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Deciphering the control principles of metabolism and its interaction with other cellular functions is central to biomedicine and biotechnology. Yet, understanding the efficient control of metabolic fluxes remains elusive for large-scale…

分子网络 · 定量生物学 2015-09-04 Georg Basler , Zoran Nikoloski , Abdelhalim Larhlimi , Albert-László Barabási , Yang-Yu Liu

In this paper, we consider a molecular diffusion based communications link that can reliably transport data over-the-air. We show that the system can also reliably transport data across confined structural environments, especially in cases…

新兴技术 · 计算机科学 2014-03-28 Song Qiu , Weisi Guo , Siyi Wang , Nariman Farsad , Andrew Eckford

The existence of fully transmissive eigenchannels ("open channels") in a random scattering medium is a counterintuitive and unresolved prediction of random matrix theory. The smoking gun of such open channels, namely a bimodal distribution…

The macroscopic behavior of the solution of a coupled system of partial differential equations arising in the modeling of reaction-diffusion processes in periodic porous media is analyzed. Our mathematical model can be used for studying…

偏微分方程分析 · 数学 2019-06-19 G. Cardone , C. Perugia , C. Timofte

We develop a mesoscopic modeling framework for diffusion in a crowded environment, particularly targeting applications in the modeling of living cells. Through homogenization techniques we effectively coarse-grain a detailed microscopic…

亚细胞过程 · 定量生物学 2018-09-19 Stefan Engblom , Per Lötstedt , Lina Meinecke

This work presents a performance analysis for diffusive molecular communication with mobile transmit and receive nanomachines. To begin with, the optimal test is obtained for symbol detection at the receiver nanomachine. Subsequently,…

信息论 · 计算机科学 2017-10-04 Neeraj Varshney , Aditya K. Jagannatham , Pramod K. Varshney

Scattering is an important phenomenon which is observed in systems ranging from the micro- to macroscale. In the context of nuclear reaction theory the Heidelberg approach was proposed and later demonstrated to be applicable to many chaotic…

The study of the ability of drug molecules to enter cells through the membrane is of vital importance in the field of drug delivery. In cases where the transport of the drug molecules through the membrane is not easily accomplishable, other…

软凝聚态物质 · 物理学 2015-03-17 Sridhar Akshay , Bharath Srikanth , Amit Kumar , Ashok Kumar Dasmahapatra

Drug-loaded hydrogels provide a means to deliver pharmaceutical agents to specific sites within the body at a controlled rate. The aim of this paper is to understand how controlled drug release can be achieved by tuning the initial…

最优化与控制 · 数学 2022-02-07 Matthew J. Penn , Matthew G. Hennessy

Due to the limited capabilities of a single bio-nanomachine, complicated tasks can be performed only with the co-operation of multiple bio-nanomachines. In this work, we consider a diffusion-based molecular communication system with a…

信息论 · 计算机科学 2020-05-20 Nithin V. Sabu , Abhishek K. Gupta

In this paper, we propose a novel concept for engineered molecular communication (MC) systems inspired by animal olfaction. We focus on a multi-user scenario where several transmitters wish to communicate with a central receiver. We assume…

信息论 · 计算机科学 2022-03-09 Vahid Jamali , Helene M. Loos , Andrea Buettner , Robert Schober , H. Vincent Poor

In molecular communications, the direct detection of signaling molecules may be challenging due to a lack of suitable sensors and interference in the environment. Motivated by research in molecular biology, we investigate an indirect…

We consider the classical problem of particle diffusion in $d$-dimensional radially-symmetric systems with absorbing boundaries. A key quantity to characterise such diffusive transport is the evolution of the proportion of particles…

计算物理 · 物理学 2022-09-07 Elliot J. Carr

The dynamics of a tracer particle in a glassy matrix of obstacles displays slow complex transport as the free volume approaches a critical value and the void space falls apart. We investigate the emerging subdiffusive motion of the test…

The motion of molecules across channels is critically important for understanding mechanisms of cellular processes. Here we investigate the mechanism of interactions in the molecular transport by analyzing exactly solvable discrete…

软凝聚态物质 · 物理学 2015-05-18 Anatoly B. Kolomeisky , Karthik Uppulury

In this paper, we propose a molecular communication system to localize an abnormality in a diffusion based medium. We consider a general setup to perform joint sensing, communication and localization. This setup consists of three types of…

信号处理 · 电气工程与系统科学 2022-04-01 Ladan Khaloopour , Mahtab Mirmohseni , Masoumeh Nasiri-Kenari

Design and characterisation of capsules is not an easy task owing to the multiple involved preparation factors and parameters. Here, a novel method to characterise capsule membrane permeability to solute molecules by an inverse approach is…

医学物理 · 物理学 2021-11-03 Clément Bielinski , Badr Kaoui

Chemical reactions inside cells are generally considered to happen within fixed-size compartments. Needless to say, cells and their compartments are highly dynamic. Thus, such stringent assumptions may not reflect biochemical reality, and…

定量方法 · 定量生物学 2016-02-17 Atiyo Ghosh , Tatiana T. Marquez-Lago

From nutrient uptake, to chemoreception, to synaptic transmission, many systems in cell biology depend on molecules diffusing and binding to membrane receptors. Mathematical analysis of such systems often neglects the fact that receptors…

定量方法 · 定量生物学 2021-06-16 Gregory Handy , Sean D Lawley

How many times a diffusing molecule can permeate across a membrane or be adsorbed on a substrate? We employ the encounter-based approach to find the statistics of adsorption or permeation events for molecular diffusion in a general…

化学物理 · 物理学 2025-07-15 Denis S. Grebenkov