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Oblique plane microscopy (OPM) enables high speed, volumetric fluorescence imaging through a single-objective geometry. While these advantages have positioned OPM as a valuable tool to probe biological questions in animal models, its…
Circular dichroism is the differential rate of absorption of right- and left-handed circularly polarized light by chiral particles. Optical vortices which convey orbital angular momentum (OAM) possess a chirality associated with the…
Recently developed methods for rapid continuous volumetric two-photon microscopy facilitate the observation of neuronal activity in hundreds of individual neurons and changes in blood flow in adjacent blood vessels across a large volume of…
Optical coherence tomography (OCT) is capable of non-destructively obtaining cross-sectional information of samples with micrometer spatial resolution, which plays an important role in ophthalmology and endovascular medicine. Measuring OCT…
Holographic coherent X-ray imaging enables nanoscale imaging of biological cells and tissues, rendering both phase and absorption contrast, i.e. real and imaginary parts of the refractive index. Unlike the standard model, which assumes a…
Medical ultrasound (US) is widely used to evaluate and stage vascular diseases, in particular for the preliminary screening program, due to the advantage of being radiation-free. However, automatic segmentation of small tubular structures…
Optical coherence tomography (OCT) uses low-coherence reflectometry to obtain cross-sectional images of inhomogeneous media, such as biological tissue. OCT is particularly useful in the biomedical ea, since the imaging can be performed…
Shape graphs are complex geometrical structures commonly found in biological and anatomical systems. A shape graph is a collection of nodes, some connected by curvilinear edges with arbitrary shapes. Their high complexity stems from the…
Nuclei of ordered materials emerging from the isotropic state usually show a shape topologically equivalent to a sphere; the well-known examples are crystals and nematic liquid crystal droplets. In this work, we explore experimentally and…
The cornea, as the outer element of the human eye, plays a pivotal role in vision. Any defects in its shape can result in visual impairments. Mechanical defect manifest as shape defects, as the cornea is under to pressure. Our study…
With development of information technology and necessity for high security, using different identification methods has become very important. Each biometric feature has its own advantages and disadvantages and choosing each of them depends…
Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…
Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using…
Periocular refers to the facial region in the vicinity of the eye, including eyelids, lashes and eyebrows. While face and irises have been extensively studied, the periocular region has emerged as a promising trait for unconstrained…
Segmenting the retinal vasculature entails a trade-off between how much of the overall vascular structure we identify vs. how precisely we segment individual vessels. In particular, state-of-the-art methods tend to under-segment faint…
Advanced atherosclerosis in the coronary arteries is one of the leading causes of deaths worldwide while being preventable and treatable. In order to image atherosclerotic lesions (plaque), intravascular optical coherence tomography (IVOCT)…
Optical Coherence Tomography (OCT) has become an indispensable tool for investigating mesoscopic features in soft matter and fluid mechanics. Its ability to provide high-resolution, non-invasive measurements in both spatial and temporal…
State-of-the-art coronagraphs employed on extreme adaptive optics enabled instruments, are constantly improving the contrast detection limit for companions at ever closer separations to the host star. In order to constrain their properties…
Based on diffraction theory and the propagation of the light, Fourier optics is a powerful tool allowing the estimation of a visible-range imaging system to transfer the spatial frequency components of an object. The analyses of the imaging…
The precise delineation of blood vessels in medical images is critical for many clinical applications, including pathology detection and surgical planning. However, fully-automated vascular segmentation is challenging because of the…