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The term NeuralODE describes the structural combination of an Artifical Neural Network (ANN) and a numerical solver for Ordinary Differential Equations (ODEs), the former acts as the right-hand side of the ODE to be solved. This concept was…

机器学习 · 计算机科学 2022-09-09 Tobias Thummerer , Johannes Stoljar , Lars Mikelsons

Personalized virtual heart models have demonstrated increasing potential for clinical use, although the estimation of their parameters given patient-specific data remain a challenge. Traditional physics-based modeling approaches are…

信号处理 · 电气工程与系统科学 2024-03-26 Xiajun Jiang , Sumeet Vadhavkar , Yubo Ye , Maryam Toloubidokhti , Ryan Missel , Linwei Wang

To operate process engineering systems in a safe and reliable manner, predictive models are often used in decision making. In many cases, these are mechanistic first principles models which aim to accurately describe the process. In…

机器学习 · 计算机科学 2022-05-20 Timur Bikmukhametov , Johannes Jäschke

Models play an essential role in the design process of cyber-physical systems. They form the basis for simulation and analysis and help in identifying design problems as early as possible. However, the construction of models that comprise…

Design patterns provide a systematic way to convey solutions to recurring modeling challenges. This paper introduces design patterns for hybrid modeling, an approach that combines modeling based on first principles with data-driven modeling…

人工智能 · 计算机科学 2024-01-02 Maja Rudolph , Stefan Kurz , Barbara Rakitsch

The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…

Hybrid models composing mechanistic ODE-based dynamics with flexible and expressive neural network components have grown rapidly in popularity, especially in scientific domains where such ODE-based modeling offers important interpretability…

机器学习 · 计算机科学 2026-02-02 Bob Junyi Zou , Matthew E. Levine , Dessi P. Zaharieva , Ramesh Johari , Emily B. Fox

Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center…

图像与视频处理 · 电气工程与系统科学 2022-03-04 Akis Linardos , Kaisar Kushibar , Sean Walsh , Polyxeni Gkontra , Karim Lekadir

Computational cardiovascular flow modeling plays a crucial role in understanding blood flow dynamics. While 3D models provide acute details, they are computationally expensive, especially with fluid-structure interaction (FSI) simulations.…

流体动力学 · 物理学 2025-01-06 Hunor Csala , Arvind Mohan , Daniel Livescu , Amirhossein Arzani

Cardiovascular diseases are a leading cause of death in the world, driving the development of patient-specific and benchmark models for blood flow analysis. This chapter provides a theoretical overview of the main categories of Reduced…

In this review we make the statement that hybrid models in oncology are required as a mean for enhanced data integration. In the context of systems oncology, experimental and clinical data need to be at the heart of the models developments…

定量方法 · 定量生物学 2019-01-18 Angélique Stéphanou , Pascal Ballet , Gibin Powathil

Reduced-order models that accurately abstract high fidelity models and enable faster simulation is vital for real-time, model-based diagnosis applications. In this paper, we outline a novel hybrid modeling approach that combines machine…

信号处理 · 电气工程与系统科学 2020-03-06 Ion Matei , Johan de Kleer , Alexander Feldman , Rahul Rai , Souma Chowdhury

Hybrid modeling combining data-driven techniques and numerical methods is an emerging and promising research direction for efficient climate simulation. However, previous works lack practical platforms, making developing hybrid modeling a…

大气与海洋物理 · 物理学 2022-09-20 Xin Wang , Wei Xue , Yilun Han , Guangwen Yang

To understand and predict the performance of scientific applications, several analytical and machine learning approaches have been proposed, each having its advantages and disadvantages. In this paper, we propose and validate a hybrid…

性能 · 计算机科学 2019-02-27 Huda Ibeid , Siping Meng , Oliver Dobon , Luke Olson , William Gropp

Coronary heart disease (CHD) is a severe cardiac disease, and hence, its early diagnosis is essential as it improves treatment results and saves money on medical care. The prevailing development of quantum computing and machine learning…

机器学习 · 计算机科学 2024-10-02 Mehroush Banday , Sherin Zafar , Parul Agarwal , M Afshar Alam , Abubeker K M

Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…

医学物理 · 物理学 2026-04-21 Aaron L. Brown , Ju Liu , Daniel B. Ennis , Alison L. Marsden

In this paper we will address the problem of developing mathematical models for the numerical simulation of the human circulatory system. In particular, we will focus our attention on the problem of haemodynamics in large human arteries.

动力系统 · 数学 2007-05-23 Alfio Quarteroni

Cardiovascular disease (CVD) remains the foremost cause of mortality worldwide, underscoring the urgent need for intelligent and data-driven diagnostic tools. Traditional predictive models often struggle to generalize across heterogeneous…

人工智能 · 计算机科学 2026-01-27 Rajan Das Gupta , Xiaobin Wu , Xun Liu , Jiaqi He

Approaches to machine intelligence based on brain models have stressed the use of neural networks for generalization. Here we propose the use of a hybrid neural network architecture that uses two kind of neural networks simultaneously: (i)…

神经与进化计算 · 计算机科学 2008-10-01 Yuhua Chen , Subhash Kak , Lei Wang

This study proposed a hybrid model of a convolutional neural network (CNN) and a Transformer to predict and diagnose heart disease. Based on CNN's strength in detecting local features and the Transformer's high capacity in sensing global…

机器学习 · 计算机科学 2025-03-05 Ran Hao , Yanlin Xiang , Junliang Du , Qingyuan He , Jiacheng Hu , Ting Xu
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