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相关论文: Predicting sepsis in multi-site, multi-national in…

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Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment…

机器学习 · 计算机科学 2022-07-15 Zeyu Wang , Huiying Zhao , Peng Ren , Yuxi Zhou , Ming Sheng

Machine learning has been widely used in healthcare applications to approximate complex models, for clinical diagnosis, prognosis, and treatment. As deep learning has the outstanding ability to extract information from time series, its true…

机器学习 · 计算机科学 2022-11-14 Ke Liao , Wei Wang , Armagan Elibol , Lingzhong Meng , Xu Zhao , Nak Young Chong

Sepsis is the leading cause of in-hospital mortality in the USA. Early sepsis onset prediction and diagnosis could significantly improve the survival of sepsis patients. Existing predictive models are usually trained on high-quality data…

机器学习 · 计算机科学 2024-07-25 Changchang Yin , Pin-Yu Chen , Bingsheng Yao , Dakuo Wang , Jeffrey Caterino , Ping Zhang

Postoperative stroke remains a critical complication in elderly surgical intensive care unit (SICU) patients, contributing to prolonged hospitalization, elevated healthcare costs, and increased mortality. Accurate early risk stratification…

定量方法 · 定量生物学 2025-06-05 Tinghuan Li , Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate predictions about patient state from clinical measurements has…

定量方法 · 定量生物学 2020-07-30 Dale Larie , Gary An , Chase Cockrell

Sepsis is a leading cause of mortality in intensive care units and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and there…

人工智能 · 计算机科学 2017-11-28 Aniruddh Raghu , Matthieu Komorowski , Imran Ahmed , Leo Celi , Peter Szolovits , Marzyeh Ghassemi

The progression of complex human diseases is associated with critical transitions across dynamical regimes. These transitions often spawn early-warning signals and provide insights into the underlying disease-driving mechanisms. In this…

定量方法 · 定量生物学 2019-10-24 Pejman F. Ghalati , Satya S. Samal , Jayesh S. Bhat , Robert Deisz , Gernot Marx , Andreas Schuppert

We present a machine learning pipeline and model that uses the entire uncurated EHR for prediction of in-hospital mortality at arbitrary time intervals, using all available chart, lab and output events, without the need for pre-processing…

机器学习 · 计算机科学 2019-09-18 Jacob Deasy , Pietro Liò , Ari Ercole

Background and Objectives: We aim to establish deep learning models to optimize the individualized energy delivery for septic patients. Methods and Study Design: We conducted a study of adult septic patients in Intensive Care Unit (ICU),…

其他定量生物学 · 定量生物学 2024-02-06 Lu Wang , Li Chang , Ruipeng Zhang , Kexun Li , Yu Wang , Wei Chen , Xuanlin Feng , Mingwei Sun , Qi Wang , Charles Damien Lu , Jun Zeng , Hua Jiang

Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying…

机器学习 · 计算机科学 2025-02-19 Bruno Petrungaro , Neville K. Kitson , Anthony C. Constantinou

Intensive care unit (ICU) is a crucial hospital department that handles life-threatening cases. Nowadays machine learning (ML) is being leveraged in healthcare ubiquitously. In recent years, management of ICU became one of the most…

机器学习 · 计算机科学 2025-05-26 Alexander Gabitashvili , Philipp Kellmeyer

Detecting and predicting septic shock early is crucial for the best possible outcome for patients. Accurately forecasting the vital signs of patients with sepsis provides valuable insights to clinicians for timely interventions, such as…

机器学习 · 计算机科学 2023-06-27 Anubhav Bhatti , Naveen Thangavelu , Marium Hassan , Choongmin Kim , San Lee , Yonghwan Kim , Jang Yong Kim

We present ICU-Sepsis, an environment that can be used in benchmarks for evaluating reinforcement learning (RL) algorithms. Sepsis management is a complex task that has been an important topic in applied RL research in recent years.…

机器学习 · 计算机科学 2025-03-12 Kartik Choudhary , Dhawal Gupta , Philip S. Thomas

Today's AI systems for medical decision support often succeed on benchmark datasets in research papers but fail in real-world deployment. This work focuses on the decision making of sepsis, an acute life-threatening systematic infection…

From 2017 to 2018 the number of scientific publications found via PubMed search using the keyword "Machine Learning" increased by 46% (4,317 to 6,307). The results of studies involving machine learning, artificial intelligence (AI), and big…

人工智能 · 计算机科学 2019-02-12 Russell Jeter , Christopher Josef , Supreeth Shashikumar , Shamim Nemati

Timely and interpretable early warning of sepsis remains a major clinical challenge due to the complex temporal dynamics of physiological deterioration. Traditional data-driven models often provide accurate yet opaque predictions, limiting…

机器学习 · 计算机科学 2026-04-24 Weizhi Nie , Zhen Qu , Weijie Wang , Chunpei Li , Ke Lu , Bingyang Zhou , Hongzhi Yu

Sepsis is a leading cause of mortality in intensive care units (ICUs), representing a substantial medical challenge. The complexity of analyzing diverse vital signs to predict sepsis further aggravates this issue. While deep learning…

机器学习 · 计算机科学 2024-05-24 Yuwei Liu , Chen Dan , Anubhav Bhatti , Bingjie Shen , Divij Gupta , Suraj Parmar , San Lee

Early identification of patients at risk for clinical deterioration in the intensive care unit (ICU) remains a critical challenge. Delayed recognition of impending adverse events, including mortality, vasopressor initiation, and mechanical…

机器学习 · 计算机科学 2026-03-17 Binesh Sadanandan

Few studies have investigated the diagnostic utilities of biomarkers for predicting bacteremia among septic patients admitted to intensive care units (ICU). Therefore, this study evaluated the prediction power of laboratory biomarkers to…

定量方法 · 定量生物学 2026-05-11 Sangwon Baek , Seung Jun Lee

Intensive care clinicians need reliable clinical practice tools to preempt unexpected critical events that might harm their patients in intensive care units (ICU), to pre-plan timely interventions, and to keep the patient's family well…