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To promote precision medicine, individualized treatment regimes (ITRs) are crucial for optimizing the expected clinical outcome based on patient-specific characteristics. However, existing ITR research has primarily focused on scenarios…
We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensity-modulated particle therapy (IMPT) treatment planning. Proton therapy…
We proposed a new approach, which is inspired by the method of super-resolution (SR) structured illumination microscopy (SIM) for overcoming the resolution limit in microscopy due to diffraction of light, for increasing the resolution of…
Owing to the edge preserving ability and low computational cost of the total variation (TV), variational models with the TV regularization have been widely investigated in the field of multiplicative noise removal. The key points of the…
In this paper, we investigate the continual learning of Vision Transformers (ViT) for the challenging exemplar-free scenario, with special focus on how to efficiently distill the knowledge of its crucial self-attention mechanism (SAM). Our…
In an era where the exponential growth of image data driven by the Internet of Things (IoT) is outpacing traditional storage solutions, this work explores and advances the potential of Implicit Neural Representation (INR) as a…
In this paper, we investigate protection strategies of sensitive body anatomy against the irradiation to the cancerous moving tumors in intensity modulated radiation therapy. Inspired by optimization techniques developed in statistical…
Although cone-beam CT (CBCT) has been used to guide irradiation for pre-clinical radiotherapy(RT) research, it is limited to localize soft tissue target especially in a low imaging contrast environment. Knowledge of target shape is a…
We propose a new superresolution imaging technique for interferometry using sparse modeling, utilizing two regularization terms: the $\ell_1$-norm and a new function named Total Squared Variation (TSV) of the brightness distribution. TSV is…
A key challenge of 360$^\circ$ VR video streaming is ensuring high quality with limited network bandwidth. Currently, most studies focus on tile-based adaptive bitrate streaming to reduce bandwidth consumption, where resources in network…
Video restoration (e.g., video super-resolution) aims to restore high-quality frames from low-quality frames. Different from single image restoration, video restoration generally requires to utilize temporal information from multiple…
The increasing interest in FLASH-RT has lead to the conversion of linear accelerators to enable ultra-high dose rate (UHDR) beams for preclinical research. Dosimetry hereof remains challenging with several crucial aspects missing. This work…
In this paper, we propose Total Variation Regularized Tensor-on-scalar Regression(TVTR), a novel method for estimating the association between a tensor outcome (a one dimensional or multidimensional array) and scalar predictors. While the…
The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radiation dose impossible. Digital breast tomosynthesis (DBT), a pseudo-3D technique, is now…
Invariant risk minimization (IRM) aims to enable out-of-distribution (OOD) generalization in deep learning by learning invariant representations. As IRM poses an inherently challenging bi-level optimization problem, most existing approaches…
Inferring causal individual treatment effect (ITE) from observational data is a challenging problem whose difficulty is exacerbated by the presence of treatment assignment bias. In this work, we propose a new way to estimate the ITE using…
Online adaptive radiation therapy (ART) has great promise to significantly reduce normal tissue toxicity and/or improve tumor control through real-time treatment adaptations based on the current patient anatomy. However, the major technical…
Magnetic Resonance Imaging (MRI) is a widely utilized diagnostic tool in clinical settings, but its application is limited by the relatively long acquisition time. As a result, fast MRI reconstruction has become a significant area of…
While medical imaging typically provides massive amounts of data, the extraction of relevant information for predictive diagnosis remains a difficult challenge. Functional MRI (fMRI) data, that provide an indirect measure of task-related or…
Background: In vivo dosimetry is essential for treatment verification in modern radiotherapy, but existing techniques are limited by spatiotemporal resolution and performance on non-uniform anatomy. Scintillation imaging dosimetry shows…