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相关论文: Toward Personalized Medicine in Connectomic Deep B…

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Parkinson's Disease afflicts millions of individuals globally. Emerging as a promising brain rehabilitation therapy for Parkinson's Disease, Closed-loop Deep Brain Stimulation (CL-DBS) aims to alleviate motor symptoms. The CL-DBS system…

神经与进化计算 · 计算机科学 2024-07-26 Ananna Biswas , Hongyu An

Deep brain stimulation (DBS) is an effective therapy as an alternative to pharmaceutical treatments for Parkinson's disease (PD). Aside from factors such as instrumentation, treatment plans, and surgical protocols, the success of the…

图像与视频处理 · 电气工程与系统科学 2024-10-30 Yiming Xiao , Jonathan C. Lau , Dimuthu Hemachandra , Greydon Gilmore , Ali R. Khan , Terry M. Peters

This paper presents the results of our recent work on studying the effects of deep brain stimulation (DBS) and medication on the dynamics of brain local field potential (LFP) signals used for behavior analysis of patients with Parkinson s…

神经元与认知 · 定量生物学 2018-04-11 Hosein M. Golshan , Adam O. Hebb , Joshua Nedrud , Mohammad H. Mahoor

Advancements in neurosurgical robotics have improved medical procedures, particularly deep brain stimulation, where robots combine human and machine intelligence to precisely implant electrodes in the brain. While effective, this procedure…

系统与控制 · 电气工程与系统科学 2023-12-14 Mobina Zibandepour , Akram Shojaei , Arash Abbasi Larki , Mehdi Delrobaei

Transcranial Electrical Stimulation (TCES) and Deep Brain Stimulation (DBS) are two different applications of electrical current to the brain used in different areas of medicine. Both have a similar frequency dependence of their efficiency,…

神经元与认知 · 定量生物学 2019-07-15 Markus Schütt , Jens Christian Claussen

Health management has become a primary problem as new kinds of diseases and complex symptoms are introduced to a rapidly growing modern society. Building a better and smarter healthcare infrastructure is one of the ultimate goals of a smart…

机器学习 · 计算机科学 2025-03-24 Chu Myaet Thwal , Kyi Thar , Ye Lin Tun , Choong Seon Hong

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

神经元与认知 · 定量生物学 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor

Deep brain stimulation (DBS) is an established intervention for Parkinson's disease (PD), but conventional open-loop systems lack adaptability, are energy-inefficient due to continuous stimulation, and provide limited personalization to…

机器学习 · 计算机科学 2025-07-10 Harsh Ravivarapu , Gaurav Bagwe , Xiaoyong Yuan , Chunxiu Yu , Lan Zhang

The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation,…

Deep brain stimulation (DBS) can alleviate the movement disorders like Parkinson's disease (PD). Indeed, it is known that aberrant beta (13-30Hz)oscillations and the loss of dopaminergic neurons in the basal ganglia-thalamus (BGTH) and…

神经元与认知 · 定量生物学 2021-12-07 Hina Shaheen , Roderick Melnik

Deep Brain Stimulation (DBS) is a therapy widely used for treating the symptoms of neurological disorders. Electrical pulses are chronically delivered in DBS to a disease-specific brain target via a surgically implanted electrode. The…

系统与控制 · 电气工程与系统科学 2024-10-24 Anna Franziska Frigge , Elena Jiltsova , Fredrik Olsson , Dag Nyholm , Alexander Medvedev

Deep Brain Stimulation (DBS) is a highly effective treatment for Parkinson's Disease (PD). Recent research uses reinforcement learning (RL) for DBS, with RL agents modulating the stimulation frequency and amplitude. But, these models rely…

A deep neural network (DNN) that can reliably model muscle responses from corresponding brain stimulation has the potential to increase knowledge of coordinated motor control for numerous basic science and applied use cases. Such cases…

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

系统与控制 · 电气工程与系统科学 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari

Functional brain network analysis has become an indispensable tool for brain disease analysis. It is profoundly impacted by deep learning methods, which can characterize complex connections between ROIs. However, the research on foundation…

图像与视频处理 · 电气工程与系统科学 2025-08-08 Yifei Tang , Hongjie Jiang , Changhong Jing , Hieu Pham , Shuqiang Wang

Deep brain stimulation (DBS) has shown great promise toward treating motor symptoms caused by Parkinson's disease (PD), by delivering electrical pulses to the Basal Ganglia (BG) region of the brain. However, DBS devices approved by the U.S.…

Objective. Personalized transcranial electrical stimulation (tES) has gained growing attention due to the substantial inter-individual variability in brain anatomy and physiology. While previous reviews have discussed the physiological…

神经元与认知 · 定量生物学 2025-11-06 Mo Wang , Kexin Zheng , Yingyue Xin , Xiang Chen , Yiling Liu , Huichun Luo , Jingsheng Tang , Tifei Yuan , Hongkai Wen , Pengfei Wei , Quanying Liu

A major shortcoming of medical practice is the lack of an objective measure of conscious level. Impairment of consciousness is common, e.g. following brain injury and seizures, which can also interfere with sensory processing and volitional…

神经元与认知 · 定量生物学 2025-12-24 Alexis Pomares Pastor , Ines Ribeiro Violante , Gregory Scott

Mental disorders may exhibit pathological brain rhythms and neurostimulation promises to alleviate of patients' symptoms by modifying these rhythms. Today, most neurostimulation schemes are open-loop, i.e. administer experimental…

神经元与认知 · 定量生物学 2023-03-21 Thomas Wahl , Michel Duprez , Axel Hutt

Deep Brain Stimulation (DBS) is one of the most successful methods to diminish late-stage Parkinson's Disease (PD) symptoms. It is a delicate surgical procedure which requires detailed pre-surgical patient's study. High-field Magnetic…

图像与视频处理 · 电气工程与系统科学 2024-07-23 Tomás Lima , Igor Varga , Eduard Bakštein , Daniel Novák , Victor Alves