相关论文: Unifying incidence and prevalence under a time-var…

We introduce a new method for inference in stochastic epidemic models which uses recursive multinomial approximations to integrate over unobserved variables and thus circumvent likelihood intractability. The method is applicable to a class…

Due to its ability to summarise 'real-time' epidemic behaviour, the time-dependent reproduction number, Rt, is a useful metric for tracking pathogen transmission and quantifying the effects of interventions during infectious disease…

We introduce a kinetic framework for modeling the time evolution of the statistical distributions of the population densities in the three compartments of susceptible, infectious, and recovered individuals, under epidemic spreading driven…

Health-policy planning requires evidence on the burden that epidemics place on healthcare systems. Multiple, often dependent, datasets provide a noisy and fragmented signal from the unobserved epidemic process including transmission and…

Pandemics, like the 1918 Spanish Influenza and COVID-19, spread through regions of the World in subsequent waves. There is, however, no consensus on the origin of this pattern, which may originate from human behaviour rather than from the…

In most models of the spread of disease over contact networks it is assumed that the probabilities per unit time of disease transmission and recovery from disease are constant, implying exponential distributions of the time intervals for…

This study introduces a novel epidemiological model that expands upon the Kermack-McKendrick model by incorporating the age of infection and reinfection. By including infection age, we can classify participants, which enables a more…

We study the stochastic susceptible-infected-recovered (SIR) model with time-dependent forcing using analytic techniques which allow us to disentangle the interaction of stochasticity and external forcing. The model is formulated as a…

We consider in this paper a general SEIRS model describing the dynamics of an infectious disease including latency, waning immunity and infection-induced mortality. We derive an infinite system of differential equations that provides an…

In this paper we introduce a novel method to conduct inference with models defined through a continuous-time Markov process, and we apply these results to a classical stochastic SIR model as a case study. Using the inverse-size expansion of…

We study the relation between the age-specific prevalence, incidence and mortality in an illness-death model consisting of the three states Healthy, Ill, Dead. The dependency on three different time scales (age, calendar time, disease…

Compartmental epidemic models are among the most popular ones in epidemiology. For the parameters (e.g., the transmission rate) characterizing these models, the majority of researchers simplify them as constants, while some others manage to…

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

The effect of spatial correlations on the spread of infectious diseases was investigated using a stochastic SIR (Susceptible-Infective-Recovered) model on complex networks. It was found that in addition to the reduction of the effective…

Epidemiological models describe the spread of an infectious disease within a population. They capture microscopic details on how the disease is passed on among individuals in various different ways, while making predictions about the state…

A simple, but ``classical``, stochastic model for epidemic spread in a finite, but large, population is studied. The progress of the epidemic can be divided into three different phases that requires different tools to analyse. Initially the…

This paper discusses and analyzes a class of likelihood models which are based on two distributional innovations in financial models for stock returns. That is, the notion that the marginal distribution of aggregate returns of log-stock…

We investigate the global dynamics of a general Kermack-McKendrick-type epidemic model formulated in terms of a system of renewal equations. Specifically, we consider a renewal model for which both the force of infection and the infected…

Uncertainty can be classified as either aleatoric (intrinsic randomness) or epistemic (imperfect knowledge of parameters). The majority of frameworks assessing infectious disease risk consider only epistemic uncertainty. We only ever…

Stochastic epidemic models describe the dynamics of an epidemic as a disease spreads through a population. Typically, only a fraction of cases are observed at a set of discrete times. The absence of complete information about the time…