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The graphical lasso is a widely used algorithm for fitting undirected Gaussian graphical models. However, for inference on functionals of edge values in the learned graph, standard tools lack formal statistical guarantees, such as control…

统计方法学 · 统计学 2025-04-01 Sofia Guglielmini , Gerda Claeskens , Snigdha Panigrahi

The fused lasso, also known as (anisotropic) total variation denoising, is widely used for piecewise constant signal estimation with respect to a given undirected graph. The fused lasso estimate is highly nontrivial to compute when the…

We consider the problem of learning a structured multi-task regression, where the output consists of multiple responses that are related by a graph and the correlated response variables are dependent on the common inputs in a sparse but…

机器学习 · 统计学 2010-05-21 Xi Chen , Seyoung Kim , Qihang Lin , Jaime G. Carbonell , Eric P. Xing

We derive a new class of statistical tests for generalized linear models based on thresholding point estimators. These tests can be employed whether the model includes more parameters than observations or not. For linear models, our tests…

统计方法学 · 统计学 2018-03-14 Sylvain Sardy , Caroline Giacobino , Jairo Diaz-Rodriguez

In this paper, the fused graphical lasso (FGL) method is used to estimate multiple precision matrices from multiple populations simultaneously. The lasso penalty in the FGL model is a restraint on sparsity of precision matrices, and a…

统计理论 · 数学 2023-03-03 Qiuyan Zhang , Zhidong Bai , Lingrui Li , Hu Yang

This thesis studies two problems in modern statistics. First, we study selective inference, or inference for hypothesis that are chosen after looking at the data. The motiving application is inference for regression coefficients selected by…

机器学习 · 统计学 2015-07-02 Jason D. Lee

We consider the task of estimating a Gaussian graphical model in the high-dimensional setting. The graphical lasso, which involves maximizing the Gaussian log likelihood subject to an l1 penalty, is a well-studied approach for this task. We…

机器学习 · 统计学 2013-07-23 Kean Ming Tan , Daniela Witten , Ali Shojaie

Feature selection has been proven a powerful preprocessing step for high-dimensional data analysis. However, most state-of-the-art methods tend to overlook the structural correlation information between pairwise samples, which may…

机器学习 · 计算机科学 2019-07-02 Lu Bai , Lixin Cui , Yue Wang , Philip S. Yu , Edwin R. Hancock

We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important application of such tests is the detection of differentially…

定量方法 · 定量生物学 2014-05-16 Laurent Jacob , Pierre Neuvial , Sandrine Dudoit

We study tools for inference conditioned on model selection events that are defined by the generalized lasso regularization path. The generalized lasso estimate is given by the solution of a penalized least squares regression problem, where…

统计方法学 · 统计学 2016-06-14 Sangwon Hyun , Max G'Sell , Ryan J. Tibshirani

Graphical lasso is one of the most used estimators for inferring genetic networks. Despite its diffusion, there are several fields in applied research where the limits of detection of modern measurement technologies make the use of this…

统计方法学 · 统计学 2019-11-18 Luigi Augugliaro , Antonino Abbruzzo , Veronica Vinciotti

In this paper, we consider the problem of estimating multiple graphical models simultaneously using the fused lasso penalty, which encourages adjacent graphs to share similar structures. A motivating example is the analysis of brain…

机器学习 · 计算机科学 2014-01-03 Sen Yang , Zhaosong Lu , Xiaotong Shen , Peter Wonka , Jieping Ye

We propose a new algorithm for solving the graph-fused lasso (GFL), a method for parameter estimation that operates under the assumption that the signal tends to be locally constant over a predefined graph structure. Our key insight is to…

机器学习 · 统计学 2015-06-02 Wesley Tansey , James G. Scott

Detecting changepoints in a one-dimensional signal is a classical yet fundamental problem. The fused lasso provides an elegant convex formulation that produces a stepwise estimate of the mean, but quantifying the uncertainty of the detected…

统计理论 · 数学 2025-11-13 Rieko Tasaka , Tatsuya Kimura , Joe Suzuki

We present the group fused Lasso for detection of multiple change-points shared by a set of co-occurring one-dimensional signals. Change-points are detected by approximating the original signals with a constraint on the multidimensional…

定量方法 · 定量生物学 2011-06-23 Kevin Bleakley , Jean-Philippe Vert

We consider the problem of estimating multiple related but distinct graphical models on the basis of a high-dimensional data set with observations that belong to distinct classes. A motivating example occurs in the analysis of gene…

统计方法学 · 统计学 2012-07-12 Patrick Danaher , Pei Wang , Daniela M. Witten

We develop tools to do valid post-selective inference for a family of model selection procedures, including choosing a model via cross-validated Lasso. The tools apply universally when the following random vectors are jointly asymptotically…

统计方法学 · 统计学 2018-02-13 Jelena Markovic , Lucy Xia , Jonathan Taylor

We propose a novel method for estimating heterogeneous treatment effects based on the fused lasso. By first ordering samples based on the propensity or prognostic score, we match units from the treatment and control groups. We then run the…

In variable or graph selection problems, finding a right-sized model or controlling the number of false positives is notoriously difficult. Recently, a meta-algorithm called Stability Selection was proposed that can provide reliable…

机器学习 · 统计学 2017-12-14 George Philipp , Seunghak Lee , Eric P. Xing

We consider tests of significance in the setting of the graphical lasso for inverse covariance matrix estimation. We propose a simple test statistic based on a subsequence of the knots in the graphical lasso path. We show that this…

统计理论 · 数学 2013-07-24 Max Grazier G'Sell , Jonathan Taylor , Robert Tibshirani
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