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The automatic detection of White Blood Cells (WBC) still remains as an unsolved issue in medical imaging. The analysis of WBC images has engaged researchers from fields of medicine and computer vision alike. Since WBC can be approximated by…

计算机视觉与模式识别 · 计算机科学 2014-06-30 Erik Cuevas , Margarita Diaz , Miguel Manzanares , Daniel Zaldivar , Marco Perez

A novel and fast semi-automatic method for segmentation, locating and counting blood cells in an image is proposed. In this method, thresholding is used to separate the nucleus from the other parts. We also use Hough transform for circles…

图像与视频处理 · 电气工程与系统科学 2020-04-21 Hamed Sadeghi , Shahram Shirani , David W. Capson

Human blood primarily comprises plasma, red blood cells, white blood cells, and platelets. It plays a vital role in transporting nutrients to different organs, where it stores essential health-related data about the human body. Blood cells…

图像与视频处理 · 电气工程与系统科学 2024-10-08 Rabia Asghar , Sanjay Kumar , Paul Hynds , Abeera Mahfooz

Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the…

Circulating blood cell clusters (CCCs) containing red blood cells (RBCs), white blood cells(WBCs), and platelets are significant biomarkers linked to conditions like thrombosis, infection, and inflammation. Flow cytometry, paired with…

计算机视觉与模式识别 · 计算机科学 2025-10-21 Suqiang Ma , Subhadeep Sengupta , Yao Lee , Beikang Gu , Xianyan Chen , Xianqiao Wang , Yang Liu , Mengjia Xu , Galit H. Frydman , He Li

White blood cells (WBC) are important parts of our immune system, and they protect our body against infections by eliminating viruses, bacteria, parasites and fungi. The number of WBC types and the total number of WBCs provide important…

计算机视觉与模式识别 · 计算机科学 2026-03-05 Sibasish Dhibar

White blood cell (WBC) classification is fundamental for hematology applications such as infection assessment, leukemia screening, and treatment monitoring. However, real-world WBC datasets present substantial appearance variations caused…

计算机视觉与模式识别 · 计算机科学 2026-03-03 Luu Le , Hoang-Loc Cao , Ha-Hieu Pham , Thanh-Huy Nguyen , Ulas Bagci

Automated white blood cell (WBC) classification is essential for leukemia screening but remains challenged by extreme class imbalance, long-tail distributions, and domain shift, leading deep models to overfit dominant classes and fail on…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Duc T. Nguyen , Hoang-Long Nguyen , Huy-Hieu Pham

Accurate skin disease classification is a critical yet challenging task due to high inter-class similarity, intra-class variability, and complex lesion textures. While deep learning-based computer-aided diagnosis (CAD) systems have shown…

计算机视觉与模式识别 · 计算机科学 2025-08-07 Enam Ahmed Taufik , Abdullah Khondoker , Antara Firoz Parsa , Seraj Al Mahmud Mostafa

The classification of white blood cells (WBCs) from peripheral blood smears is critical for the diagnosis of leukemia. However, automated approaches still struggle due to challenges including class imbalance, domain shift, and morphological…

计算机视觉与模式识别 · 计算机科学 2026-03-24 Antony Gitau , Martin Paulson , Bjørn-Jostein Singstad , Karl Thomas Hjelmervik , Ola Marius Lysaker , Veralia Gabriela Sanchez

Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…

计算机视觉与模式识别 · 计算机科学 2023-11-27 Stefan Röhrl , Johannes Groll , Manuel Lengl , Simon Schumann , Christian Klenk , Dominik Heim , Martin Knopp , Oliver Hayden , Klaus Diepold

Red blood cells are highly deformable and present in various shapes. In blood cell disorders, only a subset of all cells is morphologically altered and relevant for the diagnosis. However, manually labeling of all cells is laborious,…

计算机视觉与模式识别 · 计算机科学 2020-07-24 Ario Sadafi , Asya Makhro , Anna Bogdanova , Nassir Navab , Tingying Peng , Shadi Albarqouni , Carsten Marr

Cell image classification methods are currently being used in numerous applications in cell biology and medicine. Applications include understanding the effects of genes and drugs in screening experiments, understanding the role and…

定量方法 · 定量生物学 2022-03-04 Mohammad Shifat-E-Rabbi , Xuwang Yin , Cailey Elizabeth Fitzgerald , Gustavo K. Rohde

Automated red blood cell (RBC) classification on blood smear images helps hematologists to analyze RBC lab results in a reduced time and cost. However, overlapping cells can cause incorrect predicted results, and so they have to be…

图像与视频处理 · 电气工程与系统科学 2024-10-30 Korranat Naruenatthanaset , Thanarat H. Chalidabhongse , Duangdao Palasuwan , Nantheera Anantrasirichai , Attakorn Palasuwan

Cell detection and cell type classification from biomedical images play an important role for high-throughput imaging and various clinical application. While classification of single cell sample can be performed with standard computer…

图像与视频处理 · 电气工程与系统科学 2019-12-17 Wei Qiu , Jiaming Guo , Xiang Li , Mengjia Xu , Mo Zhang , Ning Guo , Quanzheng Li

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

计算机视觉与模式识别 · 计算机科学 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Diagnosing hematological malignancies requires identification and classification of white blood cells in peripheral blood smears. Domain shifts caused by different lab procedures, staining, illumination, and microscope settings hamper the…

计算机视觉与模式识别 · 计算机科学 2022-07-04 Raheleh Salehi , Ario Sadafi , Armin Gruber , Peter Lienemann , Nassir Navab , Shadi Albarqouni , Carsten Marr

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

图像与视频处理 · 电气工程与系统科学 2024-03-01 Ha Anh Vu

Digital pathology has recently been revolutionized by advancements in artificial intelligence, deep learning, and high-performance computing. With its advanced tools, digital pathology can help improve and speed up the diagnostic process,…

图像与视频处理 · 电气工程与系统科学 2024-03-28 Mohamed Elmanna , Ahmed Elsafty , Yomna Ahmed , Muhammad Rushdi , Ahmed Morsy

White blood cells, also known as leukocytes are group of heterogeneously nucleated cells which act as salient immune system cells. These are originated in the bone marrow and are found in blood, plasma, and lymph tissues. Leukocytes kill…

图像与视频处理 · 电气工程与系统科学 2023-12-01 Shrijeet Biswas , Amartya Bhattacharya