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A swimming microorganism stirs the surrounding fluid, creating a flow field that governs not only its locomotion and nutrient uptake, but also its interactions with other microorganisms and the environment. Despite its fundamental…

Large groups of active cilia collectively beat in a fluid medium as metachronal waves, essential for some microorganisms motility and for flow generation in mucociliary clearance. Several models can predict the emergence of metachronal…

软凝聚态物质 · 物理学 2024-05-08 Supravat Dey , Gladys Massiera , Estelle Pitard

Immotile microbes inhabit nearly every environment on Earth, from soils and sediments to food matrices -- yet how they disperse through these physically confining environments is poorly understood. Here, we show that immotile microbial…

Epithelial cell clusters often move collectively on a substrate. Mechanical signals play a major role in organizing this behavior. There are a number of experimental observations in these systems which await a comprehensive explanation.…

生物物理 · 物理学 2021-01-22 Youyuan Deng , Herbert Levine , Xiaoming Mao , Leonard M. Sander

Cellular locomotion often involves the motion of thin, elastic filaments, such as cilia and flagella, in viscous environments. The manuscript serves as a general introduction to the topic of modelling microscale elastohydrodynamics. We…

软凝聚态物质 · 物理学 2024-10-15 Maciej Lisicki

We characterize cell motion in experiments and show that the transition to collective motion in colonies of gliding bacterial cells confined to a monolayer appears through the organization of cells into larger moving clusters. Collective…

We present a fast, high-throughput method for characterizing the motility of microorganisms in 3D based on standard imaging microscopy. Instead of tracking individual cells, we analyse the spatio-temporal fluctuations of the intensity in…

Microorganismal motility is often characterised by complex responses to environmental physico-chemical stimuli. Although the biological basis of these responses is often not well understood, their exploitation already promises novel avenues…

生物物理 · 物理学 2019-11-26 Jorge Arrieta , Marco Polin , Ramón Saleta-Piersanti , Idan Tuval

Suspensions of swimming micro-organisms provide examples of coordinated active dynamics. That has stimulated the study of a phenomenological theory combining synchronization and polar order in active matter. Here, we consider another…

软凝聚态物质 · 物理学 2019-04-08 M. Leoni

Many microswimmers are inherently chiral, and this chirality can introduce fascinating behaviors in a collection of microswimmers. The dynamics become even more intriguing when two types of microswimmers with distinct chirality are mixed.…

软凝聚态物质 · 物理学 2025-09-03 Divya Kushwaha , Shradha Mishra

The eukaryotic flagellum beats periodically, driven by the oscillatory dynamics of molecular motors, to propel cells and pump fluids. Small, but perceivable fluctuations in the beat of individual flagella have physiological implications for…

细胞行为 · 定量生物学 2015-06-18 Rui Ma , Gary S. Klindt , Ingmar H. Riedel-Kruse , Frank Jülicher , Benjamin M. Friedrich

Filamentous bacteriophages such as fd-like viruses are monodisperse rod-like colloids that have well defined properties: diameter, length, rigidity, charge and chirality. Engineering those viruses leads to a library of colloidal rods which…

软凝聚态物质 · 物理学 2017-12-06 Thomas Gibaud

Coordinated cilia are used throughout the natural world for micronscale fluid transport. They are often modelled with regular filament arrays on fixed, planar surfaces. Here, we simulate hundreds of interacting active filaments on spherical…

流体动力学 · 物理学 2021-12-01 Timothy A Westwood , Eric E Keaveny

The recent discovery of the striking sheet-like multicellular choanoflagellate species $Choanoeca~flexa$ that dynamically interconverts between two hemispherical forms of opposite orientation raises fundamental questions in cell and…

软凝聚态物质 · 物理学 2023-03-15 Lloyd Fung , Adam Konkol , Takuji Ishikawa , Ben Larson , Thibaut Brunet , Raymond E. Goldstein

A promising approach to transport cargo at the microscale lies within the use of self-propelled microorganisms, whose motion entrains that of passive particles. However, most applications remain limited to just a few passive particles of…

软凝聚态物质 · 物理学 2026-03-30 Taha Laroussi , Julien Bouvard , Etienne Jambon-Puillet , Mojtaba Jarrahi , Gabriel Amselem

It is now well established that nearby beating pairs of eukaryotic flagella or cilia typically synchronize in phase. A substantial body of evidence supports the hypothesis that hydrodynamic coupling between the active filaments, combined…

软凝聚态物质 · 物理学 2016-10-12 Raymond E. Goldstein , Eric Lauga , Adriana I. Pesci , Michael R. E. Proctor

Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

生物物理 · 物理学 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

Large ensembles of interacting, out-of-equilibrium agents are a paradigm of active matter. Their constituents' intrinsic activity may entail the spontaneous separation into localized phases of high and low densities. Motile microbes,…

Most motile bacteria swim in viscous fluids by rotating multiple helical flagellar filaments. These semi-rigid filaments repeatedly join ('bundle') and separate ('unbundle'), resulting in a two-gait random walk-like motion of the cell. In…

流体动力学 · 物理学 2020-11-18 Alexander Chamolly , Eric Lauga

We study a simple two-dimensional model for motion of an elastic filament subject to internally generated stresses and show that wave-like propagating shapes which can propel the filament can be induced by a self-organized mechanism via a…

软凝聚态物质 · 物理学 2019-08-17 S. Camalet , F. Julicher , J. Prost