 · 计算机科学 2020-04-03 Sergey V. Kovalchuk , Anastasia A. Funkner , Oleg G. Metsker , Aleksey N. Yakovlev

Although recent multi-task learning methods have shown to be effective in improving the generalization of deep neural networks, they should be used with caution for safety-critical applications, such as clinical risk prediction. This is…

机器学习 · 计算机科学 2021-02-19 A. Tuan Nguyen , Hyewon Jeong , Eunho Yang , Sung Ju Hwang

Clinical prediction models are increasingly used to support patient care, yet many deep learning-based approaches remain unstable, as their predictions can vary substantially when trained on different samples from the same population. Such…

机器学习 · 计算机科学 2026-02-13 Sara Matijevic , Christopher Yau

Sudden cardiac death (SCD) is unpredictable, and its prediction in Chagas cardiomyopathy (CC) remains a significant challenge, especially in patients not classified as high risk. While AI and machine learning models improve risk…