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Cells have evolved efficient strategies to probe their surroundings and navigate through complex environments. From metastatic spread in the body to swimming cells in porous materials, escape through narrow constrictions - a key component…

生物物理 · 物理学 2021-10-04 Mathieu Souzy , Antoine Allard , Jean-François Louf , Matteo Contino , Idan Tuval , Marco Polin

Many biological microorganisms and artificial microswimmers react to external cues of environmental gradients by changing their swimming directions. We study here the behavior of eukarytic flagellated microswimmers in linear viscosity…

软凝聚态物质 · 物理学 2026-05-29 Shubham Anand , Jens Elgeti , Gerhard Gompper

The measurement of a quantitative and macroscopic parameter to estimate the global motility of a large population of swimming biological cells is a challenge Experiments on the rheology of active suspensions have been performed. Effective…

软凝聚态物质 · 物理学 2014-12-12 Salima Rafai , Levan Jibuti , Philippe Peyla

Ciliated tissues such as in the mammalian lungs, brains, and reproductive tracts, are specialized to pump fluid. They generate flows by the collective activity of hundreds of thousands of individual cilia that beat in a striking metachronal…

软凝聚态物质 · 物理学 2022-11-30 Anup Kanale , Feng Ling , Hanliang Guo , Sebastian Fuerthauer , Eva Kanso

Many-body interactions in systems of active matter can cause particles to move collectively and self-organize into dynamic structures with long-range order. In cells, the self-assembly of cytoskeletal filaments is critical for cellular…

软凝聚态物质 · 物理学 2020-05-26 Jeffrey M. Moore , Matthew A. Glaser , Meredith D. Betterton

Bacterial colonies are a well-known example of living active matter, exhibiting collective behaviors such as nematic alignment and collective motion that play an important role in the spread of microbial infections. While the underlying…

Flagellated microorganisms overcome the low-Reynolds-number time reversibility by rotating helical flagella. For peritrichous bacteria, such as Escherichia coli, the randomly distributed flagellar filaments align along the same direction to…

Bacteria exist in a free-swimming state or in a sessile biofilm state. The transition from free-swimming to sessile mode is characterized by changes in gene expression which alter, among others,the mechanics of flagellar motility. In this…

流体动力学 · 物理学 2014-05-07 Alan Cheng Hou Tsang , Eva Kanso

Organisms use hair-like cilia that beat in a metachronal fashion to actively transport fluid and suspended particles. Metachronal motion emerges due to a phase difference between beating cycles of neighboring cilia and appears as traveling…

流体动力学 · 物理学 2018-06-13 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

Swimming cells and microorganisms are as diverse in their collective dynamics as they are in their individual shapes and propulsion mechanisms. Even for sperm cells, which have a stereotyped shape consisting of a cell body connected to a…

流体动力学 · 物理学 2018-06-25 S. F. Schoeller , E. E. Keaveny

Cilia are ubiquitous organelles involves in eukaryotic motility. They are long, slender, and motile protrusions from the cell body. They undergo active regular oscillatory beating patterns that can propel cells, such as the algae…

亚细胞过程 · 定量生物学 2019-05-13 Pablo Sartori

Myxococcus xanthus is a model organism for studying bacterial social behaviors due to its ability to form complex multi-cellular structures. Knowledge of M. xanthus surface gliding motility and the mechanisms that coordinate it are…

Most bacteria are driven by the cilia or flagella, consisting of a long filament and a rotary molecular motor through a short flexible hook. The beating pattern of these filaments shows synchronization properties from hydrodynamic…

流体动力学 · 物理学 2023-11-23 Weiwei Su , Yuki Izumida , Hiroshi Kori

Adhesion-independent migration is a prominent mode of cell motility in confined environments, yet the physical principles that guide such movement remain incompletely understood. We present a phase-field model for simulating the motility of…

How motile bacteria move near a surface is a problem of fundamental biophysical interest and is key to the emergence of several phenomena of biological, ecological and medical relevance, including biofilm formation. Solid boundaries can…

生物物理 · 物理学 2019-09-12 Stanislaw Makarchuk , Vasco C. Braz , Nuno A. M. Araújo , Lena Ciric , Giorgio Volpe

The swimming properties of an E. coli-type model bacterium are investigated by mesoscale hy- drodynamic simulations, combining molecular dynamics simulations of the bacterium with the multiparticle particle collision dynamics method for the…

软凝聚态物质 · 物理学 2016-08-23 Jinglei Hu , Mingcheng Yang , Gerhard Gompper , Roland G. Winkler

Biological and robotic systems often operate in confined environments where material must be gathered without centralized control. Inspired by the effective collection strategies of aquatic worms (Lumbriculus variegatus and Tubifex…

软凝聚态物质 · 物理学 2025-05-09 R. Sinaasappel , K. R. Prathyusha , H. Tuazon , E. Mirzahossein , P. Illien , S. Bhamla , A. Deblais

We introduce a device developed to perform a 3D tracking of passive or active particles under flow, confined in a medium of hundreds micrometers wide. Micro-objects are placed inside a vertical glass capillary and two mirrors are set behind…

软凝聚态物质 · 物理学 2025-06-09 J. Moscatelli , X Benoit Gonin , F. Elias

Biased locomotion is a common feature of microorganisms, but little is known about its impact on self-organisation. Inspired by recent experiments showing a transition to large-scale flows, we study theoretically the dynamics of…

软凝聚态物质 · 物理学 2023-12-07 Albane Théry , Alexander Chamolly , Eric Lauga

Motile cilia drive biological fluid transport through whip-like beating motions that synchronize into metachronal waves. The lengths of these cilia span three orders of magnitude, from microns in human airways to millimeters in ctenophores.…