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Fluorescence microscopy is an essential tool for the analysis of 3D subcellular structures in tissue. An important step in the characterization of tissue involves nuclei segmentation. In this paper, a two-stage method for segmentation of…

图像与视频处理 · 电气工程与系统科学 2020-01-10 David Joon Ho , Shuo Han , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Advances in fluorescence microscopy enable acquisition of 3D image volumes with better image quality and deeper penetration into tissue. Segmentation is a required step to characterize and analyze biological structures in the images and…

计算机视觉与模式识别 · 计算机科学 2019-04-16 Chichen Fu , Soonam Lee , David Joon Ho , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Automatic segmentation of microscopy images is an important task in medical image processing and analysis. Nucleus detection is an important example of this task. Mask-RCNN is a recently proposed state-of-the-art algorithm for object…

计算机视觉与模式识别 · 计算机科学 2021-04-01 Jeremiah W. Johnson

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

图像与视频处理 · 电气工程与系统科学 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Object detection and classification is one of the most important computer vision problems. Ever since the introduction of deep learning \cite{krizhevsky2012imagenet}, we have witnessed a dramatic increase in the accuracy of this object…

计算机视觉与模式识别 · 计算机科学 2018-11-20 Gurjeet Singh , Sun Miao , Shi Shi , Patrick Chiang

Accurate assessment of Lung nodules is a time consuming and error prone ingredient of the radiologist interpretation work. Automating 3D volume detection and segmentation can improve workflow as well as patient care. Previous works have…

图像与视频处理 · 电气工程与系统科学 2019-07-29 Evi Kopelowitz , Guy Engelhard

As a fundamental part of computational healthcare, Computer Tomography (CT) and Magnetic Resonance Imaging (MRI) provide volumetric data, making the development of algorithms for 3D image analysis a necessity. Despite being computationally…

图像与视频处理 · 电气工程与系统科学 2023-07-26 C. I. Ugwu , S. Casarin , O. Lanz

Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

计算机视觉与模式识别 · 计算机科学 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Accurate detection and segmentation of cell nuclei in volumetric (3D) fluorescence microscopy datasets is an important step in many biomedical research projects. Although many automated methods for these tasks exist, they often struggle for…

计算机视觉与模式识别 · 计算机科学 2020-06-16 Martin Weigert , Uwe Schmidt , Robert Haase , Ko Sugawara , Gene Myers

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

计算机视觉与模式识别 · 计算机科学 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi

Microscopy imaging techniques are instrumental for characterization and analysis of biological structures. As these techniques typically render 3D visualization of cells by stacking 2D projections, issues such as out-of-plane excitation and…

图像与视频处理 · 电气工程与系统科学 2023-02-16 Amirkoushyar Ziabari , Derek C. Rose , Abbas Shirinifard , David Solecki

Segmentation of cell nuclei in microscopy images is a prevalent necessity in cell biology. Especially for three-dimensional datasets, manual segmentation is prohibitively time-consuming, motivating the need for automated methods.…

计算机视觉与模式识别 · 计算机科学 2020-02-10 Peter Hirsch , Dagmar Kainmueller

Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

计算机视觉与模式识别 · 计算机科学 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

计算机视觉与模式识别 · 计算机科学 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Tracking cells in 3D at high speed continues to attract extensive attention for many biomedical applications, such as monitoring immune cell migration and observing tumor metastasis in flowing blood vessels. Here, we propose a deep…

光学 · 物理学 2018-05-16 Kan Liu , Hui Qiao , Jiamin Wu , Haoqian Wang , Lu Fang , Qionghai Dai

3D landmark detection is a critical task in medical image analysis, and accurately detecting anatomical landmarks is essential for subsequent medical imaging tasks. However, mainstream deep learning methods in this field struggle to…

计算机视觉与模式识别 · 计算机科学 2025-10-22 Zhen Huang , Tao Tang , Ronghao Xu , Yangbo Wei , Wenkai Yang , Suhua Wang , Xiaoxin Sun , Han Li , Qingsong Yao

The rapid development in representation learning techniques such as deep neural networks and the availability of large-scale, well-annotated medical imaging datasets have to a rapid increase in the use of supervised machine learning in the…

计算机视觉与模式识别 · 计算机科学 2023-04-19 Dat T. Ngo , Thao T. B. Nguyen , Hieu T. Nguyen , Dung B. Nguyen , Ha Q. Nguyen , Hieu H. Pham

Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-related biomedical investigations. Due to their large scale in…

计算机视觉与模式识别 · 计算机科学 2018-08-15 Xiaoyuan Guo , Hanyi Yu , Blair Rossetti , George Teodoro , Daniel Brat , Jun Kong

In many applications of aerial/satellite image analysis (remote sensing), the generation of exact shapes of objects is a cumbersome task. In most remote sensing applications such as counting objects requires only location estimation of…

计算机视觉与模式识别 · 计算机科学 2021-12-14 N. Lakmal Deshapriya , Dan Tran , Sriram Reddy , Kavinda Gunasekara

The presented algorithms for segmentation and tracking follow a 3-step approach where we detect, track and finally segment nuclei. In the preprocessing phase, we detect centroids of the cell nuclei using a convolutional neural network (CNN)…

计算机视觉与模式识别 · 计算机科学 2019-04-16 Dennis Eschweiler , Johannes Stegmaier
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