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The brain must extract behaviorally relevant latent variables from the signals streamed by the sensory organs. Such latent variables are often encoded in the dynamics that generated the signal rather than in the specific realization of the…

神经元与认知 · 定量生物学 2021-10-07 Tiberiu Tesileanu , Siavash Golkar , Samaneh Nasiri , Anirvan M. Sengupta , Dmitri B. Chklovskii

Learning interpretable representations of neural dynamics at a population level is a crucial first step to understanding how observed neural activity relates to perception and behavior. Models of neural dynamics often focus on either…

机器学习 · 统计学 2025-01-13 Noga Mudrik , Yenho Chen , Eva Yezerets , Christopher J. Rozell , Adam S. Charles

Generative models of brain activity have been instrumental in testing hypothesized mechanisms underlying brain dynamics against experimental datasets. Beyond capturing the key mechanisms underlying spontaneous brain dynamics, these models…

神经元与认知 · 定量生物学 2024-11-18 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

Objective audio quality measurement systems often use perceptual models to predict the subjective quality scores of processed signals, as reported in listening tests. Most systems map different metrics of perceived degradation into a single…

音频与语音处理 · 电气工程与系统科学 2022-12-12 Pablo M. Delgado , Jürgen Herre

Localizing neuronal activity in the brain, both in time and in space, is a central challenge to advance the understanding of brain function. Because of the inability of any single neuroimaging techniques to cover all aspects at once, there…

神经元与认知 · 定量生物学 2013-07-09 Yaroslav O. Halchenko , Michael Hanke , James V. Haxby , Stephen Jose Hanson , Christoph S. Herrmann

Data-driven modeling techniques have been explored in the spatial-temporal modeling of complex dynamical systems for many engineering applications. However, a systematic approach is still lacking to leverage the information from different…

机器学习 · 计算机科学 2024-10-15 Chuanqi Chen , Jin-Long Wu

Knowledge about the collective dynamics of cortical spiking is very informative about the underlying coding principles. However, even most basic properties are not known with certainty, because their assessment is hampered by spatial…

神经元与认知 · 定量生物学 2019-03-13 Jens Wilting , Viola Priesemann

Large-scale neural mass models have been widely used to simulate resting-state brain activity from structural connectivity. In this work, we extend a well-established Wilson--Cowan framework by introducing a novel hemispheric-specific…

神经元与认知 · 定量生物学 2025-08-19 Ramiro Plüss , Hernán Villota , Patricio Orio

A new type of non-invasive deep-brain stimulation is conceived and demonstrated by computer simulations. The process is based on spatio-temporal Fourier synthesis using multiple electrode pairs with sinusoidal current drive to limit skin…

综合物理 · 物理学 2024-08-02 Laszlo B. Kish , Andrea Antal

A significant and rising proportion of the global population suffer from non-communicable diseases, such as neurological disorders. Neurorehabilitation aims to restore function and independence of neurological patients through providing…

Non-invasive assessment of the electrical activation pattern can significantly contribute to the diagnosis and treatment of cardiac arrhythmias, due to faster and safer diagnosis, improved surgical planning and easier follow-up. One…

医学物理 · 物理学 2024-01-09 Nathan Dermul , Hans Dierckx

Recent experimental advances in neuroscience have opened new vistas into the immense complexity of neuronal networks. This proliferation of data challenges us on two parallel fronts. First, how can we form adequate theoretical frameworks…

神经元与认知 · 定量生物学 2015-06-12 Madhu Advani , Subhaneil Lahiri , Surya Ganguli

Neural population activity often exhibits rich variability and temporal structure. This variability is thought to arise from single-neuron stochasticity, neural dynamics on short time-scales, as well as from modulations of neural firing…

机器学习 · 统计学 2014-10-14 Mijung Park , Jakob H. Macke

Simulation speed matters for neuroscientific research: this includes not only how quickly the simulated model time of a large-scale spiking neuronal network progresses, but also how long it takes to instantiate the network model in computer…

This paper studies linear mathematical modeling of brain's cortical dynamics using electroencephalography (EEG) data in an experiment with continuous exogenous input. The EEG data were recorded while participants were seated with their…

神经元与认知 · 定量生物学 2025-10-06 Sanna Bakels , Mark van de Ruit , Matin Jafarian

The brain is in a state of perpetual reverberant neural activity, even in the absence of specific tasks or stimuli. Shedding light on the origin and functional significance of such a dynamical state is essential to understanding how the…

统计力学 · 物理学 2022-07-08 Guillermo B. Morales , Serena Di Santo , Miguel A. Munoz

Various animals, including humans, have been suggested to perform Bayesian inferences to handle noisy, time-varying external information. In performing Bayesian inference, the prior distribution must be shaped by sampling noisy external…

神经元与认知 · 定量生物学 2022-10-25 Kohei Ichikawa , Kunihiko Kaneko

Much of our mechanistic understanding of the functions of biological macromolecules is based on static structural experiments, which can be modelled either as single structures or conformational ensembles. While these provide us with…

生物大分子 · 定量生物学 2025-10-02 Daria Gusew , Carl G. Henning Hansen , Kresten Lindorff-Larsen

To thrive in dynamic environments, animals must be capable of rapidly and flexibly adapting behavioral responses to a changing context and internal state. Examples of behavioral flexibility include faster stimulus responses when attentive…

神经元与认知 · 定量生物学 2021-01-27 David Wyrick , Luca Mazzucato

The models in statistical physics such as an Ising model offer a convenient way to characterize stationary activity of neural populations. Such stationary activity of neurons may be expected for recordings from in vitro slices or…

神经元与认知 · 定量生物学 2017-05-05 Christian Donner , Klaus Obermayer , Hideaki Shimazaki