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Inferring how an epidemic will progress and what actions to take when presented with limited information is of critical importance for epidemiologists and health professionals. In real world settings, epidemiology data can be scarce or…

统计计算 · 统计学 2022-11-02 Georgios Efstathiadis

We show how Markov mixed membership models (MMMM) can be used to predict the degradation of assets. We model the degradation path of individual assets, to predict overall failure rates. Instead of a separate distribution for each hidden…

机器学习 · 计算机科学 2020-06-03 Paul Hofmann , Zaid Tashman

In machine learning and statistics, probabilistic inference involving multimodal distributions is quite difficult. This is especially true in high dimensional problems, where most existing algorithms cannot easily move from one mode to…

统计计算 · 统计学 2015-06-22 Shiwei Lan , Jeffrey Streets , Babak Shahbaba

Markov state models (MSMs) have been demonstrated to be a powerful method for computationally studying intramolecular processes such as protein folding and macromolecular conformational changes. In this article, we present a new approach to…

生物物理 · 物理学 2015-06-18 Matthew R. Perkett , Michael F. Hagan

Markov chain Monte Carlo is a class of algorithms for drawing Markovian samples from high-dimensional target densities to approximate the numerical integration associated with computing statistical expectation, especially in Bayesian…

统计计算 · 统计学 2018-03-28 Khoa T. Tran

Agent-based model (ABM) has been widely used to study infectious disease transmission by simulating behaviors and interactions of autonomous individuals called agents. In the ABM, agent states, for example infected or susceptible, are…

应用统计 · 统计学 2022-12-09 Seungha Um , Samrachana Adhikari

For large model spaces, the potential entrapment of Markov chain Monte Carlo (MCMC) based methods with spike-and-slab priors poses significant challenges in posterior computation in regression models. On the other hand, maximum a posteriori…

统计方法学 · 统计学 2026-02-25 Shamriddha De , Joyee Ghosh

Recent developments in differentially private (DP) machine learning and DP Bayesian learning have enabled learning under strong privacy guarantees for the training data subjects. In this paper, we further extend the applicability of DP…

机器学习 · 统计学 2019-06-18 Mikko A. Heikkilä , Joonas Jälkö , Onur Dikmen , Antti Honkela

We develop a novel advanced Particle Markov chain Monte Carlo algorithm that is capable of sampling from the posterior distribution of non-linear state space models for both the unobserved latent states and the unknown model parameters. We…

统计方法学 · 统计学 2015-03-17 Gareth W. Peters , Geoff R. Hosack , Keith R. Hayes

Factorial Hidden Markov Models (FHMMs) are powerful models for sequential data but they do not scale well with long sequences. We propose a scalable inference and learning algorithm for FHMMs that draws on ideas from the stochastic…

机器学习 · 统计学 2016-10-31 Yin Cheng Ng , Pawel Chilinski , Ricardo Silva

The main aim to build models capable of simulating the spreading of infectious diseases is to control them. And along this way, the key to find the optimal strategy for disease control is to obtain a large number of simulations of disease…

社会与信息网络 · 计算机科学 2022-04-22 Ting Wang , Gui-Yun Li , Xin-Hui Li , Chi-Chun Zhou , Yuan-Yuan Wang , Li-Juan Li , Yan-Ting Yang

In this paper, we address technical difficulties that arise when applying Markov chain Monte Carlo (MCMC) to hierarchical models designed to perform clustering in the space of latent parameters of subject-wise generative models.…

定量方法 · 定量生物学 2020-12-15 Yu Yao , Klaas E. Stephan

Motivated by examples from genetic association studies, this paper considers the model selection problem in a general complex linear model system and in a Bayesian framework. We discuss formulating model selection problems and incorporating…

统计方法学 · 统计学 2014-03-14 Xiaoquan Wen

Varying coefficient models (VCMs) are widely used for estimating nonlinear regression functions for functional data. Their Bayesian variants using Gaussian process priors on the functional coefficients, however, have received limited…

统计方法学 · 统计学 2022-03-01 Rajarshi Guhaniyogi , Cheng Li , Terrance D. Savitsky , Sanvesh Srivastava

We develop a modular approach to Markov chain Monte Carlo (MCMC) sampling for unnormalized target densities. In this approach, Markov chains are constructed in parallel, each constrained to a subset of the target space. The Monte Carlo…

统计计算 · 统计学 2026-05-05 Joonha Park

This paper explores the versatility and depth of Bayesian modeling by presenting a comprehensive range of applications and methods, combining Markov chain Monte Carlo (MCMC) techniques and variational approximations. Covering topics such as…

应用统计 · 统计学 2025-02-18 Yifei Yan , Juan Sosa , Carlos A. Martínez

Cycles are fundamental to human health and behavior. However, modeling cycles in time series data is challenging because in most cases the cycles are not labeled or directly observed and need to be inferred from multidimensional…

社会与信息网络 · 计算机科学 2018-04-23 Emma Pierson , Tim Althoff , Jure Leskovec

Due to the escalating growth of big data sets in recent years, new Bayesian Markov chain Monte Carlo (MCMC) parallel computing methods have been developed. These methods partition large data sets by observations into subsets. However, for…

统计方法学 · 统计学 2019-01-21 Zheng Wei , Erin M. Conlon

Emerging infectious diseases and climate change are two of the major challenges in 21st century. Although over the past decades, highly-resolved mathematical models have contributed in understanding dynamics of infectious diseases and are…

种群与进化 · 定量生物学 2025-10-13 Julia Bicker , René Schmieding , Michael Meyer-Hermann , Martin J. Kühn

Importance sampling (IS) is commonly used for cross validation (CV) in Bayesian models, because it only involves reweighting existing posterior draws without needing to re-estimate the model by re-running Markov chain Monte Carlo (MCMC).…

统计计算 · 统计学 2025-08-12 Geonhee Han , Andrew Gelman
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