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Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

We introduce deep neural networks for the analysis of anatomical shapes that learn a low-dimensional shape representation from the given task, instead of relying on hand-engineered representations. Our framework is modular and consists of…

计算机视觉与模式识别 · 计算机科学 2020-10-05 Benjamin Gutierrez Becker , Ignacio Sarasua , Christian Wachinger

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

机器学习 · 计算机科学 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Segmentation of Multiple Sclerosis (MS) lesions in longitudinal brain MR scans is performed for monitoring the progression of MS lesions. We hypothesize that the spatio-temporal cues in longitudinal data can aid the segmentation algorithm.…

图像与视频处理 · 电气工程与系统科学 2020-09-29 Stefan Denner , Ashkan Khakzar , Moiz Sajid , Mahdi Saleh , Ziga Spiclin , Seong Tae Kim , Nassir Navab

Normative modelling is an increasingly common statistical technique in neuroimaging that estimates population-level benchmarks in brain structure. It enables the quantification of individual deviations from expected distributions whilst…

神经元与认知 · 定量生物学 2025-10-21 Nida Alyas , Jonathan Horsley , Bethany Little , Peter N. Taylor , Yujiang Wang , Karoline Leiberg

Estimating brain age from structural MRI has emerged as a powerful tool for characterizing normative and pathological aging. In this work, we explore contrastive learning as a scalable and robust alternative to L1-supervised approaches for…

图像与视频处理 · 电气工程与系统科学 2025-12-09 Carlo Alberto Barbano , Benoit Dufumier , Edouard Duchesnay , Marco Grangetto , Pietro Gori

Brain age prediction based on neuroimaging data could help characterize both the typical brain development and neuropsychiatric disorders. Pattern recognition models built upon functional connectivity (FC) measures derived from resting…

计算机视觉与模式识别 · 计算机科学 2018-01-15 Hongming Li , Theodore D. Satterthwaite , Yong Fan

Brain lesions are abnormalities or injuries in brain tissue that are often detectable using magnetic resonance imaging (MRI), which reveals structural changes in the affected areas. This broad definition of brain lesions includes areas of…

计算机视觉与模式识别 · 计算机科学 2025-07-09 Omar Zamzam , Haleh Akrami , Anand Joshi , Richard Leahy

The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

定量方法 · 定量生物学 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg

Purpose: To develop an age prediction model which is interpretable and robust to demographic and technological variances in brain MRI scans. Materials and Methods: We propose a transformer-based architecture that leverages self-supervised…

计算机视觉与模式识别 · 计算机科学 2025-06-24 Pengyu Kan , Craig Jones , Kenichi Oishi

For constructing neuronal network models computational neuroscientists have access to wide-ranging anatomical data that nevertheless tend to cover only a fraction of the parameters to be determined. Finding and interpreting the most…

Investigation of age-related genes is of great importance for multiple purposes, for instance, improving our understanding of the mechanism of ageing, increasing life expectancy, age prediction, and other healthcare applications. In his…

基因组学 · 定量生物学 2021-11-05 Salman Mohamadi , Donald Adjeroh

The utilization of longitudinal datasets for glaucoma progression prediction offers a compelling approach to support early therapeutic interventions. Predominant methodologies in this domain have primarily focused on the direct prediction…

计算机视觉与模式识别 · 计算机科学 2024-11-06 Zhihao Zhao , Junjie Yang , Shahrooz Faghihroohi , Yinzheng Zhao , Daniel Zapp , Kai Huang , Nassir Navab , M. Ali Nasseri

MRI-based brain age estimation models aim to assess a subject's biological brain age based on information, such as neuroanatomical features. Various factors, including neurodegenerative diseases, can accelerate brain aging and measuring…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Simon Joseph Clément Crête , Marta Kersten-Oertel , Yiming Xiao

The brain's biological age has been considered as a promising candidate for a neurologically significant biomarker. However, recent results based on longitudinal magnetic resonance imaging data have raised questions on its interpretation. A…

神经元与认知 · 定量生物学 2023-10-12 Lukas AW Gemein , Robin T Schirrmeister , Joschka Boedecker , Tonio Ball

Deep learning techniques have demonstrated great potential for accurately estimating brain age by analyzing Magnetic Resonance Imaging (MRI) data from healthy individuals. However, current methods for brain age estimation often directly…

计算机视觉与模式识别 · 计算机科学 2024-09-24 Fanzhe Yan , Gang Yang , Yu Li , Aiping Liu , Xun Chen

Brain age prediction serves as a powerful framework for assessing brain status and detecting deviations associated with neurodevelopmental and neurodegenerative disorders. However, most existing approaches emphasize whole-brain age…

神经元与认知 · 定量生物学 2026-02-10 Rongzhao He , Dalin Zhu , Ying Wang , Songhong Yue , Leilei Zhao , Yu Fu , Dan Wu , Bin Hu , Weihao Zheng

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

计算机视觉与模式识别 · 计算机科学 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner