中文
相关论文

相关论文: A Diffeomorphic Aging Model for Adult Human Brain …

200 篇论文

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

机器学习 · 计算机科学 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

We propose a method to predict the subject-specific longitudinal progression of brain structures extracted from baseline MRI, and evaluate its performance on Alzheimer's disease data. The disease progression is modeled as a trajectory on a…

计算机视觉与模式识别 · 计算机科学 2017-11-27 Alexandre Bône , Maxime Louis , Alexandre Routier , Jorge Samper , Michael Bacci , Benjamin Charlier , Olivier Colliot , Stanley Durrleman

The deviation between chronological age and biological age is a well-recognized biomarker associated with cognitive decline and neurodegeneration. Age-related and pathology-driven changes to brain structure are captured by various…

机器学习 · 计算机科学 2022-11-01 Saurabh Sihag , Gonzalo Mateos , Corey McMillan , Alejandro Ribeiro

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

图像与视频处理 · 电气工程与系统科学 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Understanding how decision making changes across the lifespan is a central challenge for neuroscience, yet research on cognitive aging has remained largely disconnected from the theoretical and computational advances that now shape modern…

神经元与认知 · 定量生物学 2026-03-04 Michael B. Ryan , Letizia Ye , Anne K. Churchland

Machine learning analysis of longitudinal neuroimaging data is typically based on supervised learning, which requires a large number of ground-truth labels to be informative. As ground-truth labels are often missing or expensive to obtain…

机器学习 · 计算机科学 2021-06-29 Qingyu Zhao , Zixuan Liu , Ehsan Adeli , Kilian M. Pohl

Shape modelling describes methods aimed at capturing the natural variability of shapes and commonly relies on probabilistic interpretations of dimensionality reduction techniques such as principal component analysis. Due to their…

计算机视觉与模式识别 · 计算机科学 2018-10-10 Yaël Balbastre , Mikael Brudfors , Kevin Bronik , John Ashburner

Deep learning algorithms for predicting neuroimaging data have shown considerable promise in various applications. Prior work has demonstrated that deep learning models that take advantage of the data's 3D structure can outperform standard…

图像与视频处理 · 电气工程与系统科学 2023-03-07 Yuda Bi , Anees Abrol , Zening Fu , Jiayu Chen , Jingyu Liu , Vince Calhoun

Understanding individual cortical development is essential for identifying deviations linked to neurodevelopmental disorders. However, current normative modelling frameworks struggle to capture fine-scale anatomical details due to their…

Normative modeling enables individualized characterization of structural brain deviations by evaluating subjects against a reference population rather than a group average. Most existing implementations treat brain regions independently and…

统计方法学 · 统计学 2026-05-19 J. T. Korley

Cardiovascular disease, the leading cause of death globally, is an age-related disease. Understanding the morphological and functional changes of the heart during ageing is a key scientific question, the answer to which will help us define…

图像与视频处理 · 电气工程与系统科学 2022-10-11 Mengyun Qiao , Berke Doga Basaran , Huaqi Qiu , Shuo Wang , Yi Guo , Yuanyuan Wang , Paul M. Matthews , Daniel Rueckert , Wenjia Bai

We present a stochastic model of population dynamics exploiting cross-sectional data in trend analysis and forecasts for groups and cohorts of a population. While sharing the convenient features of classic Markov models, it alleviates the…

应用统计 · 统计学 2017-06-20 Agnieszka Werpachowska , Roman Werpachowski

Bone age assessment gives us evidence to analyze the children growth status and the rejuvenation involved chronological and biological ages. All the previous works consider left-hand X-ray image of a child in their works. In this paper, we…

计算机视觉与模式识别 · 计算机科学 2019-01-30 Hai-Duong Nguyen , Soo-Hyung Kim

We introduce a probabilistic generative model for disentangling spatio-temporal disease trajectories from series of high-dimensional brain images. The model is based on spatio-temporal matrix factorization, where inference on the sources is…

机器学习 · 统计学 2019-10-11 Clement Abi Nader , Nicholas Ayache , Philippe Robert , Marco Lorenzi

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing \textit{brain age gap} characterized by an elevated brain age relative to the chronological age can reflect…

机器学习 · 计算机科学 2025-01-06 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

The determination of biological brain age is a crucial biomarker in the assessment of neurological disorders and understanding of the morphological changes that occur during aging. Various machine learning models have been proposed for…

图像与视频处理 · 电气工程与系统科学 2023-06-12 Mansoor Ahmed , Usama Sardar , Sarwan Ali , Shafiq Alam , Murray Patterson , Imdad Ullah Khan

Brain age estimation is clinically important as it can provide valuable information in the context of neurodegenerative diseases such as Alzheimer's. Population graphs, which include multimodal imaging information of the subjects along with…

Brain aging is a complex and dynamic process, leading to functional and structural changes in the brain. These changes could lead to the increased risk of neurodegenerative diseases and cognitive decline. Accurate brain-age estimation…

图像与视频处理 · 电气工程与系统科学 2024-12-30 Saadat Behzadi , Danial Sharifrazi , Roohallah Alizadehsani , Mojtaba Lotfaliany , Mohammadreza Mohebbi

Brain Age (BA) estimation via Deep Learning has become a strong and reliable bio-marker for brain health, but the black-box nature of Neural Networks does not easily allow insight into the features of brain ageing.We trained a ResNet model…

神经元与认知 · 定量生物学 2022-07-26 Daniel Taylor , Jonathan Shock , Deshendran Moodley , Jonathan Ipser , Matthias Treder