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The use of causal mediation analysis to evaluate the pathways by which an exposure affects an outcome is widespread in the social and biomedical sciences. Recent advances in this area have established formal conditions for identification…

统计方法学 · 统计学 2018-08-14 Isabel R. Fulcher , Xu Shi , Eric J. Tchetgen Tchetgen

Causal discovery is crucial for understanding complex systems and informing decisions. While observational data can uncover causal relationships under certain assumptions, it often falls short, making active interventions necessary. Current…

机器学习 · 计算机科学 2024-06-18 Yuxuan Wang , Mingzhou Liu , Xinwei Sun , Wei Wang , Yizhou Wang

Interventions are of fundamental importance in Pearl's probabilistic causality regime. In this paper, we will inspect how interventions influence the interpretation of causation in causal models in specific situation. To this end, we will…

人工智能 · 计算机科学 2020-03-27 Mehrzad Saremi

Recent approaches to empathetic response generation incorporate emotion causalities to enhance comprehension of both the user's feelings and experiences. However, these approaches suffer from two critical issues. First, they only consider…

计算与语言 · 计算机科学 2024-04-09 Jiashuo Wang , Yi Cheng , Wenjie Li

Theoretical studies on chemical reaction mechanisms have been crucial in organic chemistry. Traditionally, calculating the manually constructed molecular conformations of transition states for chemical reactions using quantum chemical…

化学物理 · 物理学 2024-04-12 Sihao Yuan , Xu Han , Jun Zhang , Zhaoxin Xie , Cheng Fan , Yunlong Xiao , Yi Qin Gao , Yi Isaac Yang

Deep neural networks are increasingly utilized in mobility prediction tasks, yet their intricate internal workings pose challenges for interpretability, especially in comprehending how various aspects of mobility behavior affect…

物理与社会 · 物理学 2024-08-02 Ye Hong , Yanan Xin , Simon Dirmeier , Fernando Perez-Cruz , Martin Raubal

In this paper we present a data-adaptive estimation procedure for estimation of average treatment effects in a time-to-event setting based on generalized random forests. In these kinds of settings, the definition of causal effect parameters…

统计方法学 · 统计学 2021-04-28 Helene C. W. Rytgaard , Claus T. Ekstrøm , Lars V. Kessing , Thomas A. Gerds

Modern machine learning (ML) methods typically fail to adequately capture causal information. Consequently, such models do not handle data distributional shifts, are vulnerable to adversarial examples, and often learn spurious correlations.…

量子物理 · 物理学 2026-01-27 Rishi Goel , Casey R. Myers , Sally Shrapnel

Selection bias is a major obstacle toward valid causal inference in epidemiology. Over the past decade, several graphical rules based on causal diagrams have been proposed as the sufficient identification conditions for addressing selection…

统计方法学 · 统计学 2025-12-18 Yichi Zhang , Haidong Lu

Recently, there has been extensive research on the capabilities of biologically plausible algorithms. In this work, we show how one of such algorithms, called predictive coding, is able to perform causal inference tasks. First, we show how…

机器学习 · 计算机科学 2024-06-04 Tommaso Salvatori , Luca Pinchetti , Amine M'Charrak , Beren Millidge , Thomas Lukasiewicz

The incorporation of causal inference in mediation analysis has led to theoretical and methodological advancements -- effect definitions with causal interpretation, clarification of assumptions required for effect identification, and an…

统计方法学 · 统计学 2022-10-31 Trang Quynh Nguyen , Ian Schmid , Elizabeth A. Stuart

Mediation analysis is concerned with the decomposition of the total effect of an exposure on an outcome into the indirect effect through a given mediator, and the remaining direct effect. This is ideally done using longitudinal measurements…

统计理论 · 数学 2019-12-04 Murthy N Mittinty , Stijn Vansteelandt

Mediation analysis is difficult when the number of potential mediators is larger than the sample size. In this paper we propose new inference procedures for the indirect effect in the presence of high-dimensional mediators for linear…

统计方法学 · 统计学 2019-10-29 Ruixuan Rachel Zhou , Liewei Wang , Sihai Dave Zhao

Estimating individual-level treatment effect from observational data is a fundamental problem in causal inference and has attracted increasing attention in the fields of education, healthcare, and public policy.In this work, we concentrate…

机器学习 · 计算机科学 2025-07-10 Hui Meng , Keping Yang , Xuyu Peng , Bo Zheng

Mediation analysis is a crucial tool for uncovering the mechanisms through which a treatment affects the outcome, providing deeper causal insights and guiding effective interventions. Despite advances in analyzing the mediation effect with…

统计方法学 · 统计学 2025-08-11 Shi Bo , AmirEmad Ghassami , Debarghya Mukherjee

There exist well-developed frameworks for causal modelling, but these require rather a lot of human domain expertise to define causal variables and perform interventions. In order to enable autonomous agents to learn abstract causal models…

人工智能 · 计算机科学 2022-08-15 Taco Cohen

Disentangling the mechanistic details of a chemical reaction pathway is a hard problem that often requires a considerable amount of chemical intuition and a component of luck. Experiments struggle in observing short-life metastable…

化学物理 · 物理学 2019-08-01 Valerio Rizzi , Dan Mendels , Emilia Sicilia , Michele Parrinello

We propose causal effect estimators based on empirical Fr\'{e}chet means and operator-valued kernels, tailored to functional data spaces. These methods address the challenges of high-dimensionality, sequential ordering, and model complexity…

统计方法学 · 统计学 2025-06-04 Yordan P. Raykov , Hengrui Luo , Justin D. Strait , Wasiur R. KhudaBukhsh

Causal representation learning (CRL) enhances machine learning models' robustness and generalizability by learning structural causal models associated with data-generating processes. We focus on a family of CRL methods that uses contrastive…

机器学习 · 统计学 2025-03-17 Xiusi Li , Sékou-Oumar Kaba , Siamak Ravanbakhsh

Natural experiments are a cornerstone of applied economics, providing settings for estimating causal effects with a compelling argument for treatment randomisation, but give little indication of the mechanisms behind causal effects. Causal…

计量经济学 · 经济学 2025-10-07 Senan Hogan-Hennessy