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Empirical research in the social and medical sciences frequently involves testing multiple hypotheses simultaneously, increasing the risk of false positives due to chance. Classical multiple testing procedures, such as the Bonferroni…

计量经济学 · 经济学 2025-07-29 Sebastian Calonico , Sebastian Galiani

We propose a method for testing whether hierarchically ordered groups of potentially correlated variables are significant for explaining a response in a high-dimensional linear model. In presence of highly correlated variables, as is very…

统计理论 · 数学 2014-09-04 Jacopo Mandozzi , Peter Bühlmann

High-dimensional group inference is an essential part of statistical methods for analysing complex data sets, including hierarchical testing, tests of interaction, detection of heterogeneous treatment effects and inference for local…

统计方法学 · 统计学 2020-12-01 Zijian Guo , Claude Renaux , Peter Bühlmann , T. Tony Cai

In complex clinical trials, multiple research objectives are often grouped into sets of objectives based on their inherent hierarchical relationships. Consequently, the hypotheses formulated to address these objectives are grouped into…

统计方法学 · 统计学 2016-11-11 Zhiying Qiu , Wenge Guo , Sanat Sarkar

Hierarchical models represent a challenging setting for inference algorithms. MCMC methods struggle to scale to large models with many local variables and observations, and variational inference (VI) may fail to provide accurate…

机器学习 · 计算机科学 2022-07-27 Tomas Geffner , Justin Domke

We propose a general, modular method for significance testing of groups (or clusters) of variables in a high-dimensional linear model. In presence of high correlations among the covariables, due to serious problems of identifiability, it is…

统计理论 · 数学 2015-02-12 Jacopo Mandozzi , Peter Bühlmann

Adjustment of statistical significance levels for repeated analysis in group sequential trials has been understood for some time. Similarly, methods for adjustment accounting for testing multiple hypotheses are common. There is limited…

统计方法学 · 统计学 2023-11-28 Yujie Zhao , Qi Liu , Linda Z. Sun , Keaven M. Anderson

This paper tackles the challenge of performing multiple quantile regressions across different quantile levels and the associated problem of controlling the familywise error rate, an issue that is generally overlooked in practice. We propose…

统计方法学 · 统计学 2026-04-10 Riccardo De Santis , Anna Vesely , Angela Andreella

For many practical problems, the regression models follow the strong heredity property (also known as the marginality), which means they include parent main effects when a second-order effect is present. Existing methods rely mostly on…

统计方法学 · 统计学 2020-07-28 Kedong Chen , William Li , Sijian Wang

Current statistical inference problems in areas like astronomy, genomics, and marketing routinely involve the simultaneous testing of thousands -- even millions -- of null hypotheses. For high-dimensional multivariate distributions, these…

统计方法学 · 统计学 2017-04-25 Weixin Cai , Nima S. Hejazi , Alan E. Hubbard

In many large multiple testing problems the hypotheses are divided into families. Given the data, families with evidence for true discoveries are selected, and hypotheses within them are tested. Neither controlling the error-rate in each…

统计理论 · 数学 2011-06-21 Yoav Benjamini , Marina Bogomolov

During multiple testing, researchers often adjust their alpha level to control the familywise error rate for a statistical inference about a joint union alternative hypothesis (e.g., "H1,1 or H1,2"). However, in some cases, they do not make…

统计方法学 · 统计学 2024-04-04 Mark Rubin

Multi-label classification is a common challenge in various machine learning applications, where a single data instance can be associated with multiple classes simultaneously. The current paper proposes a novel tree-based method for…

统计方法学 · 统计学 2024-05-01 Chhavi Tyagi , Wenge Guo

Bonferroni's correction is a popular tool to address multiplicity but is notorious for its low power when tests are dependent. This paper proposes a practical modification of Bonferroni's correction when test statistics are jointly normal…

统计方法学 · 统计学 2026-02-24 Caleb Hiltunen , Yeonwoo Rho

Hierarchical forecasting is a key problem in many practical multivariate forecasting applications - the goal is to simultaneously predict a large number of correlated time series that are arranged in a pre-specified aggregation hierarchy.…

机器学习 · 计算机科学 2021-10-13 Biswajit Paria , Rajat Sen , Amr Ahmed , Abhimanyu Das

High-dimensional vector autoregression with measurement error is frequently encountered in a large variety of scientific and business applications. In this article, we study statistical inference of the transition matrix under this model.…

统计方法学 · 统计学 2020-09-18 Xiang Lyu , Jian Kang , Lexin Li

Hierarchical models are versatile tools for joint modeling of data sets arising from different, but related, sources. Fully Bayesian inference may, however, become computationally prohibitive if the source-specific data models are complex,…

统计计算 · 统计学 2016-05-06 Ritabrata Dutta , Paul Blomstedt , Samuel Kaski

We analyze control of the familywise error rate (FWER) in a multiple testing scenario with a great many null hypotheses about the distribution of a high-dimensional random variable among which only a very small fraction are false, or…

统计方法学 · 统计学 2015-09-15 Kamel Lahouel , Donald Geman , Laurent Younes

Cluster analysis has proved to be an invaluable tool for the exploratory and unsupervised analysis of high dimensional datasets. Among methods for clustering, hierarchical approaches have enjoyed substantial popularity in genomics and other…

统计方法学 · 统计学 2014-11-20 Patrick K. Kimes , Yufeng Liu , D. Neil Hayes , J. S. Marron

Hierarchical categorical variables often exhibit many levels (high granularity) and many classes within each level (high dimensionality). This may cause overfitting and estimation issues when including such covariates in a predictive model.…

统计方法学 · 统计学 2024-08-20 Paul Wilsens , Katrien Antonio , Gerda Claeskens
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